ENSGALG00000007354


Gallus gallus

Features
Gene ID: ENSGALG00000007354
  
Biological name :CIT
  
Synonyms : CIT / citron rho-interacting serine/threonine kinase
  
Possible biological names infered from orthology : O14578
  
Species: Gallus gallus
  
Chr. number: 15
Strand: 1
Band:
Gene start: 9611096
Gene end: 9680292
  
Corresponding Affymetrix probe sets: Gga.14334.1.S1_at (Chicken Array)   Gga.5074.1.S1_at (Chicken Array)   GgaAffx.22221.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000011881
NCBI entrez gene - 416984     See in Manteia.
RefSeq - XM_004934402
RefSeq - XM_004934403
RefSeq - XM_004934404
RefSeq - XM_004934405
RefSeq - XM_004934406
RefSeq - XM_015275389
RefSeq - XM_015275391
RefSeq - XM_015275392
RefSeq - XM_015275393
RefSeq - XM_015275394
RefSeq - XM_004934401
swissprot - E1C849
Ensembl - ENSGALG00000007354
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 citbENSDARG00000088825Danio rerio
 CITENSG00000122966Homo sapiens
 CitENSMUSG00000029516Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDC42BPA / CDC42 binding protein kinase alpha / Q3UU96* / Q5VT25* / Serine/threonine-protein kinase MRCK alpha *ENSGALG0000000915823
CDC42BPB / CDC42 binding protein kinase beta / Q7TT50* / Q9Y5S2*ENSGALG0000001143221
ROCK2 / Rho associated coiled-coil containing protein kinase 2 / O75116*ENSGALG0000001645117
ROCK1 / Rho associated coiled-coil containing protein kinase 1 / P70335* / Q13464* / Rho-associated protein kinase 1 *ENSGALG0000001492216
LATS1 / large tumor suppressor kinase 1 / O95835* / Q8BYR2* / Serine/threonine-protein kinase LATS1 *ENSGALG000000123868
STK38L / serine/threonine kinase 38 like / Q7TSE6* / Q9Y2H1* / Mus musculus serine/threonine kinase 38 like (Stk38l), transcript variant 2, mRNA.*ENSGALG000000140947
STK38 / serine/threonine kinase 38 / Q15208* / Q91VJ4* / Mus musculus serine/threonine kinase 38 (Stk38), transcript variant 2, mRNA.*ENSGALG000000005237


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR001180  Citron homology (CNH) domain
 IPR001849  Pleckstrin homology domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011993  PH-like domain superfamily
 IPR017405  Citron Rho-interacting kinase
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000281 mitotic cytokinesis IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0032467 positive regulation of cytokinesis IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0051402 neuron apoptotic process IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0097110 scaffold protein binding IEA


Pathways (from Reactome)
Pathway description
RHO GTPases activate CIT


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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