ENSMUSG00000001630


Mus musculus

Features
Gene ID: ENSMUSG00000001630
  
Biological name :Stk38l
  
Synonyms : Mus musculus serine/threonine kinase 38 like (Stk38l), transcript variant 2, mRNA. / Q7TSE6 / Stk38l
  
Possible biological names infered from orthology : Q9Y2H1 / serine/threonine kinase 38 like
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: G3
Gene start: 146724995
Gene end: 146778812
  
Corresponding Affymetrix probe sets: 10542757 (MoGene1.0st)   1435877_at (Mouse Genome 430 2.0 Array)   1435878_at (Mouse Genome 430 2.0 Array)   1455183_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000001675
Ensembl peptide - ENSMUSP00000107271
Ensembl peptide - ENSMUSP00000145209
NCBI entrez gene - 232533     See in Manteia.
MGI - MGI:1922250
RefSeq - XM_017321560
RefSeq - NM_001346666
RefSeq - NM_172734
RefSeq - XM_006507031
RefSeq - XM_006507032
RefSeq - XM_006507033
RefSeq - XM_006507034
RefSeq - XM_006507027
RefSeq - XM_006507029
RefSeq Peptide - NP_001333595
RefSeq Peptide - NP_766322
swissprot - Q7TSE6
swissprot - A0A0N4SVR1
Ensembl - ENSMUSG00000001630
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stk38lENSDARG00000045482Danio rerio
 STK38LENSGALG00000014094Gallus gallus
 Q9Y2H1ENSG00000211455Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Stk38 / Q91VJ4 / Mus musculus serine/threonine kinase 38 (Stk38), transcript variant 2, mRNA. / Q15208* / serine/threonine kinase 38*ENSMUSG0000002400686
Lats1 / Q8BYR2 / Serine/threonine-protein kinase LATS1 / O95835* / large tumor suppressor kinase 1*ENSMUSG0000004002142
Lats2 / Q7TSJ6 / Serine/threonine-protein kinase LATS2 / Q9NRM7* / large tumor suppressor kinase 2*ENSMUSG0000002195942
Q3UU96 / Cdc42bpa / Serine/threonine-protein kinase MRCK alpha / Q5VT25* / CDC42 binding protein kinase alpha*ENSMUSG0000002649037
Q7TT50 / Cdc42bpb / CDC42 binding protein kinase beta / Q9Y5S2*ENSMUSG0000002127936
Q80UW5 / Cdc42bpg / Serine/threonine-protein kinase MRCK gamma / Q6DT37* / CDC42 binding protein kinase gamma*ENSMUSG0000002476936
Rock1 / P70335 / Rho-associated protein kinase 1 / Q13464* / Rho associated coiled-coil containing protein kinase 1*ENSMUSG0000002429034
Rock2 / Rho associated coiled-coil containing protein kinase 2 / O75116*ENSMUSG0000002058033
Dmpk / P54265 / Myotonin-protein kinase / Q09013* / DM1 protein kinase*ENSMUSG0000003040932
Cit / citron rho-interacting serine/threonine kinase / O14578*ENSMUSG0000002951629
Lats2 / Q9NRM7* / large tumor suppressor kinase 2*ENSMUSG0000011494228


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation ISS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction ISS
 biological_processGO:0051128 regulation of cellular component organization IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding ISO
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008572 abnormal Purkinje cell dendrite morphology "any strucutral anomaly of the Purkinje cell body projections with hundreds of parallel spiny branches reaching up into the molecular layer" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tyrm5Btlr/Tyrm5Btlr
Genetic Background: C57BL/6J-Tyrm5Btlr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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