ENSGALG00000001000


Gallus gallus

Features
Gene ID: ENSGALG00000001000
  
Biological name :HSPA5
  
Synonyms : 78 kDa glucose-regulated protein / HSPA5 / Q90593
  
Possible biological names infered from orthology : heat shock protein 5 / heat shock protein family A (Hsp70) member 5 / P11021 / P20029
  
Species: Gallus gallus
  
Chr. number: 17
Strand: -1
Band:
Gene start: 10076957
Gene end: 10081027
  
Corresponding Affymetrix probe sets: Gga.4219.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001474
NCBI entrez gene - 396487     See in Manteia.
RefSeq - NM_205491
RefSeq Peptide - NP_990822
swissprot - Q90593
Ensembl - ENSGALG00000001000
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hspa5ENSDARG00000103846Danio rerio
 HSPA5ENSG00000044574Homo sapiens
 Hspa5ENSMUSG00000026864Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HSPA8 / heat shock cognate 71 kDa protein / P11142* / P63017* / heat shock protein family A (Hsp70) member 8*ENSGALG0000000651264
HSPA2 / heat shock 70 kDa protein / P17156* / P54652* / Heat shock-related 70 kDa protein 2 * / heat shock protein family A (Hsp70) member 2*ENSGALG0000001171562
HSPA5* / P11021* / P20029* / heat shock protein 5* / heat shock protein family A (Hsp70) member 5*ENSGALG0000003349856
HSPA14* / Q0VDF9* / Q99M31* / Heat shock 70 kDa protein 14 * / heat shock protein family A (Hsp70) member 14*ENSGALG0000003520122


Protein motifs (from Interpro)
Interpro ID Name
 IPR013126  Heat shock protein 70 family
 IPR018181  Heat shock protein 70, conserved site
 IPR029047  Heat shock protein 70kD, peptide-binding domain superfamily
 IPR029048  Heat shock protein 70kD, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0090074 negative regulation of protein homodimerization activity ISS
 biological_processGO:1903895 negative regulation of IRE1-mediated unfolded protein response ISS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003476 ERN1 / endoplasmic reticulum to nucleus signaling 1 / O75460* / Q9EQY0* / Serine/threonine-protein kinase/endoribonuclease IRE1 Serine/threonine-protein kinase Endoribonuclease*  / complex
 ENSGALG00000032278 ATF6 / activating transcription factor 6 / F6VAN0* / P18850* / Cyclic AMP-dependent transcription factor ATF-6 alpha Processed cyclic AMP-dependent transcription factor ATF-6 alpha*  / complex






 

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