ENSGALG00000011094


Gallus gallus

Features
Gene ID: ENSGALG00000011094
  
Biological name :PDE4B
  
Synonyms : cAMP-specific 3,5-cyclic phosphodiesterase 4B / PDE4B
  
Possible biological names infered from orthology : phosphodiesterase 4B / phosphodiesterase 4B, cAMP specific / Q07343
  
Species: Gallus gallus
  
Chr. number: 8
Strand: 1
Band:
Gene start: 28602386
Gene end: 28623532
  
Corresponding Affymetrix probe sets: Gga.19233.1.S1_s_at (Chicken Array)   GgaAffx.12121.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018052
NCBI entrez gene - 424700     See in Manteia.
RefSeq - XM_015291032
RefSeq - NM_001031291
RefSeq - XM_015291030
RefSeq - XM_015291031
RefSeq Peptide - NP_001026462
swissprot - F1NDU5
Ensembl - ENSGALG00000011094
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pde4baENSDARG00000032868Danio rerio
 pde4bbENSDARG00000074233Danio rerio
 PDE4BENSG00000184588Homo sapiens
 Pde4bENSMUSG00000028525Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDE4D / phosphodiesterase 4D / Q01063* / Q08499* / cAMP-specific 3,5-cyclic phosphodiesterase 4D *ENSGALG0000001472776
PDE4C* / Q08493* / Q3UEI1* / AC008397.2* / phosphodiesterase 4C* / cAMP-specific 3,5-cyclic phosphodiesterase 4C *ENSGALG0000003702970
PDE1C / phosphodiesterase 1C / Q14123* / Q64338*ENSGALG0000003993528
PDE1A / phosphodiesterase 1A / P54750* / phosphodiesterase 1A, calmodulin-dependent*ENSGALG0000000888526
PDE8B* / O95263* / E9Q4S1* / AC022414.1* / phosphodiesterase 8B* / High affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8B * / high affinity cAMP-specific and IBMX-...ENSGALG0000000433925
PDE8A / phosphodiesterase 8A / O60658* / O88502* / High affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8A *ENSGALG0000000599223
PDE7B / phosphodiesterase 7B / Q9NP56* / Q9QXQ1* / cAMP-specific 3,5-cyclic phosphodiesterase 7B *ENSGALG0000001394122
PDE7A / phosphodiesterase 7A / P70453* / Q13946* / High affinity cAMP-specific 3,5-cyclic phosphodiesterase 7A *ENSGALG0000003839521


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003607  HD/PDEase domain
 IPR023088  3"5"-cyclic nucleotide phosphodiesterase
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001780 neutrophil homeostasis IEA
 biological_processGO:0006198 cAMP catabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0030593 neutrophil chemotaxis IEA
 biological_processGO:0032729 positive regulation of interferon-gamma production IEA
 biological_processGO:0032743 positive regulation of interleukin-2 production IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0050852 T cell receptor signaling pathway IEA
 biological_processGO:0050900 leukocyte migration IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 cellular_componentGO:0000930 gamma-tubulin complex IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0060076 excitatory synapse IEA
 cellular_componentGO:0071944 cell periphery IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0004115 3",5"-cyclic-AMP phosphodiesterase activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030552 cAMP binding IEA
 molecular_functionGO:0043015 gamma-tubulin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
DARPP-32 events
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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