ENSGALG00000010572


Gallus gallus

Features
Gene ID: ENSGALG00000010572
  
Biological name :TSHR
  
Synonyms : thyrotropin receptor isoform 2 precursor / TSHR
  
Possible biological names infered from orthology : P16473 / P47750 / thyroid stimulating hormone receptor
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 40811286
Gene end: 40858950
  
Corresponding Affymetrix probe sets: GgaAffx.6682.1.S1_at (Chicken Array)   GgaAffx.6682.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000036865
Ensembl peptide - ENSGALP00000017185
Ensembl peptide - ENSGALP00000036864
NCBI entrez gene - 428900     See in Manteia.
RefSeq - NM_001033850
RefSeq - NM_001193589
RefSeq - NM_001193588
RefSeq Peptide - NP_001180518
RefSeq Peptide - NP_001029022
RefSeq Peptide - NP_001180517
swissprot - F1NKT4
swissprot - F1NTD1
swissprot - F1NTD0
Ensembl - ENSGALG00000010572
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tshrENSDARG00000037195Danio rerio
 TSHRENSG00000165409Homo sapiens
 TshrENSMUSG00000020963Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FSHR / follicle-stimulating hormone receptor precursor / P23945* / P35378* / follicle stimulating hormone receptor*ENSGALG0000000910048
LHCGR / lutropin-choriogonadotropic hormone receptor precursor / P30730* / P22888* / AC073082.1* / Lutropin-choriogonadotropic hormone receptor * / luteinizing hormone/choriogonadotropin receptor*ENSGALG0000000909548
LGR5 / leucine rich repeat containing G protein-coupled receptor 5 / O75473* / Q9Z1P4*ENSGALG0000001016323
LGR4 / leucine rich repeat containing G protein-coupled receptor 4 / A2ARI4* / Q9BXB1*ENSGALG0000004083421
RXFP1 / relaxin/insulin like family peptide receptor 1 / Q6R6I7* / Q9HBX9* / Relaxin receptor 1 *ENSGALG0000000942919
ENSGALG0000002976417
LGR6 / leucine rich repeat containing G protein-coupled receptor 6 / Q3UVD5* / Q9HBX8*ENSGALG000000005684


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR002131  Glycoprotein hormone receptor family
 IPR002274  Thyrotropin receptor
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR026906  Leucine rich repeat 5
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007190 activation of adenylate cyclase activity IBA
 biological_processGO:0007399 nervous system development IBA
 biological_processGO:0008344 adult locomotory behavior IEA
 biological_processGO:0009755 hormone-mediated signaling pathway IBA
 biological_processGO:0030183 B cell differentiation IEA
 biological_processGO:0038194 thyroid-stimulating hormone signaling pathway IEA
 biological_processGO:0040012 regulation of locomotion IEA
 biological_processGO:0040018 positive regulation of multicellular organism growth IEA
 biological_processGO:0060119 inner ear receptor cell development IEA
 biological_processGO:0060122 inner ear receptor cell stereocilium organization IEA
 biological_processGO:0071542 dopaminergic neuron differentiation IEA
 biological_processGO:0090103 cochlea morphogenesis IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004996 thyroid-stimulating hormone receptor activity IEA
 molecular_functionGO:0008528 G-protein coupled peptide receptor activity IBA
 molecular_functionGO:0016500 protein-hormone receptor activity IEA


Pathways (from Reactome)
Pathway description
Hormone ligand-binding receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002550 TSHB / O57340 / Thyrotropin subunit beta / P01222* / thyroid stimulating hormone beta* / thyroid stimulating hormone, beta subunit*  / reaction / complex
 ENSGALG00000015824 CGA / glycoprotein hormones, alpha polypeptide / P01215* / P01216* / Glycoprotein hormones alpha chain *  / reaction / complex






 

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