ENSDARG00000069261


Danio rerio

Features
Gene ID: ENSDARG00000069261
  
Biological name :metap2a
  
Synonyms : metap2a / methionyl aminopeptidase 2a
  
Possible biological names infered from orthology : METAP2 / methionine aminopeptidase 2 / methionyl aminopeptidase 2 / O08663 / P50579
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 25950372
Gene end: 26016541
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000109712
NCBI entrez gene - 794589     See in Manteia.
RefSeq - NM_001100054
RefSeq Peptide - NP_001093524
swissprot - A5WVX8
ZFIN ID - ZDB-GENE-061013-5
Ensembl - ENSDARG00000069261
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 METAP2ENSGALG00000011377Gallus gallus
 METAP2ENSG00000111142Homo sapiens
 Metap2ENSMUSG00000036112Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
metap2b / methionyl aminopeptidase 2b / P50579* / METAP2* / O08663* / methionyl aminopeptidase 2* / methionine aminopeptidase 2*ENSDARG0000010257179
pa2g4b / proliferation-associated 2G4, b / PA2G4* / Q9UQ80* / P50580* / AC034102.2* / proliferation-associated 2G4* / Proliferation-associated protein 2G4 *ENSDARG0000007065716
pa2g4a / proliferation-associated 2G4, a / PA2G4* / Q9UQ80* / P50580* / AC034102.2* / proliferation-associated 2G4* / Proliferation-associated protein 2G4 *ENSDARG0000003957815


Protein motifs (from Interpro)
Interpro ID Name
 IPR000994  Peptidase M24
 IPR001714  Peptidase M24, methionine aminopeptidase
 IPR002468  Peptidase M24A, methionine aminopeptidase, subfamily 2
 IPR011991  ArsR-like helix-turn-helix domain
 IPR018349  Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0070084 protein initiator methionine removal IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004177 aminopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008235 metalloexopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070006 metalloaminopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Inactivation, recovery and regulation of the phototransduction cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000044199 gnat1 / guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 / P20612* / P11488* / G protein subunit alpha transducin 1* / guanine nucleotide binding pro...  / reaction






 

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