ENSGALG00000011966


Gallus gallus

Features
Gene ID: ENSGALG00000011966
  
Biological name :RANGAP1
  
Synonyms : RANGAP1 / ran GTPase-activating protein 1
  
Possible biological names infered from orthology : P46060 / P46061
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 49768544
Gene end: 49787684
  
Corresponding Affymetrix probe sets: GgaAffx.12605.1.S1_at (Chicken Array)   GgaAffx.12605.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019492
NCBI entrez gene - 417997     See in Manteia.
RefSeq - NM_001006237
RefSeq - XM_015285127
RefSeq - XM_015285130
RefSeq Peptide - NP_001006237
swissprot - F1NIE8
Ensembl - ENSGALG00000011966
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rangap1aENSDARG00000041317Danio rerio
 rangap1bENSDARG00000056059Danio rerio
 P46060ENSG00000100401Homo sapiens
 P46061ENSMUSG00000022391Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR009109  Ran-GTPase activating protein 1, C-terminal
 IPR027038  Ran GTPase-activating protein
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0046826 negative regulation of protein export from nucleus IEA
 biological_processGO:0090630 activation of GTPase activity IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016235 aggresome IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0008536 Ran GTPase binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA replication proteins
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008435 SUMO1 / Q8QGH2 / Small ubiquitin-related modifier 1 / P63166* / P63165* / small ubiquitin-like modifier 1*  / complex
 ENSGALG00000006428 UBE2I / P63283 / SUMO-conjugating enzyme UBC9 / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / complex






 

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