ENSG00000188783


Homo sapiens

Features
Gene ID: ENSG00000188783
  
Biological name :PRELP
  
Synonyms : P51888 / PRELP / proline and arginine rich end leucine rich repeat protein
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q32.1
Gene start: 203475828
Gene end: 203491352
  
Corresponding Affymetrix probe sets: 204223_at (Human Genome U133 Plus 2.0 Array)   228224_at (Human Genome U133 Plus 2.0 Array)   37022_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000343924
NCBI entrez gene - 5549     See in Manteia.
OMIM - 601914
RefSeq - NM_201348
RefSeq - NM_002725
RefSeq Peptide - NP_002716
RefSeq Peptide - NP_958505
swissprot - P51888
Ensembl - ENSG00000188783
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prelpENSDARG00000070597Danio rerio
 PRELPENSGALG00000034456Gallus gallus
 PrelpENSMUSG00000041577Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KERA / O60938 / keratocanENSG0000013933049
FMOD / Q06828 / fibromodulinENSG0000012217638
OMD / Q99983 / osteomodulinENSG0000012708335
LUM / P51884 / lumicanENSG0000013932935
ECM2 / O94769 / extracellular matrix protein 2ENSG0000010682326
DCN / P07585 / decorinENSG0000001146526
ASPN / Q9BXN1 / asporinENSG0000010681925
BGN / P21810 / biglycanENSG0000018249225
PODN / Q7Z5L7 / podocanENSG0000017434825
PODNL1 / Q6PEZ8 / podocan like 1ENSG0000013200022


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR027216  Prolargin
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development TAS
 biological_processGO:0007569 cell aging IEA
 biological_processGO:0018146 keratan sulfate biosynthetic process TAS
 biological_processGO:0042340 keratan sulfate catabolic process TAS
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0031012 extracellular matrix ISS
 cellular_componentGO:0043202 lysosomal lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1903561 extracellular vesicle HDA
 molecular_functionGO:0005201 extracellular matrix structural constituent TAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
Keratan sulfate biosynthesis
Keratan sulfate degradation
Defective CHST6 causes MCDC1
Defective ST3GAL3 causes MCT12 and EIEE15
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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