ENSGALG00000008094


Gallus gallus

Features
Gene ID: ENSGALG00000008094
  
Biological name :HSPD1
  
Synonyms : 60 kDa heat shock protein, mitochondrial / HSPD1 / Q5ZL72
  
Possible biological names infered from orthology : heat shock protein 1 (chaperonin) / heat shock protein family D (Hsp60) member 1 / P10809 / P63038
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 10239404
Gene end: 10248714
  
Corresponding Affymetrix probe sets: Gga.9897.1.S1_at (Chicken Array)   GgaAffx.11965.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013122
NCBI entrez gene - 424059     See in Manteia.
RefSeq - NM_001012916
RefSeq Peptide - NP_001012934
swissprot - Q5ZL72
Ensembl - ENSGALG00000008094
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hspd1ENSDARG00000056160Danio rerio
 HSPD1ENSG00000144381Homo sapiens
 Hspd1ENSMUSG00000025980Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001844  Chaperonin Cpn60
 IPR002423  Chaperonin Cpn60/TCP-1 family
 IPR018370  Chaperonin Cpn60, conserved site
 IPR027409  GroEL-like apical domain superfamily
 IPR027413  GroEL-like equatorial domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001817 regulation of cytokine production IBA
 biological_processGO:0002368 B cell cytokine production IEA
 biological_processGO:0002755 MyD88-dependent toll-like receptor signaling pathway IEA
 biological_processGO:0002842 positive regulation of T cell mediated immune response to tumor cell IEA
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006458 "de novo" protein folding IBA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0008637 apoptotic mitochondrial changes IBA
 biological_processGO:0009409 response to cold IDA
 biological_processGO:0032727 positive regulation of interferon-alpha production IEA
 biological_processGO:0032729 positive regulation of interferon-gamma production IEA
 biological_processGO:0032733 positive regulation of interleukin-10 production IEA
 biological_processGO:0032735 positive regulation of interleukin-12 production IEA
 biological_processGO:0032755 positive regulation of interleukin-6 production IEA
 biological_processGO:0042026 protein refolding IEA
 biological_processGO:0042100 B cell proliferation IEA
 biological_processGO:0042110 T cell activation IEA
 biological_processGO:0042113 B cell activation IEA
 biological_processGO:0043032 positive regulation of macrophage activation IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045041 protein import into mitochondrial intermembrane space IBA
 biological_processGO:0048291 isotype switching to IgG isotypes IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0050870 positive regulation of T cell activation IEA
 biological_processGO:0051702 interaction with symbiont IEA
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion IBA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex IEA
 cellular_componentGO:0030135 coated vesicle IEA
 cellular_componentGO:0030141 secretory granule IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0046696 lipopolysaccharide receptor complex IEA
 cellular_componentGO:0070062 extracellular exosome IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0001530 lipopolysaccharide binding IEA
 molecular_functionGO:0002039 p53 binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008035 high-density lipoprotein particle binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0034185 apolipoprotein binding IEA
 molecular_functionGO:0034186 apolipoprotein A-I binding IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IBA
 molecular_functionGO:0051082 unfolded protein binding IBA
 molecular_functionGO:0051087 chaperone binding IEA


Pathways (from Reactome)
Pathway description
Mitochondrial protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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