ENSG00000174348


Homo sapiens

Features
Gene ID: ENSG00000174348
  
Biological name :PODN
  
Synonyms : PODN / podocan / Q7Z5L7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p32.3
Gene start: 53062052
Gene end: 53085502
  
Corresponding Affymetrix probe sets: 226522_at (Human Genome U133 Plus 2.0 Array)   233148_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000308315
Ensembl peptide - ENSP00000360555
Ensembl peptide - ENSP00000379212
Ensembl peptide - ENSP00000479233
NCBI entrez gene - 127435     See in Manteia.
OMIM - 608661
RefSeq - XM_017000294
RefSeq - NM_001199080
RefSeq - NM_001199081
RefSeq - NM_001199082
RefSeq - NM_153703
RefSeq - XM_005270457
RefSeq - XM_011540677
RefSeq Peptide - NP_714914
RefSeq Peptide - NP_001186009
RefSeq Peptide - NP_001186010
RefSeq Peptide - NP_001186011
swissprot - Q7Z5L7
Ensembl - ENSG00000174348
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 podnENSDARG00000019025Danio rerio
 PODNENSGALG00000021869Gallus gallus
 PodnENSMUSG00000028600Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PODNL1 / Q6PEZ8 / podocan like 1ENSG0000013200038
ECM2 / O94769 / extracellular matrix protein 2ENSG0000010682321
ASPN / Q9BXN1 / asporinENSG0000010681914
DCN / P07585 / decorinENSG0000001146514
LUM / P51884 / lumicanENSG0000013932914
OMD / Q99983 / osteomodulinENSG0000012708314
PRELP / P51888 / proline and arginine rich end leucine rich repeat proteinENSG0000018878314
FMOD / Q06828 / fibromodulinENSG0000012217614
KERA / O60938 / keratocanENSG0000013933013
BGN / P21810 / biglycanENSG0000018249213


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR026906  Leucine rich repeat 5
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0030336 negative regulation of cell migration IDA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031012 extracellular matrix IDA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005518 collagen binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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