ENSMUSG00000041577


Mus musculus

Features
Gene ID: ENSMUSG00000041577
  
Biological name :Prelp
  
Synonyms : Prelp / proline arginine-rich end leucine-rich repeat / Q9JK53
  
Possible biological names infered from orthology : P51888 / proline and arginine rich end leucine rich repeat protein
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: E4
Gene start: 133910304
Gene end: 133921414
  
Corresponding Affymetrix probe sets: 10357870 (MoGene1.0st)   1416321_s_at (Mouse Genome 430 2.0 Array)   1416322_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000048803
NCBI entrez gene - 116847     See in Manteia.
MGI - MGI:2151110
RefSeq - XM_006529085
RefSeq - NM_054077
RefSeq - XM_006529083
RefSeq - XM_006529084
RefSeq Peptide - NP_473418
swissprot - Q543S0
swissprot - Q9JK53
Ensembl - ENSMUSG00000041577
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prelpENSDARG00000070597Danio rerio
 PRELPENSGALG00000034456Gallus gallus
 PRELPENSG00000188783Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kera / O35367 / Keratocan / O60938*ENSMUSG0000001993248
Fmod / P50608 / Fibromodulin / Q06828*ENSMUSG0000004155938
Omd / O35103 / Osteomodulin / Q99983*ENSMUSG0000004836836
Lum / P51885 / Lumican / P51884*ENSMUSG0000003644634
Bgn / P28653 / biglycan / P21810*ENSMUSG0000003137526
Dcn / P28654 / Decorin / P07585*ENSMUSG0000001992926
Ecm2 / Q5FW85 / Extracellular matrix protein 2 / O94769*ENSMUSG0000004363125
Aspn / Q99MQ4 / Asporin / Q9BXN1*ENSMUSG0000002138825
Podn / Q7TQ62 / podocan / Q7Z5L7*ENSMUSG0000002860025
Podnl1 / Q6P3Y9 / Podocan-like protein 1 / Q6PEZ8* / podocan like 1*ENSMUSG0000001288924


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR027216  Prolargin
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007569 cell aging IDA
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0031012 extracellular matrix IEA
 cellular_componentGO:0070062 extracellular exosome IBA
 molecular_functionGO:0005201 extracellular matrix structural constituent IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
Keratan sulfate biosynthesis
Keratan sulfate degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005344 increased circulating bilirubin level "greater than the normal concentration in the blood of this yellow heme breakdown product" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204]
Show

Allelic Composition: Pitx3tm1.1(KOMP)Vlcg/Pitx3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Pitx3tm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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