ENSGALG00000007732


Gallus gallus

Features
Gene ID: ENSGALG00000007732
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : Q99PI8 / Q9BZR6 / reticulon 4 receptor / RTN4R
  
Species: Gallus gallus
  
Chr. number: 15
Strand: 1
Band:
Gene start: 10383102
Gene end: 10447744
  
Corresponding Affymetrix probe sets: Gga.2536.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012522
NCBI entrez gene - 417001     See in Manteia.
RefSeq - XM_415292
swissprot - F1NRZ3
Ensembl - ENSGALG00000007732
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rtn4rENSDARG00000090035Danio rerio
 RTN4RENSG00000040608Homo sapiens
 Rtn4rENSMUSG00000043811Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RTN4RL1 / reticulon 4 receptor like 1 / Q86UN2* / Q8K0S5*ENSGALG0000002158937
RTN4RL2 / reticulon 4 receptor like 2 / Q7M6Z0* / Q86UN3*ENSGALG0000003290333
LRTM1 / leucine rich repeats and transmembrane domains 1 / Q8BXQ3* / Q9HBL6* / Leucine-rich repeat and transmembrane domain-containing protein 1 *ENSGALG0000000540414
LRTM2 / leucine rich repeats and transmembrane domains 2 / Q8BGX3* / Q8N967* / Leucine-rich repeat and transmembrane domain-containing protein 2 *ENSGALG0000002621414
LRRC38 / leucine rich repeat containing 38 / A2VDH3* / Q5VT99* / Leucine-rich repeat-containing protein 38 *ENSGALG0000000409714
LRRC26* / Q2I0M4* / Q91W20* / leucine rich repeat containing 26* / Leucine-rich repeat-containing protein 26 *ENSGALG0000004590113
LRRC52 / leucine rich repeat containing 52 / Q5M8M9* / Q8N7C0* / Leucine-rich repeat-containing protein 52 *ENSGALG0000000344312
LRRC55 / leucine rich repeat containing 55 / Q3UY51* / Q6ZSA7* / Leucine-rich repeat-containing protein 55 *ENSGALG0000002913012


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0010977 negative regulation of neuron projection development IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0022038 corpus callosum development IEA
 biological_processGO:0023041 neuronal signal transduction IEA
 biological_processGO:0030517 negative regulation of axon extension IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0048681 negative regulation of axon regeneration IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043198 dendritic shaft IEA
 cellular_componentGO:0044295 axonal growth cone IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0035374 chondroitin sulfate binding IEA
 molecular_functionGO:0038131 neuregulin receptor activity IEA


Pathways (from Reactome)
Pathway description
Axonal growth inhibition (RHOA activation)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002708 LINGO1 / Q50L44 / Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 / Q9D1T0* / Q96FE5* / leucine rich repeat and Ig domain containing 1*  / reaction / complex
 ENSGALG00000035950 NGFR / P18519 / Tumor necrosis factor receptor superfamily member 16 / P08138* / nerve growth factor receptor*  / reaction / complex
 ENSGALG00000008443 ARHGDIA / rho GDP-dissociation inhibitor 1 / P52565* / Q99PT1* / Rho GDP dissociation inhibitor alpha*  / reaction / complex
 ENSGALG00000005594 OMG / oligodendrocyte myelin glycoprotein / P23515*  / reaction / complex
 ENSGALG00000007732 RTN4R* / Q99PI8* / Q9BZR6* / reticulon 4 receptor*  / -






 

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