ENSMUSG00000019929


Mus musculus

Features
Gene ID: ENSMUSG00000019929
  
Biological name :Dcn
  
Synonyms : Dcn / Decorin / P28654
  
Possible biological names infered from orthology : P07585
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C3
Gene start: 97479609
Gene end: 97518143
  
Corresponding Affymetrix probe sets: 10365974 (MoGene1.0st)   1441506_at (Mouse Genome 430 2.0 Array)   1449368_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000100924
Ensembl peptide - ENSMUSP00000131431
Ensembl peptide - ENSMUSP00000151241
NCBI entrez gene - 13179     See in Manteia.
MGI - MGI:94872
RefSeq - NM_001190451
RefSeq - NM_007833
RefSeq Peptide - NP_001177380
RefSeq Peptide - NP_031859
swissprot - Q3UKR1
swissprot - P28654
swissprot - A0A1W2P6I8
Ensembl - ENSMUSG00000019929
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dcnENSDARG00000012066Danio rerio
 DCNENSGALG00000011274Gallus gallus
 DCNENSG00000011465Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Bgn / P28653 / biglycan / P21810*ENSMUSG0000003137556
Aspn / Q99MQ4 / Asporin / Q9BXN1*ENSMUSG0000002138849
Lum / P51885 / Lumican / P51884*ENSMUSG0000003644630
Prelp / Q9JK53 / proline arginine-rich end leucine-rich repeat / P51888* / proline and arginine rich end leucine rich repeat protein*ENSMUSG0000004157728
Ecm2 / Q5FW85 / Extracellular matrix protein 2 / O94769*ENSMUSG0000004363127
Podn / Q7TQ62 / podocan / Q7Z5L7*ENSMUSG0000002860026
Fmod / P50608 / Fibromodulin / Q06828*ENSMUSG0000004155926
Omd / O35103 / Osteomodulin / Q99983*ENSMUSG0000004836824
Kera / O35367 / Keratocan / O60938*ENSMUSG0000001993224
Podnl1 / Q6P3Y9 / Podocan-like protein 1 / Q6PEZ8* / podocan like 1*ENSMUSG0000001288922


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR016352  Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan
 IPR028549  Decorin
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0001890 placenta development IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0007519 skeletal muscle tissue development IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0009612 response to mechanical stimulus IEA
 biological_processGO:0010508 positive regulation of autophagy ISO
 biological_processGO:0010596 negative regulation of endothelial cell migration ISO
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0016239 positive regulation of macroautophagy ISO
 biological_processGO:0016525 negative regulation of angiogenesis ISO
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan IDA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0051901 positive regulation of mitochondrial depolarization ISO
 biological_processGO:0090141 positive regulation of mitochondrial fission ISO
 biological_processGO:1900747 negative regulation of vascular endothelial growth factor signaling pathway ISO
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005589 collagen type VI trimer IEA
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0031012 extracellular matrix ISO
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005518 collagen binding IEA
 molecular_functionGO:0005539 glycosaminoglycan binding IDA
 molecular_functionGO:0047485 protein N-terminus binding IEA
 molecular_functionGO:0050840 extracellular matrix binding IDA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix
A tetrasaccharide linker sequence is required for GAG synthesis
Chondroitin sulfate biosynthesis
Dermatan sulfate biosynthesis
CS/DS degradation
ECM proteoglycans


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
Show

Allelic Composition: Bgntm1Mfy/Y,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0000519 hydronephrosis "dilation of the pelvis and calices of one or both kidneys" [J:56641]
Show

Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0000619 salivary gland epithelial hyperplasia "increased cell number in the epithelium of the salivary gland" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:63764]
Show

Allelic Composition: MybM303V/MybM303V
Genetic Background: involves: 129S1/SvlmJ * C57BL/6

 MP:0000708 thymus hyperplasia "increased cell number in the thymus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33401]
Show

Allelic Composition: Dcntm1Ioz/Dcntm1Ioz,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

 MP:0000709 enlarged thymus "increased size of thymus" [J:50053]
Show

Allelic Composition: Dcntm1Ioz/Dcntm1Ioz,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

 MP:0001199 thin skin "reduced thickness of the outer protective layer of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471]
Show

Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0001244 thin dermal layer "reduced thickness of the dermis" [J:65030]
Show

Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

Allelic Composition: Bgntm1Mfy/Y,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Bgntm1Mfy/Bgntm1Mfy,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0001800 abnormal humoral immune response "abnormal immune function mediated by antibodies" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Dcntm1Ioz/Dcn+
Genetic Background: either: C.Cg-Dcntm1Ioz or C3.Cg-Dcntm1Ioz

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Bgntm1Mfy/Bgntm1Mfy,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Bgntm1Mfy/Y,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Bgntm1Mfy/Bgntm1Mfy,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0001954 respiratory distress "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
Show

Allelic Composition: Dcntm1Ioz/Dcntm1Ioz,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

Allelic Composition: Dcntm1Ioz/Dcn+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

 MP:0002020 increased tumor incidence "greater than average number of tumors, usually a specific type" [MGI:cls, J:34193]
Show

Allelic Composition: Dcntm1Ioz/Dcntm1Ioz,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

Allelic Composition: Dcntm1Ioz/Dcn+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

 MP:0002024 T cell derived lymphoma "group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Dcntm1Ioz/Dcntm1Ioz,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

Allelic Composition: Dcntm1Ioz/Dcn+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

 MP:0002081 perinatal lethality "death anytime between E18.5 and postnatal day 1 " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Bgntm1Mfy/Y,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: MybM303V/MybM303V
Genetic Background: involves: 129S1/SvlmJ * C57BL/6

Allelic Composition: Dcntm1Ioz/Dcn+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Juptm1Ruiz/Jup+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002294 short gestation period "decrease in the average duration of a pregnancy " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Bgntm1Mfy/Bgntm1Mfy,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0002411 decreased susceptibility to bacterial infection "reduced likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Xab2tm2Tnka/Xab2tm2Tnka
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Dcntm1Ioz/Dcn+
Genetic Background: either: C.Cg-Dcntm1Ioz or C3.Cg-Dcntm1Ioz

 MP:0002704 tubular nephritis "inflammation of the renal tubules" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0002705 dilated renal tubules "enlarged lumens of the loops of Henle and/or collecting ducts of the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0003089 reduced skin tensile strength "reduction in the normal maximum tension the skin can withstand without tearing" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, J:48068]
Show

Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

Allelic Composition: Bgntm1Mfy/Y,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0003215 renal interstitial fibrosis "formation of fibrous tissue within the interstices of the kidney as a result of repair or a reactive process" [RGD:Rat Genome Database submission]
Show

Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0003667 hemangiosarcoma "a malignant tumor characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and appear as irregular blood-filled or lumpy sacs that are typically filled with blood; rupture of the tumor can cause rapid death from bleeding" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:53511]
Show

Allelic Composition: Dcntm1Ioz/Dcntm1Ioz,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

 MP:0003668 abnormal periodontal ligament morphology "any structural anomaly in the fibrous connective tissue that surrounds the root of a tooth, separating it from and attaching it to the alveolar bone; normally extends from the base of the gingival mucosa to the fundus of the bony socket, and its main function is to hold the tooth in its socket" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:66512]
Show

Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0003669 periodontal ligament hypercellularity "increased cell density of the periodontal ligament" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:66512]
Show

Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0003795 abnormal bone structure 
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Allelic Composition: Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0004126 thin hypodermis "reduced thickness of the innermost and thickest layer of the skin composed of loose connective tissue containing adipoctyes" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Bgntm1Mfy/Y,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0004153 increased renal tubule apoptosis "increase in the number of renal tubule cells undergoing programmed cell death" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0004686 decreased length of long bones "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bgntm1Mfy/Y,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0004970 kidney atrophy "wasting of the kidney due to injury or disease, resulting in reduced size" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0005421 loose skin "condition in which the skin hangs in folds" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0005503 abnormal tendon morphology "structural anomaly of the fibrous bands or cords of connective tissue at the ends of muscle fibers that attach muscles to bones and other structures" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:45509]
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Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

Allelic Composition: Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0008151 increased diameter of long bones "increased width of the cross-sectional distance that extends from one lateral edge of a long bone, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bgntm1Mfy/Y,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0008438 abnormal cutaneous collagen fibril morphology "any structural anomaly of the connective tissue bundles in the extracellular matrix of skin tissue that are composed of collagen, and play a role in skin strength and elasticity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

Allelic Composition: Bgntm1Mfy/Y,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0009640 abnormal renal tubule epithelium morphology "any structural anomaly of the cellular avascular layer of the renal tubule luminar surfaces" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0010792 abnormal stomach mucosa morphology "any structural anomaly of the mucous layer of the stomach wall which contains the gastric pits and glands, and consists of epithelium, lamina propria, and the muscularis mucosae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: MybM303V/MybM303V
Genetic Background: involves: 129S1/SvlmJ * C57BL/6

 MP:0010873 decreased trabecular bone mass "reduced total amount of trabecular bone tissue contained in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bgntm1Mfy/Y,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0010962 decreased compact bone mass 
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Allelic Composition: Bgntm1Mfy/Y,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0011346 renal tubule atrophy "acquired diminution of the size of the loops of Henle, the proximal convoluted tubule or the distal convoluted tubule associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:anna]
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Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0011501 increased glomerular capsule space "increased volume of the luminal region between the glomerular capsule visceral and parietal layers, into which filtrate enters after passing through the filtration barrier from the glomerular capillaries" [MGI:csmith]
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Allelic Composition: GnaqMhdadsk1/GnaqMhdadsk1
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0011642 abnormal bone collagen fibril morphology "any structural anomaly of the connective tissue bundles in the extracellular matrix of bone tissue that are composed of collagen, and play a role in tissue strength and elasticity" [MGI:csmith]
Show

Allelic Composition: Bgntm1Mfy/Y,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0012008 delayed parturition "the process of labor and delivery in female animals occurs later in gestation than expected or lack of progress in a labor already initiated" [MGI:csmith]
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Allelic Composition: Bgntm1Mfy/Bgn+,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0012009 early parturition "the process of labor and delivery in female animals occurs earlier in gestation than expected" [MGI:csmith]
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Allelic Composition: Bgntm1Mfy/Bgntm1Mfy,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Bgntm1Mfy/Bgn+,Dcntm1Ioz/Dcntm1Ioz
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000018623 Mmp7 / matrix metallopeptidase 7 / P09237*  / reaction
 ENSMUSG00000016942 Q9DBI0 / Tmprss6 / Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant 2, mRNA. / Q8IU80* / transmembrane serine protease 6*  / reaction
 ENSMUSG00000031740 Mmp2 / P33434 / 72 kDa type IV collagenase PEX / P08253* / matrix metallopeptidase 2*  / reaction
 ENSMUSG00000000957 Mmp14 / P53690 / Matrix metalloproteinase-14 / P50281* / matrix metallopeptidase 14*  / reaction






 

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