ENSGALG00000008569


Gallus gallus

Features
Gene ID: ENSGALG00000008569
  
Biological name :CHP1
  
Synonyms : Calcineurin B homologous protein 1 / CHP1 / Q5ZM44
  
Possible biological names infered from orthology : calcineurin like EF-hand protein 1 / P61022 / Q99653
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 24528083
Gene end: 24545033
  
Corresponding Affymetrix probe sets: Gga.16756.1.S1_at (Chicken Array)   Gga.16756.1.S1_s_at (Chicken Array)   GgaAffx.11643.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000032005
Ensembl peptide - ENSGALP00000056837
NCBI entrez gene - 423211     See in Manteia.
RefSeq - NM_001007930
RefSeq - XM_015287067
RefSeq Peptide - NP_001007931
swissprot - Q5ZM44
Ensembl - ENSGALG00000008569
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chp1ENSDARG00000052859Danio rerio
 CHP1ENSG00000187446Homo sapiens
 Chp1ENSMUSG00000014077Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPP3R1 / Ppp3r2* / Q63811* / AC017083.3* / protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II)*ENSGALG0000002364835
TESC / calcineurin B homologous protein 3 / Tescl* / Q9JKL5* / Q96BS2* / tescalcin*ENSGALG0000000820626


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001578 microtubule bundle formation ISS
 biological_processGO:0001933 negative regulation of protein phosphorylation ISS
 biological_processGO:0006469 negative regulation of protein kinase activity ISS
 biological_processGO:0006611 protein export from nucleus ISS
 biological_processGO:0010923 negative regulation of phosphatase activity ISS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0022406 membrane docking ISS
 biological_processGO:0031122 cytoplasmic microtubule organization ISS
 biological_processGO:0031397 negative regulation of protein ubiquitination ISS
 biological_processGO:0031953 negative regulation of protein autophosphorylation ISS
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity ISS
 biological_processGO:0032417 positive regulation of sodium:proton antiporter activity ISS
 biological_processGO:0042308 negative regulation of protein import into nucleus ISS
 biological_processGO:0050821 protein stabilization IDA
 biological_processGO:0051222 positive regulation of protein transport ISS
 biological_processGO:0051453 regulation of intracellular pH ISS
 biological_processGO:0060050 positive regulation of protein glycosylation ISS
 biological_processGO:0061024 membrane organization ISS
 biological_processGO:0061025 membrane fusion ISS
 biological_processGO:0070885 negative regulation of calcineurin-NFAT signaling cascade ISS
 biological_processGO:0071468 cellular response to acidic pH IDA
 biological_processGO:0090314 positive regulation of protein targeting to membrane IDA
 biological_processGO:1901214 regulation of neuron death IEA
 cellular_componentGO:0000139 Golgi membrane ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0015630 microtubule cytoskeleton ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030133 transport vesicle ISS
 molecular_functionGO:0004860 protein kinase inhibitor activity IEA
 molecular_functionGO:0005215 transporter activity ISS
 molecular_functionGO:0005509 calcium ion binding ISS
 molecular_functionGO:0008017 microtubule binding ISS
 molecular_functionGO:0019900 kinase binding ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding ISS


Pathways (from Reactome)
Pathway description
Hyaluronan uptake and degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000042009 HMMR / hyaluronan mediated motility receptor / O75330* / Q00547*  / reaction / complex
 ENSGALG00000039080 CD44 / CD44 molecule (Indian blood group) / P16070*  / reaction / complex
 ENSGALG00000005643 LYVE1 / lymphatic vessel endothelial hyaluronan receptor 1 / Q8BHC0* / Q9Y5Y7* / Lymphatic vessel endothelial hyaluronic acid receptor 1 *  / complex / reaction
 ENSGALG00000002138 HYAL2 / hyaluronoglucosaminidase 2 / O35632* / Q12891* / Hyaluronidase-2 *  / complex / reaction






 

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