ENSGALG00000004366


Gallus gallus

Features
Gene ID: ENSGALG00000004366
  
Biological name :BAP1
  
Synonyms : BAP1 / ubiquitin carboxyl-terminal hydrolase BAP1
  
Possible biological names infered from orthology : BRCA1 associated protein 1 / Q92560 / Q99PU7
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 3100374
Gene end: 3112954
  
Corresponding Affymetrix probe sets: Gga.5871.1.S1_a_at (Chicken Array)   Gga.5871.2.A1_at (Chicken Array)   GgaAffx.26189.1.S1_at (Chicken Array)   GgaAffx.26189.2.S1_at (Chicken Array)   GgaAffx.26189.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048912
Ensembl peptide - ENSGALP00000006954
NCBI entrez gene - 415944     See in Manteia.
RefSeq - NM_001030590
RefSeq Peptide - NP_001025761
swissprot - F1NVF5
swissprot - A0A1D5P867
Ensembl - ENSGALG00000004366
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bap1ENSDARG00000063051Danio rerio
 BAP1ENSG00000163930Homo sapiens
 Bap1ENSMUSG00000021901Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UCHL5 / ubiquitin carboxyl-terminal hydrolase isozyme L5 / Q9WUP7* / Q9Y5K5* / ubiquitin C-terminal hydrolase L5* / ubiquitin carboxyl-terminal esterase L5*ENSGALG0000000252417


Protein motifs (from Interpro)
Interpro ID Name
 IPR001578  Peptidase C12, ubiquitin carboxyl-terminal hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0010035 response to inorganic substance IEA
 biological_processGO:0016579 protein deubiquitination IEA
 biological_processGO:0035520 monoubiquitinated protein deubiquitination IEA
 biological_processGO:0035522 monoubiquitinated histone H2A deubiquitination IEA
 biological_processGO:0050727 regulation of inflammatory response IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0061519 macrophage homeostasis IEA
 biological_processGO:0071108 protein K48-linked deubiquitination IEA
 biological_processGO:1900015 regulation of cytokine production involved in inflammatory response IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0035517 PR-DUB complex IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA


Pathways (from Reactome)
Pathway description
UCH proteinases
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004460 FOXK1 / forkhead box K1 / P42128* / P85037* / Forkhead box protein K1 *  / reaction / complex
 ENSGALG00000006612 ASXL1 / additional sex combs like 1, transcriptional regulator / P59598* / Q8IXJ9* / Putative Polycomb group protein ASXL1 *  / reaction / complex
 ENSGALG00000005425 OGT / O-linked N-acetylglucosamine (GlcNAc) transferase / O15294* / Q8CGY8* / UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit *  / reaction / complex






 

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