ENSMUSG00000026490


Mus musculus

Features
Gene ID: ENSMUSG00000026490
  
Biological name :Cdc42bpa
  
Synonyms : Cdc42bpa / Q3UU96 / Serine/threonine-protein kinase MRCK alpha
  
Possible biological names infered from orthology : CDC42 binding protein kinase alpha / Q5VT25
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H4
Gene start: 179960472
Gene end: 180165603
  
Corresponding Affymetrix probe sets: 10352194 (MoGene1.0st)   1435847_at (Mouse Genome 430 2.0 Array)   1436380_at (Mouse Genome 430 2.0 Array)   1438449_at (Mouse Genome 430 2.0 Array)   1442260_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116337
Ensembl peptide - ENSMUSP00000115261
Ensembl peptide - ENSMUSP00000118039
Ensembl peptide - ENSMUSP00000148469
Ensembl peptide - ENSMUSP00000142018
Ensembl peptide - ENSMUSP00000075980
Ensembl peptide - ENSMUSP00000095059
Ensembl peptide - ENSMUSP00000095062
Ensembl peptide - ENSMUSP00000106746
Ensembl peptide - ENSMUSP00000114333
NCBI entrez gene - 226751     See in Manteia.
MGI - MGI:2441841
RefSeq - XM_017320148
RefSeq - XM_011238802
RefSeq - XM_011238803
RefSeq - XM_011238804
RefSeq - XM_017320119
RefSeq - XM_017320127
RefSeq - XM_017320129
RefSeq - XM_017320130
RefSeq - XM_017320131
RefSeq - XM_017320132
RefSeq - XM_017320134
RefSeq - XM_017320142
RefSeq - XM_017320145
RefSeq - XM_017320146
RefSeq - NM_001033285
RefSeq - XM_006496801
RefSeq - XM_006496802
RefSeq - XM_006496803
RefSeq - XM_006496804
RefSeq - XM_006496805
RefSeq - XM_006496806
RefSeq - XM_006496807
RefSeq - XM_006496808
RefSeq - XM_006496809
RefSeq - XM_006496810
RefSeq - XM_006496812
RefSeq - XM_006496813
RefSeq Peptide - NP_001333733
RefSeq Peptide - NP_001333734
RefSeq Peptide - NP_001028457
swissprot - F6S5Z6
swissprot - F6W0C2
swissprot - F6YZJ7
swissprot - H7BX44
swissprot - A0A1D5RLQ9
swissprot - A0A0A6YXJ5
swissprot - E9PVY0
swissprot - Q3UU96
swissprot - D3YYN8
swissprot - F6Q5A5
Ensembl - ENSMUSG00000026490
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc42bpaaENSDARG00000104283Danio rerio
 cdc42bpabENSDARG00000016464Danio rerio
 CDC42BPAENSGALG00000009158Gallus gallus
 Q5VT25ENSG00000143776Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q7TT50 / Cdc42bpb / CDC42 binding protein kinase beta / Q9Y5S2*ENSMUSG0000002127961
Q80UW5 / Cdc42bpg / Serine/threonine-protein kinase MRCK gamma / Q6DT37* / CDC42 binding protein kinase gamma*ENSMUSG0000002476942
Cit / citron rho-interacting serine/threonine kinase / O14578*ENSMUSG0000002951626
Rock1 / P70335 / Rho-associated protein kinase 1 / Q13464* / Rho associated coiled-coil containing protein kinase 1*ENSMUSG0000002429021
Rock2 / Rho associated coiled-coil containing protein kinase 2 / O75116*ENSMUSG0000002058021
Dmpk / P54265 / Myotonin-protein kinase / Q09013* / DM1 protein kinase*ENSMUSG0000003040917
Lats2 / Q7TSJ6 / Serine/threonine-protein kinase LATS2 / Q9NRM7* / large tumor suppressor kinase 2*ENSMUSG0000002195910
Stk38 / Q91VJ4 / Mus musculus serine/threonine kinase 38 (Stk38), transcript variant 2, mRNA. / Q15208* / serine/threonine kinase 38*ENSMUSG0000002400610
Q7TSE6 / Stk38l / Mus musculus serine/threonine kinase 38 like (Stk38l), transcript variant 2, mRNA. / Q9Y2H1* / serine/threonine kinase 38 like*ENSMUSG0000000163010
Lats1 / Q8BYR2 / Serine/threonine-protein kinase LATS1 / O95835* / large tumor suppressor kinase 1*ENSMUSG000000400219
Lats2 / Q9NRM7* / large tumor suppressor kinase 2*ENSMUSG000001149426


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR001180  Citron homology (CNH) domain
 IPR001849  Pleckstrin homology domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011993  PH-like domain superfamily
 IPR014930  Myotonic dystrophy protein kinase, coiled coil
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal
 IPR020454  Diacylglycerol/phorbol-ester binding
 IPR026611  Serine/threonine-protein kinase MRCK alpha
 IPR031597  KELK-motif containing domain
 IPR036936  CRIB domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IMP
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007097 nuclear migration IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration ISO
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0031032 actomyosin structure organization ISO
 biological_processGO:0031532 actin cytoskeleton reorganization ISO
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0042641 actomyosin ISO
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding ISO
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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