ENSGALG00000006035


Gallus gallus

Features
Gene ID: ENSGALG00000006035
  
Biological name :PDE3B
  
Synonyms : cGMP-inhibited 3,5-cyclic phosphodiesterase B / PDE3B
  
Possible biological names infered from orthology : phosphodiesterase 3B / Q13370
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 10434605
Gene end: 10509846
  
Corresponding Affymetrix probe sets: Gga.3624.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000038821
NCBI entrez gene - 423064     See in Manteia.
RefSeq - NM_001031182
RefSeq Peptide - NP_001026353
swissprot - F1NFJ5
Ensembl - ENSGALG00000006035
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PDE3BENSDARG00000062190Danio rerio
 PDE3BENSG00000152270Homo sapiens
 Pde3bENSMUSG00000030671Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDE3A / phosphodiesterase 3A / Q14432* / Q9Z0X4* / phosphodiesterase 3A, cGMP inhibited*ENSGALG0000001314337
PDE6B / Gallus gallus phosphodiesterase 6B (PDE6B), mRNA. / P35913* / P23440* / phosphodiesterase 6B* / phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide*ENSGALG0000001537313
P0C1Q2* / PDE11A* / Q9HCR9* / phosphodiesterase 11A* / Dual 3,5-cyclic-AMP and -GMP phosphodiesterase 11A *ENSGALG0000004237412
PDE6C / cone cGMP-specific 3,5-cyclic phosphodiesterase subunit alpha / P51160* / Q91ZQ1* / phosphodiesterase 6C*ENSGALG0000000662612
PDE5A / Gallus gallus phosphodiesterase 5A (PDE5A), mRNA. / O76074* / Q8CG03* / phosphodiesterase 5A* / cGMP-specific 3,5-cyclic phosphodiesterase *ENSGALG0000001198211
PDE10A / phosphodiesterase 10A / Q8CA95* / Q9Y233*ENSGALG0000001153710
PDE9A / phosphodiesterase 9A / O70628* / O76083* / High affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A *ENSGALG000000161869


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003607  HD/PDEase domain
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006198 cAMP catabolic process IEA
 biological_processGO:0007162 negative regulation of cell adhesion IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0050995 negative regulation of lipid catabolic process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032045 guanyl-nucleotide exchange factor complex IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
PDE3B signalling
cGMP effects
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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