ENSGALG00000010943


Gallus gallus

Features
Gene ID: ENSGALG00000010943
  
Biological name :SCN1A
  
Synonyms : SCN1A / sodium voltage-gated channel alpha subunit 1
  
Possible biological names infered from orthology : A2APX8 / P35498 / Sodium channel protein type 1 subunit alpha
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 19691055
Gene end: 19747676
  
Corresponding Affymetrix probe sets: GgaAffx.6995.1.S1_s_at (Chicken Array)   GgaAffx.6995.2.S1_at (Chicken Array)   GgaAffx.6995.8.S1_s_at (Chicken Array)   GgaAffx.6995.9.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017793
Ensembl peptide - ENSGALP00000055471
Ensembl peptide - ENSGALP00000051828
NCBI entrez gene - 771555     See in Manteia.
RefSeq - XM_015289739
RefSeq - XM_004942781
RefSeq - XM_015289737
RefSeq - XM_015289738
RefSeq - XM_001233838
RefSeq - XM_003641586
RefSeq - XM_003641587
RefSeq - XM_004942779
swissprot - E1C4R5
swissprot - A0A1D5PRE7
swissprot - A0A1D5PGA7
Ensembl - ENSGALG00000010943
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scn1aENSDARG00000086819Danio rerio
 scn1labENSDARG00000062744Danio rerio
 SCN1AENSG00000144285Homo sapiens
 Scn1aENSMUSG00000064329Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SCN2A / sodium voltage-gated channel alpha subunit 2 / Q99250* / sodium channel, voltage-gated, type II, alpha*ENSGALG0000001100989
SCN3A / sodium voltage-gated channel alpha subunit 3 / Q9NY46* / sodium channel, voltage-gated, type III, alpha*ENSGALG0000001104085
SCN9A / sodium channel protein type 9 subunit alpha / SCN7A* / Q62205* / Q15858* / Q01118* / sodium voltage-gated channel alpha subunit 7* / sodium voltage-gated channel alpha subunit 9*ENSGALG0000002779380
SCN8A / sodium voltage-gated channel alpha subunit 8 / Q9UQD0* / sodium channel, voltage-gated, type VIII, alpha*ENSGALG0000004372876
SCN5A / Gallus gallus sodium voltage-gated channel alpha subunit 5 (SCN5A), mRNA. / Q9JJV9* / Q14524* / Sodium channel protein type 5 subunit alpha * / sodium voltage-gated channel alpha subunit 5*ENSGALG0000000611266
SCN4A / Gallus gallus sodium voltage-gated channel alpha subunit 4 (SCN4A), mRNA. / P35499* / sodium voltage-gated channel alpha subunit 4* / sodium channel, voltage-gated, type IV, alpha*ENSGALG0000003442760
ENSGALG0000000607258
SCN11A / Gallus gallus sodium voltage-gated channel alpha subunit 11 (SCN11A), mRNA. / Q9UI33* / Q9R053* / Sodium channel protein type 11 subunit alpha * / sodium voltage-gated channel alph...ENSGALG0000002770249
CACNA1G / calcium voltage-gated channel subunit alpha1 G / O43497* / calcium channel, voltage-dependent, T type, alpha 1G subunit*ENSGALG0000000762324
CACNA1I / calcium voltage-gated channel subunit alpha1 I / Q9P0X4* / calcium channel, voltage-dependent, alpha 1I subunit*ENSGALG0000003505123
CACNA1H / calcium voltage-gated channel subunit alpha1 H / O95180* / voltage-dependent T-type calcium channel subunit alpha-1H isoform 2 *ENSGALG0000000521518


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001696  Voltage gated sodium channel, alpha subunit
 IPR005821  Ion transport domain
 IPR008051  Voltage gated sodium channel, alpha-1 subunit
 IPR010526  Sodium ion transport-associated
 IPR024583  Voltage-gated Na+ ion channel, cytoplasmic domain
 IPR027359  Voltage-dependent channel domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001508 action potential IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0007628 adult walking behavior IEA
 biological_processGO:0019227 neuronal action potential propagation IEA
 biological_processGO:0019228 neuronal action potential IBA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0050884 neuromuscular process controlling posture IEA
 biological_processGO:0050966 detection of mechanical stimulus involved in sensory perception of pain IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0086002 cardiac muscle cell action potential involved in contraction IEA
 biological_processGO:0086010 membrane depolarization during action potential IBA
 cellular_componentGO:0001518 voltage-gated sodium channel complex IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014704 intercalated disc IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0030315 T-tubule IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0033268 node of Ranvier IEA
 cellular_componentGO:0034706 sodium channel complex IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043194 axon initial segment IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005248 voltage-gated sodium channel activity IEA
 molecular_functionGO:0005272 sodium channel activity IEA


Pathways (from Reactome)
Pathway description
Phase 0 - rapid depolarisation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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