ENSGALG00000012123


Gallus gallus

Features
Gene ID: ENSGALG00000012123
  
Biological name :PAX6
  
Synonyms : paired box 6 / PAX6
  
Possible biological names infered from orthology : P26367 / P63015 / Paired box protein Pax-6
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 5201971
Gene end: 5218801
  
Corresponding Affymetrix probe sets: Gga.556.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019777
Ensembl peptide - ENSGALP00000019778
Ensembl peptide - ENSGALP00000049020
NCBI entrez gene - 395943     See in Manteia.
RefSeq - XM_015286144
RefSeq - NM_205066
RefSeq - XM_015286141
RefSeq - XM_015286142
RefSeq - XM_015286143
RefSeq - XM_015286136
RefSeq - XM_015286137
RefSeq - XM_015286138
RefSeq - XM_015286139
RefSeq - XM_015286140
RefSeq Peptide - NP_990397
swissprot - O42348
swissprot - F1NF66
Ensembl - ENSGALG00000012123
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PAX6ENSG00000007372Homo sapiens
 Pax6ENSMUSG00000027168Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PAX7 / paired box 7 / P23759* / P47239* / Paired box protein Pax-7 *ENSGALG0000004320435
PAX2 / paired box 2 / Q02962*ENSGALG0000000568930
PAX5 / paired box 5 / Q02548* / Q02650* / Paired box protein Pax-5 *ENSGALG0000001643130
PAX1 / paired box 1 / P09084* / P15863* / Paired box protein Pax-1 *ENSGALG0000003904024
PAX9 / paired box protein Pax-9 / P47242* / P55771* / paired box 9*ENSGALG0000001011423
PAX3 / paired box protein Pax-3 / P23760* / P24610* / paired box 3*ENSGALG0000003094419


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001523  Paired domain
 IPR009057  Homeobox-like domain superfamily
 IPR011991  ArsR-like helix-turn-helix domain
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000132 establishment of mitotic spindle orientation IEA
 biological_processGO:0001568 blood vessel development IEA
 biological_processGO:0001709 cell fate determination IEA
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0002052 positive regulation of neuroblast proliferation IEA
 biological_processGO:0002088 lens development in camera-type eye IEA
 biological_processGO:0003002 regionalization IEA
 biological_processGO:0003309 type B pancreatic cell differentiation IEA
 biological_processGO:0003322 pancreatic A cell development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007224 smoothened signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007435 salivary gland morphogenesis IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0009786 regulation of asymmetric cell division IEA
 biological_processGO:0009950 dorsal/ventral axis specification IEA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0021543 pallium development IEA
 biological_processGO:0021778 oligodendrocyte cell fate specification IEA
 biological_processGO:0021796 cerebral cortex regionalization IEA
 biological_processGO:0021798 forebrain dorsal/ventral pattern formation IEA
 biological_processGO:0021902 commitment of neuronal cell to specific neuron type in forebrain IEA
 biological_processGO:0021905 forebrain-midbrain boundary formation IEA
 biological_processGO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification IEA
 biological_processGO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification IEA
 biological_processGO:0021918 regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment IEA
 biological_processGO:0021978 telencephalon regionalization IEA
 biological_processGO:0021983 pituitary gland development IEA
 biological_processGO:0021986 habenula development IEA
 biological_processGO:0023019 signal transduction involved in regulation of gene expression IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030216 keratinocyte differentiation IEA
 biological_processGO:0030334 regulation of cell migration IEA
 biological_processGO:0030858 positive regulation of epithelial cell differentiation IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0032808 lacrimal gland development IEA
 biological_processGO:0033365 protein localization to organelle IEA
 biological_processGO:0042462 eye photoreceptor cell development IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0045165 cell fate commitment IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048505 regulation of timing of cell differentiation IEA
 biological_processGO:0048596 embryonic camera-type eye morphogenesis IEA
 biological_processGO:0048708 astrocyte differentiation IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 biological_processGO:0050767 regulation of neurogenesis IEA
 biological_processGO:0060041 retina development in camera-type eye IEA
 biological_processGO:0061072 iris morphogenesis IEA
 biological_processGO:0061303 cornea development in camera-type eye IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 biological_processGO:2000178 negative regulation of neural precursor cell proliferation IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0035035 histone acetyltransferase binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0070410 co-SMAD binding IEA
 molecular_functionGO:0070412 R-SMAD binding IEA
 molecular_functionGO:0071837 HMG box domain binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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