ENSGALG00000005658


Gallus gallus

Features
Gene ID: ENSGALG00000005658
  
Biological name :FOXO4
  
Synonyms : forkhead box O4 / FOXO4
  
Possible biological names infered from orthology : Forkhead box protein O4 / P98177 / Q9WVH3
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 2424103
Gene end: 2432970
  
Corresponding Affymetrix probe sets: GgaAffx.3550.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000009065
NCBI entrez gene - 428703     See in Manteia.
RefSeq - XM_015278657
swissprot - F1NGG3
Ensembl - ENSGALG00000005658
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxo4ENSDARG00000055792Danio rerio
 FOXO4ENSG00000184481Homo sapiens
 Foxo4ENSMUSG00000042903Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOXO1 / forkhead box protein O1 / Q12778* / Q9R1E0* / forkhead box O1*ENSGALG0000001703446
FOXO3 / forkhead box O3 / O43524* / Q9WVH4* / Forkhead box protein O3 *ENSGALG0000001529744
FOXO6 / forkhead box O6 / A8MYZ6* / Q70KY4* / Forkhead box protein O6 *ENSGALG0000002615330
FOXM1 / forkhead box protein M1 / Q08050* / forkhead box M1*ENSGALG0000001342013
FOXM1* / Q08050* / forkhead box M1*ENSGALG000000407345


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR030456  Fork head domain conserved site 2
 IPR032067  FOXO protein, transactivation domain
 IPR032068  FOXO protein, KIX-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0007095 mitotic G2 DNA damage checkpoint IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008286 insulin receptor signaling pathway IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048863 stem cell differentiation IEA
 biological_processGO:0051151 negative regulation of smooth muscle cell differentiation IEA
 biological_processGO:0070317 negative regulation of G0 to G1 transition IEA
 biological_processGO:0071158 positive regulation of cell cycle arrest IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
AKT phosphorylates targets in the nucleus
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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