ENSDARG00000033259


Danio rerio

Features
Gene ID: ENSDARG00000033259
  
Biological name :dis3l2
  
Synonyms : dis3l2 / DIS3 like 3-5 exoribonuclease 2
  
Possible biological names infered from orthology : DIS3-like exonuclease 2 / Q8CI75 / Q8IYB7
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 5841108
Gene end: 5884404
  
Corresponding Affymetrix probe sets: Dr.16799.1.A1_at (Zebrafish Array)   Dr.7984.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000114941
Ensembl peptide - ENSDARP00000149486
NCBI entrez gene - 566106     See in Manteia.
swissprot - E7F350
ZFIN ID - ZDB-GENE-070705-171
Ensembl - ENSDARG00000033259
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DIS3L2ENSGALG00000007767Gallus gallus
 DIS3L2ENSG00000144535Homo sapiens
 Dis3l2ENSMUSG00000053333Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dis3 / DIS3 exosome endoribonuclease and 3-5 exoribonuclease / Q9CSH3* / Q9Y2L1* / Exosome complex exonuclease RRP44 * / DIS3 homolog, exosome endoribonuclease and 3-5 exoribonuclease*ENSDARG0000006055925
dis3l / DIS3 like exosome 3-5 exoribonuclease / Q8C0S1* / Q8TF46* / DIS3-like exonuclease 1 *ENSDARG0000005320024


Protein motifs (from Interpro)
Interpro ID Name
 IPR012340  Nucleic acid-binding, OB-fold
 IPR022966  Ribonuclease II/R, conserved site
 IPR028591  DIS3-like exonuclease 2
 IPR033771  Rrp44-like cold shock domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic IEA
 biological_processGO:0006364 rRNA processing IBA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010587 miRNA catabolic process IEA
 biological_processGO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3"-5" IEA
 biological_processGO:0048793 pronephros development IMP
 biological_processGO:0051301 cell division IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 biological_processGO:1990074 polyuridylation-dependent mRNA catabolic process IEA
 cellular_componentGO:0000178 exosome (RNase complex) IBA
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000175 3"-5"-exoribonuclease activity IBA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0001055 pronephric duct opening pronephric duct opening morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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