ENSGALG00000005857


Gallus gallus

Features
Gene ID: ENSGALG00000005857
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : ALOX5 / arachidonate 5-lipoxygenase / P09917 / P48999
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 17636489
Gene end: 17657686
  
Corresponding Affymetrix probe sets: Gga.9109.1.S1_at (Chicken Array)   GgaAffx.3623.1.S1_at (Chicken Array)   GgaAffx.3662.1.S1_at (Chicken Array)   GgaAffx.3664.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050475
Ensembl peptide - ENSGALP00000009402
NCBI entrez gene - 423769     See in Manteia.
RefSeq - XM_015288448
RefSeq - XM_003641512
swissprot - F1NB65
swissprot - A0A1D5PCI6
Ensembl - ENSGALG00000005857
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 alox5aENSDARG00000057273Danio rerio
 alox5b.1ENSDARG00000043085Danio rerio
 alox5b.2ENSDARG00000043089Danio rerio
 alox5b.3ENSDARG00000069966Danio rerio
 ALOX5ENSG00000012779Homo sapiens
 Alox5ENSMUSG00000025701Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000907  Lipoxygenase
 IPR001024  PLAT/LH2 domain
 IPR001885  Lipoxygenase, mammalian
 IPR013819  Lipoxygenase, C-terminal
 IPR020833  Lipoxygenase, iron binding site
 IPR020834  Lipoxygenase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of 5-eicosatetraenoic acids
Synthesis of Leukotrienes (LT) and Eoxins (EX)
Synthesis of Lipoxins (LX)
Neutrophil degranulation
Biosynthesis of D-series resolvins
Biosynthesis of maresins
Biosynthesis of E-series 18(S)-resolvins
Biosynthesis of aspirin-triggered D-series resolvins
Biosynthesis of E-series 18(R)-resolvins
Biosynthesis of DPAn-3-derived protectins and resolvins
Biosynthesis of DPAn-3-derived maresins
Biosynthesis of DPAn-3-derived 13-series resolvins
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000883 MAPKAPK2 / mitogen-activated protein kinase-activated protein kinase 2 / P49137* / P49138* / MAP kinase-activated protein kinase 2 *  / reaction
 ENSGALG00000026781 ALOX5AP / arachidonate 5-lipoxygenase activating protein / P20292* / P30355*  / complex






 

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