ENSGALG00000009360


Gallus gallus

Features
Gene ID: ENSGALG00000009360
  
Biological name :CAPN2
  
Synonyms : calpain-2 catalytic subunit precursor / CAPN2
  
Possible biological names infered from orthology : calpain 2 / Calpain-2 catalytic subunit / O08529 / P17655
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 17691064
Gene end: 17711286
  
Corresponding Affymetrix probe sets: Gga.3677.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000015229
Ensembl peptide - ENSGALP00000048951
NCBI entrez gene - 395963     See in Manteia.
RefSeq - NM_205080
RefSeq Peptide - NP_990411
swissprot - E1BR22
swissprot - A0A1D5P8A6
Ensembl - ENSGALG00000009360
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 capn2aENSDARG00000091699Danio rerio
 capn2bENSDARG00000055592Danio rerio
 zgc:92480ENSDARG00000034211Danio rerio
 CAPN2ENSG00000162909Homo sapiens
 Capn2ENSMUSG00000026509Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CAPN11 / P00789 / Calpain-1 catalytic subunit / Q6J756* / Q9UMQ6* / calpain 11*ENSGALG0000001018663
CAPN3 / calpain 3 / P20807* / Q64691*ENSGALG0000000905050
CAPN14 / calpain 14 / A8MX76*ENSGALG0000000906938
CAPN8 / calpain 8 / A6NHC0* / Q91VA3*ENSGALG0000000938234
CAPN13 / calpain 13 / Q3UW68* / Q6MZZ7*ENSGALG0000002008433
CAPN5 / calpain 5 / O08688* / O15484*ENSGALG0000004047830
CAPN6 / calpain 6 / O35646* / Q9Y6Q1*ENSGALG0000000800629


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR001300  Peptidase C2, calpain, catalytic domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR022682  Peptidase C2, calpain, large subunit, domain III
 IPR022683  Peptidase C2, calpain, domain III
 IPR022684  Peptidase C2, calpain family
 IPR029539  Calpain-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001824 blastocyst development IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007520 myoblast fusion IEA
 biological_processGO:0051493 regulation of cytoskeleton organization IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IEA
 biological_processGO:0071230 cellular response to amino acid stimulus IEA
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0031143 pseudopodium IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0097038 perinuclear endoplasmic reticulum IEA
 molecular_functionGO:0004198 calcium-dependent cysteine-type endopeptidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:1990782 protein tyrosine kinase binding IPI


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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