ENSGALG00000011715


Gallus gallus

Features
Gene ID: ENSGALG00000011715
  
Biological name :HSPA2
  
Synonyms : heat shock 70 kDa protein / HSPA2
  
Possible biological names infered from orthology : heat shock protein family A (Hsp70) member 2 / Heat shock-related 70 kDa protein 2 / P17156 / P54652
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 52952583
Gene end: 52954953
  
Corresponding Affymetrix probe sets: Gga.4942.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019120
NCBI entrez gene - 423504     See in Manteia.
RefSeq - NM_001006685
RefSeq Peptide - NP_001006686
swissprot - Q7SX63
Ensembl - ENSGALG00000011715
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HSPA2ENSG00000126803Homo sapiens
 Hspa2ENSMUSG00000059970Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HSPA8 / heat shock cognate 71 kDa protein / P11142* / P63017* / heat shock protein family A (Hsp70) member 8*ENSGALG0000000651289
HSPA5 / Q90593 / 78 kDa glucose-regulated protein / P11021* / P20029* / heat shock protein 5* / heat shock protein family A (Hsp70) member 5*ENSGALG0000000100064
HSPA5* / P11021* / P20029* / heat shock protein 5* / heat shock protein family A (Hsp70) member 5*ENSGALG0000003349840
HSPA14* / Q0VDF9* / Q99M31* / Heat shock 70 kDa protein 14 * / heat shock protein family A (Hsp70) member 14*ENSGALG0000003520123


Protein motifs (from Interpro)
Interpro ID Name
 IPR013126  Heat shock protein 70 family
 IPR018181  Heat shock protein 70, conserved site
 IPR029047  Heat shock protein 70kD, peptide-binding domain superfamily
 IPR029048  Heat shock protein 70kD, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0007140 male meiotic nuclear division IEA
 biological_processGO:0007141 male meiosis I IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007286 spermatid development IEA
 biological_processGO:0009408 response to heat IDA
 biological_processGO:0009409 response to cold IDA
 biological_processGO:0010243 response to organonitrogen compound IDA
 biological_processGO:0014070 response to organic cyclic compound IDA
 biological_processGO:0031647 regulation of protein stability ISS
 biological_processGO:0032570 response to progesterone IDA
 biological_processGO:0032781 positive regulation of ATPase activity IEA
 biological_processGO:0042026 protein refolding ISS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0046034 ATP metabolic process ISS
 biological_processGO:0070194 synaptonemal complex disassembly IEA
 biological_processGO:0090084 negative regulation of inclusion body assembly IEA
 biological_processGO:1901896 positive regulation of calcium-transporting ATPase activity IEA
 biological_processGO:1902904 negative regulation of supramolecular fiber organization ISS
 cellular_componentGO:0000151 ubiquitin ligase complex ISS
 cellular_componentGO:0000795 synaptonemal complex IEA
 cellular_componentGO:0000974 Prp19 complex ISS
 cellular_componentGO:0001673 male germ cell nucleus IEA
 cellular_componentGO:0005615 extracellular space ISS
 cellular_componentGO:0005623 cell IDA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005925 focal adhesion ISS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane ISS
 cellular_componentGO:0036128 CatSper complex IEA
 cellular_componentGO:0043204 perikaryon IDA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:0070062 extracellular exosome ISS
 cellular_componentGO:0072562 blood microparticle ISS
 cellular_componentGO:0072687 meiotic spindle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0001664 G-protein coupled receptor binding ISS
 molecular_functionGO:0003723 RNA binding ISS
 molecular_functionGO:0005524 ATP binding ISS
 molecular_functionGO:0016887 ATPase activity ISS
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0023026 MHC class II protein complex binding ISS
 molecular_functionGO:0031072 heat shock protein binding ISS
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISS
 molecular_functionGO:0033142 progesterone receptor binding IPI
 molecular_functionGO:0051082 unfolded protein binding IEA
 molecular_functionGO:0051861 glycolipid binding IEA
 molecular_functionGO:0055131 C3HC4-type RING finger domain binding ISS
 molecular_functionGO:0097718 disordered domain specific binding IEA


Pathways (from Reactome)
Pathway description
Regulation of HSF1-mediated heat shock response
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Attenuation phase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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