ENSGALG00000039080


Gallus gallus

Features
Gene ID: ENSGALG00000039080
  
Biological name :CD44
  
Synonyms : CD44 / CD44 molecule (Indian blood group)
  
Possible biological names infered from orthology : P16070
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 18956776
Gene end: 19014765
  
Corresponding Affymetrix probe sets: Gga.19452.1.S1_at (Chicken Array)   Gga.3572.1.S1_at (Chicken Array)   Gga.3572.1.S2_at (Chicken Array)   Gga.3572.1.S2_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050161
Ensembl peptide - ENSGALP00000056897
NCBI entrez gene - 395666     See in Manteia.
RefSeq - XM_015286974
RefSeq - XM_015286968
RefSeq - XM_015286969
RefSeq - XM_015286973
RefSeq - NM_204860
RefSeq - XM_015286944
RefSeq - XM_015286945
RefSeq - XM_015286946
RefSeq - XM_015286947
RefSeq - XM_015286948
RefSeq - XM_015286949
RefSeq - XM_015286950
RefSeq - XM_015286951
RefSeq - XM_015286952
RefSeq - XM_015286953
RefSeq - XM_015286954
RefSeq - XM_015286955
RefSeq - XM_015286956
RefSeq - XM_015286958
RefSeq - XM_015286959
RefSeq - XM_015286960
RefSeq - XM_015286961
RefSeq - XM_015286962
RefSeq - XM_015286963
RefSeq - XM_015286964
RefSeq - XM_015286965
RefSeq - XM_015286966
RefSeq - XM_015286967
RefSeq Peptide - NP_990191
swissprot - A0A1D5PVD2
swissprot - A0A1D5PBN1
Ensembl - ENSGALG00000039080
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cd44aENSDARG00000087863Danio rerio
 cd44bENSDARG00000089892Danio rerio
 CD44ENSG00000026508Homo sapiens
 Cd44ENSMUSG00000005087Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LYVE1 / lymphatic vessel endothelial hyaluronan receptor 1 / Q8BHC0* / Q9Y5Y7* / Lymphatic vessel endothelial hyaluronic acid receptor 1 *ENSGALG000000056439


Protein motifs (from Interpro)
Interpro ID Name
 IPR000538  Link domain
 IPR001231  CD44 antigen
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0030214 hyaluronan catabolic process IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0034116 positive regulation of heterotypic cell-cell adhesion IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator IEA
 biological_processGO:0044319 wound healing, spreading of cells IEA
 biological_processGO:0044344 cellular response to fibroblast growth factor stimulus IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0051216 cartilage development IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0070487 monocyte aggregation IEA
 biological_processGO:1900625 positive regulation of monocyte aggregation IEA
 biological_processGO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
 biological_processGO:2000392 regulation of lamellipodium morphogenesis IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0031258 lamellipodium membrane IEA
 cellular_componentGO:0035692 macrophage migration inhibitory factor receptor complex IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA
 molecular_functionGO:0005540 hyaluronic acid binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Hyaluronan uptake and degradation
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008569 CHP1 / Q5ZM44 / Calcineurin B homologous protein 1 / P61022* / Q99653* / calcineurin like EF-hand protein 1*  / complex / reaction
 ENSGALG00000002138 HYAL2 / hyaluronoglucosaminidase 2 / O35632* / Q12891* / Hyaluronidase-2 *  / complex / reaction
 ENSGALG00000006992 MMP9 / matrix metalloproteinase-9 precursor / P14780* / P41245* / matrix metallopeptidase 9* / Matrix metalloproteinase-9 *  / reaction / complex
 ENSGALG00000003580 MMP2 / Q90611 / 72 kDa type IV collagenase / P08253* / P33434* / matrix metallopeptidase 2* / 72 kDa type IV collagenase PEX*  / reaction / complex
 ENSGALG00000039080 CD44 / CD44 molecule (Indian blood group) / P16070*  / reaction / complex






 

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