ENSGALG00000011982


Gallus gallus

Features
Gene ID: ENSGALG00000011982
  
Biological name :PDE5A
  
Synonyms : Gallus gallus phosphodiesterase 5A (PDE5A), mRNA. / PDE5A
  
Possible biological names infered from orthology : cGMP-specific 3,5-cyclic phosphodiesterase / O76074 / phosphodiesterase 5A / Q8CG03
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 55000129
Gene end: 55059970
  
Corresponding Affymetrix probe sets: Gga.14226.1.S1_s_at (Chicken Array)   GgaAffx.23721.1.S1_at (Chicken Array)   GgaAffx.23721.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019524
Ensembl peptide - ENSGALP00000057558
NCBI entrez gene - 422677     See in Manteia.
RefSeq - XM_420631
RefSeq - NM_001319020
RefSeq - XM_004941239
RefSeq - XM_015276368
RefSeq - XM_015276369
RefSeq - XM_004941236
RefSeq - XM_004941237
RefSeq - XM_004941238
RefSeq Peptide - NP_001305949
swissprot - S4SCC1
swissprot - F1NHB7
Ensembl - ENSGALG00000011982
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pde5abENSDARG00000051915Danio rerio
 PDE5AENSG00000138735Homo sapiens
 Pde5aENSMUSG00000053965Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P0C1Q2* / PDE11A* / Q9HCR9* / phosphodiesterase 11A* / Dual 3,5-cyclic-AMP and -GMP phosphodiesterase 11A *ENSGALG0000004237438
PDE6B / Gallus gallus phosphodiesterase 6B (PDE6B), mRNA. / P35913* / P23440* / phosphodiesterase 6B* / phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide*ENSGALG0000001537330
PDE6C / cone cGMP-specific 3,5-cyclic phosphodiesterase subunit alpha / P51160* / Q91ZQ1* / phosphodiesterase 6C*ENSGALG0000000662629
PDE10A / phosphodiesterase 10A / Q8CA95* / Q9Y233*ENSGALG0000001153726
PDE3B / cGMP-inhibited 3,5-cyclic phosphodiesterase B / Q13370* / phosphodiesterase 3B*ENSGALG0000000603513
PDE3A / phosphodiesterase 3A / Q14432* / Q9Z0X4* / phosphodiesterase 3A, cGMP inhibited*ENSGALG0000001314312
PDE9A / phosphodiesterase 9A / O70628* / O76083* / High affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A *ENSGALG0000001618610


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003018  GAF domain
 IPR003607  HD/PDEase domain
 IPR023088  3"5"-cyclic nucleotide phosphodiesterase
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site
 IPR029016  GAF-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy IEA
 biological_processGO:0030823 obsolete regulation of cGMP metabolic process IEA
 biological_processGO:0042130 negative regulation of T cell proliferation IEA
 biological_processGO:0043406 positive regulation of MAP kinase activity IEA
 biological_processGO:0046068 cGMP metabolic process IEA
 biological_processGO:0046069 cGMP catabolic process IEA
 biological_processGO:0055118 negative regulation of cardiac muscle contraction IEA
 biological_processGO:0055119 relaxation of cardiac muscle IEA
 biological_processGO:0060282 positive regulation of oocyte development IEA
 molecular_functionGO:0004112 cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030553 cGMP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
cGMP effects


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr