ENSGALG00000011274


Gallus gallus

Features
Gene ID: ENSGALG00000011274
  
Biological name :DCN
  
Synonyms : DCN / decorin precursor
  
Possible biological names infered from orthology : decorin / P07585 / P28654
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 44019260
Gene end: 44058954
  
Corresponding Affymetrix probe sets: Gga.1719.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018373
Ensembl peptide - ENSGALP00000064214
Ensembl peptide - ENSGALP00000063443
Ensembl peptide - ENSGALP00000062069
NCBI entrez gene - 417892     See in Manteia.
RefSeq - NM_001030747
RefSeq Peptide - NP_001025918
swissprot - E1BRE9
swissprot - A0A1L1RZC0
swissprot - A0A1L1RX77
swissprot - A0A1L1RTD1
Ensembl - ENSGALG00000011274
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dcnENSDARG00000012066Danio rerio
 DCNENSG00000011465Homo sapiens
 DcnENSMUSG00000019929Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASPN / asporin / Q99MQ4* / Q9BXN1*ENSGALG0000000472252
PRELP / proline and arginine rich end leucine rich repeat protein / P51888* / Q9JK53* / proline arginine-rich end leucine-rich repeat*ENSGALG0000003445628
FMOD / fibromodulin precursor / P50608* / Q06828* / fibromodulin*ENSGALG0000003406727
LUM / P51890 / Lumican / P51884* / P51885*ENSGALG0000001127127
ECM2 / extracellular matrix protein 2 / O94769* / Q5FW85*ENSGALG0000000469526
KERA / O42235 / Keratocan / O35367* / O60938*ENSGALG0000001127026
PODN / podocan / Q7TQ62* / Q7Z5L7*ENSGALG0000002186925
OMD / osteomodulin / O35103* / Q99983*ENSGALG0000002608024


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR016352  Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan
 IPR028549  Decorin
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010508 positive regulation of autophagy IEA
 biological_processGO:0010596 negative regulation of endothelial cell migration IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0016239 positive regulation of macroautophagy IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051901 positive regulation of mitochondrial depolarization IEA
 biological_processGO:0090141 positive regulation of mitochondrial fission IEA
 biological_processGO:1900747 negative regulation of vascular endothelial growth factor signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005518 collagen binding IEA
 molecular_functionGO:0005539 glycosaminoglycan binding IEA
 molecular_functionGO:0050840 extracellular matrix binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix
A tetrasaccharide linker sequence is required for GAG synthesis
Chondroitin sulfate biosynthesis
Dermatan sulfate biosynthesis
CS/DS degradation
ECM proteoglycans


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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