ENSGALG00000005902


Gallus gallus

Features
Gene ID: ENSGALG00000005902
  
Biological name :RAB7A
  
Synonyms : RAB7A / RAB7A, member RAS oncogene family
  
Possible biological names infered from orthology : P51149 / P51150 / Rab7 / RAB7, member RAS oncogene family
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 9136507
Gene end: 9163214
  
Corresponding Affymetrix probe sets: Gga.11788.1.S1_at (Chicken Array)   Gga.19067.1.S1_at (Chicken Array)   Gga.5872.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000009481
Ensembl peptide - ENSGALP00000063992
Ensembl peptide - ENSGALP00000060629
Ensembl peptide - ENSGALP00000043856
NCBI entrez gene - 416016     See in Manteia.
RefSeq - XM_003641978
swissprot - E1C0F3
swissprot - A0A1L1RYR3
swissprot - A0A1D5NU47
Ensembl - ENSGALG00000005902
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab7ENSDARG00000020497Danio rerio
 RAB7AENSG00000075785Homo sapiens
 Rab7ENSMUSG00000079477Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAB9B / RAB9B, member RAS oncogene family / Q8BHH2* / Q9NP90*ENSGALG0000000491852
RAB7B / RAB7B, member RAS oncogene family / Q8VEA8* / Q96AH8*ENSGALG0000000076952
RAB9A / RAB9A, member RAS oncogene family / Rab9* / Q9R0M6* / P51151* / RAB9, member RAS oncogene family*ENSGALG0000001657949
RAB32 / RAB32, member RAS oncogene family / Q13637* / Q9CZE3*ENSGALG0000001230034
RAB23 / ras-related protein Rab-23 / Q9ULC3* / RAB23, member RAS oncogene family*ENSGALG0000001627933
RAB38 / RAB38, member RAS oncogene family / P57729* / Q8QZZ8*ENSGALG0000002801832
RAB29 / RAB29, member RAS oncogene family / O14966*ENSGALG0000000071230


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IEA
 biological_processGO:0006622 protein targeting to lysosome IEA
 biological_processGO:0007174 epidermal growth factor catabolic process IEA
 biological_processGO:0008333 endosome to lysosome transport IEA
 biological_processGO:0019076 viral release from host cell IEA
 biological_processGO:0022615 protein to membrane docking IEA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IEA
 biological_processGO:0045022 early endosome to late endosome transport IEA
 biological_processGO:0045732 positive regulation of protein catabolic process IEA
 biological_processGO:0048524 positive regulation of viral process IEA
 biological_processGO:0061724 lipophagy IEA
 biological_processGO:0090383 phagosome acidification IEA
 biological_processGO:0090385 phagosome-lysosome fusion IEA
 biological_processGO:1903542 negative regulation of exosomal secretion IEA
 biological_processGO:1903543 positive regulation of exosomal secretion IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005811 lipid droplet IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0030904 retromer complex IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0032419 extrinsic component of lysosome membrane IEA
 cellular_componentGO:0034045 phagophore assembly site membrane IEA
 cellular_componentGO:0045335 phagocytic vesicle IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019003 GDP binding IEA
 molecular_functionGO:1905394 retromer complex binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
TBC/RABGAPs
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002919 MON1A / vacuolar fusion protein MON1 homolog A / Q86VX9* / MON1 homolog A, secretory trafficking associated*  / reaction






 

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