ENSMUSG00000024769


Mus musculus

Features
Gene ID: ENSMUSG00000024769
  
Biological name :Cdc42bpg
  
Synonyms : Cdc42bpg / Q80UW5 / Serine/threonine-protein kinase MRCK gamma
  
Possible biological names infered from orthology : CDC42 binding protein kinase gamma / Q6DT37
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: A
Gene start: 6306456
Gene end: 6325652
  
Corresponding Affymetrix probe sets: 10460841 (MoGene1.0st)   1436197_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025681
NCBI entrez gene - 240505     See in Manteia.
MGI - MGI:2652845
RefSeq - XM_017318192
RefSeq - NM_001033342
RefSeq - XM_006531744
RefSeq - XM_017318191
RefSeq - XM_006531743
RefSeq Peptide - NP_001028514
swissprot - Q80UW5
Ensembl - ENSMUSG00000024769
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6DT37ENSG00000171219Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3UU96 / Cdc42bpa / Serine/threonine-protein kinase MRCK alpha / Q5VT25* / CDC42 binding protein kinase alpha*ENSMUSG0000002649047
Q7TT50 / Cdc42bpb / CDC42 binding protein kinase beta / Q9Y5S2*ENSMUSG0000002127946
Cit / citron rho-interacting serine/threonine kinase / O14578*ENSMUSG0000002951626
Rock1 / P70335 / Rho-associated protein kinase 1 / Q13464* / Rho associated coiled-coil containing protein kinase 1*ENSMUSG0000002429022
Rock2 / Rho associated coiled-coil containing protein kinase 2 / O75116*ENSMUSG0000002058021
Dmpk / P54265 / Myotonin-protein kinase / Q09013* / DM1 protein kinase*ENSMUSG0000003040920
Lats2 / Q7TSJ6 / Serine/threonine-protein kinase LATS2 / Q9NRM7* / large tumor suppressor kinase 2*ENSMUSG0000002195911
Q7TSE6 / Stk38l / Mus musculus serine/threonine kinase 38 like (Stk38l), transcript variant 2, mRNA. / Q9Y2H1* / serine/threonine kinase 38 like*ENSMUSG0000000163011
Lats1 / Q8BYR2 / Serine/threonine-protein kinase LATS1 / O95835* / large tumor suppressor kinase 1*ENSMUSG0000004002110
Stk38 / Q91VJ4 / Mus musculus serine/threonine kinase 38 (Stk38), transcript variant 2, mRNA. / Q15208* / serine/threonine kinase 38*ENSMUSG0000002400610
Lats2 / Q9NRM7* / large tumor suppressor kinase 2*ENSMUSG000001149426


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR001180  Citron homology (CNH) domain
 IPR001849  Pleckstrin homology domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011993  PH-like domain superfamily
 IPR014930  Myotonic dystrophy protein kinase, coiled coil
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal
 IPR033235  Serine/threonine-protein kinase MRCK gamma


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation ISS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0031532 actin cytoskeleton reorganization ISS
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0031252 cell leading edge IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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