ENSGALG00000009050


Gallus gallus

Features
Gene ID: ENSGALG00000009050
  
Biological name :CAPN3
  
Synonyms : calpain 3 / CAPN3
  
Possible biological names infered from orthology : P20807 / Q64691
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 25645574
Gene end: 25669788
  
Corresponding Affymetrix probe sets: Gga.72.1.S1_at (Chicken Array)   Gga.72.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000031999
Ensembl peptide - ENSGALP00000060944
Ensembl peptide - ENSGALP00000053715
NCBI entrez gene - 423233     See in Manteia.
RefSeq - NM_001004405
RefSeq - XM_015287074
RefSeq - XM_015287075
RefSeq Peptide - NP_001004405
swissprot - A0A1L1RQ67
swissprot - A0A1D5PLJ8
swissprot - F1NJ45
Ensembl - ENSGALG00000009050
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 capn3aENSDARG00000041864Danio rerio
 capn3bENSDARG00000043035Danio rerio
 CAPN3ENSG00000092529Homo sapiens
 Capn3ENSMUSG00000079110Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CAPN11 / P00789 / Calpain-1 catalytic subunit / Q6J756* / Q9UMQ6* / calpain 11*ENSGALG0000001018647
CAPN2 / calpain-2 catalytic subunit precursor / O08529* / P17655* / calpain 2* / Calpain-2 catalytic subunit *ENSGALG0000000936044
CAPN14 / calpain 14 / A8MX76*ENSGALG0000000906932
CAPN13 / calpain 13 / Q3UW68* / Q6MZZ7*ENSGALG0000002008429
CAPN5 / calpain 5 / O08688* / O15484*ENSGALG0000004047828
CAPN6 / calpain 6 / O35646* / Q9Y6Q1*ENSGALG0000000800626
CAPN8 / calpain 8 / A6NHC0* / Q91VA3*ENSGALG0000000938221


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR001300  Peptidase C2, calpain, catalytic domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR022682  Peptidase C2, calpain, large subunit, domain III
 IPR022683  Peptidase C2, calpain, domain III
 IPR022684  Peptidase C2, calpain family
 IPR029531  Calpain-3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0012501 programmed cell death IEA
 biological_processGO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration IEA
 biological_processGO:0030239 myofibril assembly IEA
 biological_processGO:0033234 negative regulation of protein sumoylation IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0045214 sarcomere organization IEA
 biological_processGO:0045661 regulation of myoblast differentiation IEA
 biological_processGO:0045862 positive regulation of proteolysis IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IEA
 biological_processGO:0061061 muscle structure development IEA
 biological_processGO:0065003 protein-containing complex assembly IEA
 biological_processGO:0070315 G1 to G0 transition involved in cell differentiation IEA
 biological_processGO:0071277 cellular response to calcium ion IEA
 biological_processGO:0071472 cellular response to salt stress IEA
 biological_processGO:0072657 protein localization to membrane IEA
 biological_processGO:0097264 self proteolysis IEA
 biological_processGO:2001015 negative regulation of skeletal muscle cell differentiation IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004198 calcium-dependent cysteine-type endopeptidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0008307 structural constituent of muscle IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0031402 sodium ion binding IEA
 molecular_functionGO:0031432 titin binding IEA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA
 molecular_functionGO:0055103 ligase regulator activity IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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