ENSMUSG00000021279


Mus musculus

Features
Gene ID: ENSMUSG00000021279
  
Biological name :Cdc42bpb
  
Synonyms : CDC42 binding protein kinase beta / Cdc42bpb / Q7TT50
  
Possible biological names infered from orthology : Q9Y5S2
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: F1
Gene start: 111292976
Gene end: 111377718
  
Corresponding Affymetrix probe sets: 10402665 (MoGene1.0st)   1434652_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000042565
Ensembl peptide - ENSMUSP00000152832
Ensembl peptide - ENSMUSP00000152591
Ensembl peptide - ENSMUSP00000152475
NCBI entrez gene - 217866     See in Manteia.
MGI - MGI:2136459
RefSeq - XM_006515763
RefSeq - NM_183016
RefSeq Peptide - NP_898837
swissprot - A0A1Y7VLI0
swissprot - A0A1Y7VM95
swissprot - Q7TT50
swissprot - A0A1Y7VKD5
Ensembl - ENSMUSG00000021279
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc42bpaaENSDARG00000104283Danio rerio
 cdc42bpabENSDARG00000016464Danio rerio
 CDC42BPBENSGALG00000011432Gallus gallus
 Q9Y5S2ENSG00000198752Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3UU96 / Cdc42bpa / Serine/threonine-protein kinase MRCK alpha / Q5VT25* / CDC42 binding protein kinase alpha*ENSMUSG0000002649062
Q80UW5 / Cdc42bpg / Serine/threonine-protein kinase MRCK gamma / Q6DT37* / CDC42 binding protein kinase gamma*ENSMUSG0000002476941
Cit / citron rho-interacting serine/threonine kinase / O14578*ENSMUSG0000002951627
Rock1 / P70335 / Rho-associated protein kinase 1 / Q13464* / Rho associated coiled-coil containing protein kinase 1*ENSMUSG0000002429022
Rock2 / Rho associated coiled-coil containing protein kinase 2 / O75116*ENSMUSG0000002058021
Dmpk / P54265 / Myotonin-protein kinase / Q09013* / DM1 protein kinase*ENSMUSG0000003040918
Stk38 / Q91VJ4 / Mus musculus serine/threonine kinase 38 (Stk38), transcript variant 2, mRNA. / Q15208* / serine/threonine kinase 38*ENSMUSG0000002400610
Lats2 / Q7TSJ6 / Serine/threonine-protein kinase LATS2 / Q9NRM7* / large tumor suppressor kinase 2*ENSMUSG0000002195910
Q7TSE6 / Stk38l / Mus musculus serine/threonine kinase 38 like (Stk38l), transcript variant 2, mRNA. / Q9Y2H1* / serine/threonine kinase 38 like*ENSMUSG0000000163010
Lats1 / Q8BYR2 / Serine/threonine-protein kinase LATS1 / O95835* / large tumor suppressor kinase 1*ENSMUSG000000400219
Lats2 / Q9NRM7* / large tumor suppressor kinase 2*ENSMUSG000001149426


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR001180  Citron homology (CNH) domain
 IPR001849  Pleckstrin homology domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011993  PH-like domain superfamily
 IPR014930  Myotonic dystrophy protein kinase, coiled coil
 IPR017441  Protein kinase, ATP binding site
 IPR020454  Diacylglycerol/phorbol-ester binding
 IPR031597  KELK-motif containing domain
 IPR033232  Serine/threonine-protein kinase MRCK beta
 IPR036936  CRIB domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0031032 actomyosin structure organization IEA
 biological_processGO:0031532 actin cytoskeleton reorganization ISS
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030027 lamellipodium ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031252 cell leading edge ISS
 cellular_componentGO:0042641 actomyosin IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding ISS
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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