ENSGALG00000011537


Gallus gallus

Features
Gene ID: ENSGALG00000011537
  
Biological name :PDE10A
  
Synonyms : PDE10A / phosphodiesterase 10A
  
Possible biological names infered from orthology : Q8CA95 / Q9Y233
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 43375111
Gene end: 43466306
  
Corresponding Affymetrix probe sets: GgaAffx.7289.1.S1_at (Chicken Array)   GgaAffx.7310.1.S1_at (Chicken Array)   GgaAffx.7314.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018787
NCBI entrez gene - 421574     See in Manteia.
RefSeq - XM_004935552
RefSeq - XM_004935553
RefSeq - XM_004935554
RefSeq - XM_015284334
RefSeq - XM_015284335
RefSeq - XM_004935551
swissprot - F1NZ06
Ensembl - ENSGALG00000011537
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pde10aENSDARG00000003449Danio rerio
 PDE10AENSG00000112541Homo sapiens
 Pde10aENSMUSG00000023868Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDE5A / Gallus gallus phosphodiesterase 5A (PDE5A), mRNA. / O76074* / Q8CG03* / phosphodiesterase 5A* / cGMP-specific 3,5-cyclic phosphodiesterase *ENSGALG0000001198229
P0C1Q2* / PDE11A* / Q9HCR9* / phosphodiesterase 11A* / Dual 3,5-cyclic-AMP and -GMP phosphodiesterase 11A *ENSGALG0000004237428
PDE6B / Gallus gallus phosphodiesterase 6B (PDE6B), mRNA. / P35913* / P23440* / phosphodiesterase 6B* / phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide*ENSGALG0000001537326
PDE6C / cone cGMP-specific 3,5-cyclic phosphodiesterase subunit alpha / P51160* / Q91ZQ1* / phosphodiesterase 6C*ENSGALG0000000662624
PDE3B / cGMP-inhibited 3,5-cyclic phosphodiesterase B / Q13370* / phosphodiesterase 3B*ENSGALG0000000603514
PDE3A / phosphodiesterase 3A / Q14432* / Q9Z0X4* / phosphodiesterase 3A, cGMP inhibited*ENSGALG0000001314313
PDE9A / phosphodiesterase 9A / O70628* / O76083* / High affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A *ENSGALG0000001618611


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003018  GAF domain
 IPR003607  HD/PDEase domain
 IPR023088  3"5"-cyclic nucleotide phosphodiesterase
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site
 IPR029016  GAF-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0010738 regulation of protein kinase A signaling IEA
 biological_processGO:0043949 regulation of cAMP-mediated signaling IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030552 cAMP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
cGMP effects
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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