ENSGALG00000011377


Gallus gallus

Features
Gene ID: ENSGALG00000011377
  
Biological name :METAP2
  
Synonyms : METAP2 / methionine aminopeptidase 2
  
Possible biological names infered from orthology : methionyl aminopeptidase 2 / O08663 / P50579
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 45535393
Gene end: 45550173
  
Corresponding Affymetrix probe sets: GgaAffx.12872.1.S1_s_at (Chicken Array)   GgaAffx.7229.3.S1_at (Chicken Array)   GgaAffx.7229.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018537
NCBI entrez gene - 417912     See in Manteia.
RefSeq - NM_001006233
RefSeq Peptide - NP_001006233
swissprot - F1P4G0
Ensembl - ENSGALG00000011377
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 metap2aENSDARG00000069261Danio rerio
 metap2bENSDARG00000102571Danio rerio
 METAP2ENSG00000111142Homo sapiens
 Metap2ENSMUSG00000036112Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PA2G4* / P50580* / Q9UQ80* / AC034102.2* / proliferation-associated 2G4* / Proliferation-associated protein 2G4 *ENSGALG0000003421815


Protein motifs (from Interpro)
Interpro ID Name
 IPR000994  Peptidase M24
 IPR001714  Peptidase M24, methionine aminopeptidase
 IPR002468  Peptidase M24A, methionine aminopeptidase, subfamily 2
 IPR011991  ArsR-like helix-turn-helix domain
 IPR018349  Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016485 protein processing IEA
 biological_processGO:0018206 peptidyl-methionine modification IEA
 biological_processGO:0031365 N-terminal protein amino acid modification IEA
 biological_processGO:0070084 protein initiator methionine removal IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0004177 aminopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008235 metalloexopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070006 metalloaminopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Inactivation, recovery and regulation of the phototransduction cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000028697 GNAT1 / G protein subunit alpha transducin 1 / P11488* / P20612* / guanine nucleotide binding protein, alpha transducing 1*  / reaction






 

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