ENSGALG00000009158


Gallus gallus

Features
Gene ID: ENSGALG00000009158
  
Biological name :CDC42BPA
  
Synonyms : CDC42 binding protein kinase alpha / CDC42BPA
  
Possible biological names infered from orthology : Q3UU96 / Q5VT25 / Serine/threonine-protein kinase MRCK alpha
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 12273168
Gene end: 12439182
  
Corresponding Affymetrix probe sets: Gga.1621.2.S1_s_at (Chicken Array)   GgaAffx.22822.1.S1_s_at (Chicken Array)   GgaAffx.22822.3.S1_at (Chicken Array)   GgaAffx.5788.1.S1_at (Chicken Array)   GgaAffx.5788.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000038574
Ensembl peptide - ENSGALP00000014905
NCBI entrez gene - 416746     See in Manteia.
RefSeq - XM_015283520
RefSeq - XM_015283516
RefSeq - XM_015283517
RefSeq - XM_015283518
RefSeq - NM_001199443
RefSeq - XM_015283508
RefSeq - XM_015283509
RefSeq - XM_015283510
RefSeq - XM_015283511
RefSeq - XM_015283512
RefSeq - XM_015283513
RefSeq - XM_015283514
RefSeq - XM_015283515
RefSeq Peptide - NP_001186372
swissprot - F1NUB2
swissprot - E1BWT5
Ensembl - ENSGALG00000009158
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc42bpaaENSDARG00000104283Danio rerio
 cdc42bpabENSDARG00000016464Danio rerio
 Q5VT25ENSG00000143776Homo sapiens
 Q3UU96ENSMUSG00000026490Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDC42BPB / CDC42 binding protein kinase beta / Q7TT50* / Q9Y5S2*ENSGALG0000001143261
CIT / citron rho-interacting serine/threonine kinase / O14578*ENSGALG0000000735426
ROCK1 / Rho associated coiled-coil containing protein kinase 1 / P70335* / Q13464* / Rho-associated protein kinase 1 *ENSGALG0000001492221
ROCK2 / Rho associated coiled-coil containing protein kinase 2 / O75116*ENSGALG0000001645120
STK38L / serine/threonine kinase 38 like / Q7TSE6* / Q9Y2H1* / Mus musculus serine/threonine kinase 38 like (Stk38l), transcript variant 2, mRNA.*ENSGALG0000001409410
STK38 / serine/threonine kinase 38 / Q15208* / Q91VJ4* / Mus musculus serine/threonine kinase 38 (Stk38), transcript variant 2, mRNA.*ENSGALG0000000052310
LATS1 / large tumor suppressor kinase 1 / O95835* / Q8BYR2* / Serine/threonine-protein kinase LATS1 *ENSGALG000000123869


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR001180  Citron homology (CNH) domain
 IPR001849  Pleckstrin homology domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011993  PH-like domain superfamily
 IPR014930  Myotonic dystrophy protein kinase, coiled coil
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal
 IPR017986  WD40-repeat-containing domain
 IPR026611  Serine/threonine-protein kinase MRCK alpha
 IPR031597  KELK-motif containing domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0031032 actomyosin structure organization IEA
 biological_processGO:0031532 actin cytoskeleton reorganization IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0042641 actomyosin IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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