ENSGALG00000007767


Gallus gallus

Features
Gene ID: ENSGALG00000007767
  
Biological name :DIS3L2
  
Synonyms : DIS3L2 / DIS3 like 3-5 exoribonuclease 2
  
Possible biological names infered from orthology : DIS3-like exonuclease 2 / Q8CI75 / Q8IYB7
  
Species: Gallus gallus
  
Chr. number: 9
Strand: 1
Band:
Gene start: 15449856
Gene end: 15613805
  
Corresponding Affymetrix probe sets: GgaAffx.4840.1.S1_at (Chicken Array)   GgaAffx.4840.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012585
Ensembl peptide - ENSGALP00000050872
Ensembl peptide - ENSGALP00000049171
Ensembl peptide - ENSGALP00000047456
NCBI entrez gene - 424934     See in Manteia.
RefSeq - XM_015291462
swissprot - E1C372
swissprot - A0A1D5PDM7
swissprot - A0A1D5P8X2
swissprot - A0A1D5P450
Ensembl - ENSGALG00000007767
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dis3l2ENSDARG00000033259Danio rerio
 DIS3L2ENSG00000144535Homo sapiens
 Dis3l2ENSMUSG00000053333Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DIS3L / DIS3 like exosome 3-5 exoribonuclease / Q8C0S1* / Q8TF46* / DIS3-like exonuclease 1 *ENSGALG0000000764328
DIS3 / DIS3 homolog, exosome endoribonuclease and 3-5 exoribonuclease / Q9CSH3* / Q9Y2L1* / Exosome complex exonuclease RRP44 *ENSGALG0000001693028


Protein motifs (from Interpro)
Interpro ID Name
 IPR012340  Nucleic acid-binding, OB-fold
 IPR022966  Ribonuclease II/R, conserved site
 IPR028591  DIS3-like exonuclease 2
 IPR033771  Rrp44-like cold shock domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic IEA
 biological_processGO:0006364 rRNA processing IBA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010587 miRNA catabolic process IEA
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3"-5" IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051306 mitotic sister chromatid separation IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 biological_processGO:1990074 polyuridylation-dependent mRNA catabolic process IEA
 cellular_componentGO:0000178 exosome (RNase complex) IBA
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000175 3"-5"-exoribonuclease activity IBA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0004540 ribonuclease activity IEA
 molecular_functionGO:0008266 poly(U) RNA binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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