ENSGALG00000009096


Gallus gallus

Features
Gene ID: ENSGALG00000009096
  
Biological name :MTM1
  
Synonyms : MTM1 / myotubularin 1
  
Possible biological names infered from orthology : Q13496 / Q9Z2C5 / X-linked myotubular myopathy gene 1
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 17820524
Gene end: 17851478
  
Corresponding Affymetrix probe sets: Gga.12543.1.S1_at (Chicken Array)   Gga.6915.1.A1_at (Chicken Array)   GgaAffx.22799.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014791
Ensembl peptide - ENSGALP00000057910
NCBI entrez gene - 422388     See in Manteia.
RefSeq - XM_004940860
RefSeq - XM_015278650
RefSeq - XM_420357
swissprot - E1BRL5
swissprot - A0A1D5PY61
Ensembl - ENSGALG00000009096
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtm1ENSDARG00000037560Danio rerio
 MTM1ENSG00000171100Homo sapiens
 Mtm1ENSMUSG00000031337Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MTMR2 / Q5ZIV1 / Myotubularin-related protein 2 / Q13614* / Q9Z2D1*ENSGALG0000001720063
MTMR1 / myotubularin related protein 1 / Q13613* / Q9Z2C4*ENSGALG0000000908558
MTMR4 / myotubularin related protein 4 / Q91XS1* / Q9NYA4* / Mus musculus myotubularin related protein 4 (Mtmr4), transcript variant 2, mRNA.*ENSGALG0000000104233
MTMR8 / myotubularin-related protein 8 / Q96EF0*ENSGALG0000000759032
MTMR3 / myotubularin related protein 3 / Q13615*ENSGALG0000000805131
MTMR6 / myotubularin related protein 6 / Q8VE11* / Q9Y217*ENSGALG0000001711230
MTMR9 / myotubularin-related protein 9 / Q96QG7* / Q9Z2D0*ENSGALG0000001664926
SBF2 / SET binding factor 2 / Q86WG5*ENSGALG0000000571624
ENSGALG0000000331323
SBF1 / SET binding factor 1 / O95248* / Q6ZPE2*ENSGALG0000004317823
MTMR7* / Q9Y216* / Q9Z2C9* / myotubularin related protein 7*ENSGALG0000003602115
MTMR7* / Q9Y216* / Q9Z2C9* / myotubularin related protein 7*ENSGALG000000136411


Protein motifs (from Interpro)
Interpro ID Name
 IPR004182  GRAM domain
 IPR010569  Myotubularin-like phosphatase domain
 IPR011993  PH-like domain superfamily
 IPR029021  Protein-tyrosine phosphatase-like
 IPR030564  Myotubularin family
 IPR030587  Myotubularin-related protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0008333 endosome to lysosome transport IEA
 biological_processGO:0032007 negative regulation of TOR signaling IEA
 biological_processGO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0044088 regulation of vacuole organization IEA
 biological_processGO:0045109 intermediate filament organization IEA
 biological_processGO:0046716 muscle cell cellular homeostasis IEA
 biological_processGO:0046856 phosphatidylinositol dephosphorylation IEA
 biological_processGO:0048311 mitochondrion distribution IEA
 biological_processGO:0048633 positive regulation of skeletal muscle tissue growth IEA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IEA
 biological_processGO:0070584 mitochondrion morphogenesis IEA
 biological_processGO:1902902 negative regulation of autophagosome assembly IEA
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0031674 I band IEA
 molecular_functionGO:0004438 phosphatidylinositol-3-phosphatase activity IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0019215 intermediate filament binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA
 molecular_functionGO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane
Synthesis of PIPs at the early endosome membrane
Synthesis of PIPs at the late endosome membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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