ENSMUSG00000019932


Mus musculus

Features
Gene ID: ENSMUSG00000019932
  
Biological name :Kera
  
Synonyms : Kera / Keratocan / O35367
  
Possible biological names infered from orthology : O60938
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C3
Gene start: 97606879
Gene end: 97613692
  
Corresponding Affymetrix probe sets: 10365987 (MoGene1.0st)   1418063_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000100923
NCBI entrez gene - 16545     See in Manteia.
MGI - MGI:1202398
RefSeq - XM_006513273
RefSeq - NM_008438
RefSeq Peptide - NP_032464
swissprot - O35367
swissprot - A4FUJ3
Ensembl - ENSMUSG00000019932
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 keraENSDARG00000056938Danio rerio
 KERAENSGALG00000011270Gallus gallus
 KERAENSG00000139330Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Prelp / Q9JK53 / proline arginine-rich end leucine-rich repeat / P51888* / proline and arginine rich end leucine rich repeat protein*ENSMUSG0000004157752
Omd / O35103 / Osteomodulin / Q99983*ENSMUSG0000004836838
Fmod / P50608 / Fibromodulin / Q06828*ENSMUSG0000004155938
Lum / P51885 / Lumican / P51884*ENSMUSG0000003644636
Ecm2 / Q5FW85 / Extracellular matrix protein 2 / O94769*ENSMUSG0000004363129
Podn / Q7TQ62 / podocan / Q7Z5L7*ENSMUSG0000002860026
Podnl1 / Q6P3Y9 / Podocan-like protein 1 / Q6PEZ8* / podocan like 1*ENSMUSG0000001288926
Aspn / Q99MQ4 / Asporin / Q9BXN1*ENSMUSG0000002138825
Bgn / P28653 / biglycan / P21810*ENSMUSG0000003137525
Dcn / P28654 / Decorin / P07585*ENSMUSG0000001992924


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0061303 cornea development in camera-type eye IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Keratan sulfate biosynthesis
Keratan sulfate degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000222 decreased neutrophil count "fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ptstm1Thny/Ptstm1Thny
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0001845 abnormal inflammatory response "aberrant reaction of the microcirculation characterized by movement of fluid and leukocytes from the blood into extravascular tissues" [Pathology:ISBN 0-397-51047-0]
Show

Allelic Composition: Ptstm1Thny/Ptstm1Thny
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0004221 abnormal iridocorneal angle "any structural abnormality of the acute angle occurring between the iris and the cornea at the periphery of the anterior chamber of the eye" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptstm1Thny/Ptstm1Thny
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0005300 abnormal corneal stroma morphology "structural anomaly of the lamellated connective tissue of the cornea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptstm1Thny/Ptstm1Thny
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0005543 corneal thinning "decreased thickness of the cornea, the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ptstm1Thny/Ptstm1Thny
Genetic Background: involves: 129/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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