Manteia

ID	Phenotype	Definition	Genetic BG
MP:0000018	small ears	"outer ears of a smaller than normal size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Pax6^Sey-H/Pax6⁺ Genetic Background: involves: 101/H * C3H/HeH
MP:0000024	lowered ear position	"outer ears which are situated below the normal location " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Pax6^Sey-H/Pax6⁺ Genetic Background: involves: 101/H * C3H/HeH
MP:0000102	abnormal nasal bone morphology	"malformed elongated rectangular bone that forms part of the nasal bridge" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17489]	Show Allelic Composition: Chek1^tm1Sje/Chek1^tm1Sje,Trp53^tm1Brd/Trp53^tm1Brd Genetic Background: involves: 129S7/SvEvBrd
MP:0000352	decreased cell proliferation	"less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Nlgn2^tm1.1Sud/Nlgn2^tm1.1Sud Genetic Background: involves: C57BL/6NTac
MP:0000373	belly spot	"the appearance of a round area of white fur on the belly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey Allelic Composition: Pax6^Sey-H/Pax6⁺ Genetic Background: involves: 101/H * C3H/HeH
MP:0000428	abnormal craniofacial morphology	"anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pax6^4Neu/Pax6^4Neu Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^7Neu/Pax6^7Neu Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^6Neu/Pax6^6Neu Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^2Neu/Pax6^2Neu Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^5Neu/Pax6^5Neu Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^8Neu/Pax6^8Neu Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^9Neu/Pax6^9Neu Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^10Neu/Pax6^10Neu Genetic Background: involves: 102 * C3H
MP:0000445	short snout	"reduced length of the anterior facial part of the muzzle" [J:53370]	Show Allelic Composition: Pycard^tm1Nnz/Pycard^tm1Nnz Genetic Background: involves: 129 * C57BL/6
MP:0000450	absent snout	"missing anterior facial part of the muzzle" [J:35802]	Show Allelic Composition: Fas^lpr/Fas^lpr,Ighm^tm1Cgn/Ighm^tm1Cgn Genetic Background: involves: 129S2/SvPas * C57BL/6 * MRL/Mp
MP:0000783	abnormal forebrain morphology	"malformed or absent anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: involves: 102 * C3H
MP:0000785	telencephalon hypoplasia	"reduced cell number in cerebral cortex and basal ganglia" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]	Show Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: involves: 102 * C3H
MP:0000787	abnormal telencephalon morphology	"any malformation or absence of the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Mitf^mi-bw/Mitf^mi-bw Genetic Background: C3H Allelic Composition: Emx2^tm1Sia/Emx2^tm1Sia,Pax6^Sey/Pax6^Sey Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Pax6^tm1.1Ued/Pax6^tm1.1Ued Genetic Background: involves: 129P2/OlaHsd * FVB/N * ICR
MP:0000788	abnormal cerebral cortex morphology	"malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]	Show Allelic Composition: Emx2^tm1Sia/Emx2^tm1Sia,Pax6^Sey/Pax6^Sey Genetic Background: involves: C57BL/6 * CBA
MP:0000809	absent hippocampus	"missing convoluted brain structure below the cerebral hemispheres; forms part of the limbic system" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:59284]	Show Allelic Composition: Emx2^tm1Sia/Emx2^tm1Sia,Pax6^Sey/Pax6^Sey Genetic Background: involves: C57BL/6 * CBA
MP:0000815	abnormal ammon gyrus morphology	"malformations of one of the two interlocking gyri of the hippocampus; a circonvolution of rhinencephalon, the grey substance of which is rich in big pyramidal neuronal cells " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Emx2^tm1Sia/Emx2^tm1Sia,Pax6^Sey/Pax6^Sey Genetic Background: involves: C57BL/6 * CBA
MP:0000830	abnormal diencephalon morphology	"any malformation or absence of the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show
MP:0000832	abnormal thalamus morphology	"malformation or absence of the large ovoid mass of paired bodies containing mostly gray matter and forming part of the lateral wall of the third ventricle of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Emx2^tm1Sia/Emx2^tm1Sia,Pax6^Sey/Pax6^Sey Genetic Background: involves: C57BL/6 * CBA
MP:0000849	abnormal cerebellum morphology	"any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Foxc2^tm1Miu/Foxc2^tm1Miu Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: involves: ICR
MP:0000864	abnormal vermis	"malformation in the narrow middle zone between the two hemispheres of the cerebellum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61509]	Show Allelic Composition: Foxc2^tm1Miu/Foxc2^tm1Miu Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: involves: ICR
MP:0000872	abnormal external granule cell layer	"malformation of the transient layer of the cerebellar cortex which is composed of the dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator]	Show Allelic Composition: Foxc2^tm1Miu/Foxc2^tm1Miu Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: involves: ICR
MP:0000885	ectopic Purkinje cell	"Purkinje cell body resides in places other than the Purkinje cell layer in the cerebellum" [MGI:tc, J:60896]	Show Allelic Composition: Foxc2^tm1Miu/Foxc2^tm1Miu Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: involves: ICR
MP:0000913	abnormal brain development	"malformed or incomplete differentiation of the brain" [MGI:cls, J:49840]	Show Allelic Composition: Il2rg^tm1Cgn/Y Genetic Background: involves: 129 * CB20
MP:0000914	exencephaly	"neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: Pax6^Coop/Pax6⁺ Genetic Background: C3.D2-Pax6^Coop Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey
MP:0000934	abnormal telencephalon development	"malformed or incomplete differentiation of the anterior division of the embryonic prosencephalon " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:49840]	Show Allelic Composition: Il2rg^tm1Cgn/Y Genetic Background: involves: 129 * CB20 Allelic Composition: Pax6^Mhdaaey18/Pax6^Mhdaaey18 Genetic Background: involves: C3HeB/FeJ Allelic Composition: Pax6^tm1Ued/Pax6^tm1Ued,Tg(Six3-cre)69Frty/0 Genetic Background: involves: 129P2/OlaHsd * ICR Allelic Composition: Pax6^{tm2(Pax6_i5a,Pax2)Xzh}/Pax6^{tm2(Pax6_i5a,Pax2)Xzh} Genetic Background: involves: 129S6/SvEvTac Allelic Composition: Pax6^{tm2.1(Pax6_i5a,Pax2)Xzh}/Pax6^{tm2.1(Pax6_i5a,Pax2)Xzh} Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
MP:0001258	decreased body length	"decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]	Show Allelic Composition: Nr1h2^tm1Djm/Nr1h2^tm1Djm,Nr1h3^tm1Djm/Nr1h3^tm1Djm Genetic Background: involves: 129S6/SvEvTac * C57BL/6
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey Allelic Composition: Pax6^Sey-H/Pax6⁺ Genetic Background: involves: 101/H * C3H/HeH
MP:0001286	abnormal eye development	"malformation or arrest of differentiation of the visual organ" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:49840]	Show Allelic Composition: Pax6^Sey/Pax6⁺ Genetic Background: involves: C57BL/6 Allelic Composition: Pax6^{tm2(Pax6_i5a,Pax2)Xzh}/Pax6^{tm2(Pax6_i5a,Pax2)Xzh} Genetic Background: involves: 129S6/SvEvTac Allelic Composition: Pax6^{tm2.1(Pax6_i5a,Pax2)Xzh}/Pax6^{tm2.1(Pax6_i5a,Pax2)Xzh} Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
MP:0001288	abnormal lens induction	"malformation of or failure to form the transparent, biconvex structure of the eye which is situated behind the iris and in front of the vitreous humor" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Foxc2^tm1Miu/Foxc2^tm1Miu Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001292	abnormal lens vesicle development	"malformation or abnormal patterning of the lens vesicle of the eye" [J:49424]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^Sey-Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^132-14Neu/Pax6⁺ Genetic Background: involves: 101 * C3H Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: involves: Swiss Allelic Composition: Pax6^132-14Neu/Pax6⁺ Genetic Background: C3.Cg-Pax6^132-14Neu Allelic Composition: Pax6^Sey/Pax6⁺ Genetic Background: C.Cg-Pax6^Sey Allelic Composition: Pax6^tm1Lan/Pax6^tm1Lan Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm1Lan/Pax6⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0001293	anophthalmia	"congenital absence of all tissues of the eyes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CML, J:71979]	Show Allelic Composition: Pax6^4Neu/Pax6^4Neu Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^3Neu/Pax6^3Neu Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^Coop/Pax6^Coop Genetic Background: C3.D2-Pax6^Coop Allelic Composition: Pax6^tm1Pgr/Pax6^tm1Pgr Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI Allelic Composition: Pax6^132-14Neu/Pax6^132-14Neu Genetic Background: involves: 101 * C3H Allelic Composition: Pax6^1Jrt/Pax6⁺ Genetic Background: C3.B6-Pax6^1Jrt Allelic Composition: Pax6^7Neu/Pax6^7Neu Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^6Neu/Pax6^6Neu Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^2Neu/Pax6^2Neu Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^5Neu/Pax6^5Neu Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^8Neu/Pax6^8Neu Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^9Neu/Pax6^9Neu Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^10Neu/Pax6^10Neu Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^Sey/Pax6^Sey-H Genetic Background: involves: 101/H * C3H/HeH * C57BL/10 Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: involves: C57BL/6 Allelic Composition: Pax6^Aey80/Pax6^Aey80 Genetic Background: C3HeB/FeJ-Pax6^Aey80
MP:0001297	microphthalmia	"reduced average size of the eyes" [J:18048]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^Coop/Pax6⁺ Genetic Background: C3.D2-Pax6^Coop Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey Allelic Composition: Pax6^Sey-H/Pax6⁺ Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: Pax6^Sey-Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^1Jrt/Pax6⁺ Genetic Background: C3.B6-Pax6^1Jrt Allelic Composition: Pax6^Leca1/Pax6^Leca1 Genetic Background: involves: BALB/cAnN * C3H/HeN Allelic Composition: Pax6^Leca2/Pax6^Leca2 Genetic Background: involves: BALB/cAnN * C3H/HeN Allelic Composition: Pax6^Leca3/Pax6^Leca3 Genetic Background: involves: BALB/cAnN * C3H/HeN Allelic Composition: Pax6^Leca4/Pax6^Leca4 Genetic Background: involves: BALB/cAnN * C3H/HeN Allelic Composition: Pax6^Mhdaaey18/Pax6⁺ Genetic Background: involves: C3HeB/FeJ Allelic Composition: Pax6^6Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^4Neu/Pax6⁺ Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^ADD4802/Pax6⁺ Genetic Background: involves: C3H * T STOCK Allelic Composition: Pax6^Mhdaaey18/Pax6⁺ Genetic Background: C3HeB/FeJ-Pax6^Mhdaaey18 Allelic Composition: Pax6^Mhdaaey11/Pax6^Mhdaaey11 Genetic Background: C3HeB/FeJ-Pax6^Mhdaaey11 Allelic Composition: Pax6^7Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^2Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^5Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^8Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^9Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^10Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^132-14Neu/Pax6^132-14Neu Genetic Background: C3.Cg-Pax6^132-14Neu Allelic Composition: Pax6^Sey/Pax6⁺ Genetic Background: involves: C57BL/6 Allelic Composition: Pax6^Rgsc20/Pax6⁺ Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl Allelic Composition: Pax6^Rgsc123/Pax6⁺ Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl Allelic Composition: Pax6^Rgsc242/Pax6⁺ Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Sox2^tm1.1Lan/Sox2^tm1.1Lan,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^tm1.2Xzh/Pax6^tm1.2Xzh Genetic Background: B6.129S6-Pax6^tm1.2Xzh Allelic Composition: Pax6^Aey80/Pax6⁺ Genetic Background: C3HeB/FeJ-Pax6^Aey80 Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Rax-cre)1Zkoz/0 Genetic Background: Not Specified
MP:0001303	abnormal lens morphology	"malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^tm1Gfs/Pax6^tm1Gfs Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Pax6^1Jrt/Pax6⁺ Genetic Background: C3.B6-Pax6^1Jrt Allelic Composition: Pax6^132-14Neu/Pax6⁺ Genetic Background: C3.Cg-Pax6^132-14Neu Allelic Composition: Pax6^132-14Neu/Pax6^132-14Neu Genetic Background: C3.Cg-Pax6^132-14Neu Allelic Composition: Pax6^tm1Lan/Pax6^tm1Lan Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^Sey-Neu/Pax6⁺ Genetic Background: involves: 102 * C3H * C3H/HeN Allelic Composition: Pax6^Sey-Neu/Pax6⁺,Sox2^tm1.1Vep/Sox2⁺ Genetic Background: involves: 102 * C3H * C3H/HeN Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N Allelic Composition: Pax6^tm1.2Xzh/Pax6^tm1.2Xzh Genetic Background: B6.129S6-Pax6^tm1.2Xzh Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Rax-cre)1Zkoz/0 Genetic Background: Not Specified
MP:0001304	cataracts	"complete or partial opacity of the lens" [J:65031]	Show Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey Allelic Composition: Pax6^132-14Neu/Pax6⁺ Genetic Background: involves: 101 * C3H Allelic Composition: Pax6^Mhdaaey18/Pax6⁺ Genetic Background: involves: C3HeB/FeJ Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^4Neu/Pax6⁺ Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^ADD4802/Pax6⁺ Genetic Background: involves: C3H * T STOCK Allelic Composition: Pax6^Mhdaaey18/Pax6⁺ Genetic Background: C3HeB/FeJ-Pax6^Mhdaaey18 Allelic Composition: Pax6^Mhdaaey11/Pax6^Mhdaaey11 Genetic Background: C3HeB/FeJ-Pax6^Mhdaaey11 Allelic Composition: Pax6^7Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^Rgsc20/Pax6⁺ Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl Allelic Composition: Pax6^Rgsc123/Pax6⁺ Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl Allelic Composition: Pax6^Rgsc242/Pax6⁺ Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0001306	small lens	"reduced size of the transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey Allelic Composition: Pax6^Sey/Pax6⁺ Genetic Background: B10.Cg-Pax6^Sey Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB Allelic Composition: Pax6^Aey80/Pax6⁺ Genetic Background: C3HeB/FeJ-Pax6^Aey80
MP:0001307	fused cornea/lens	"condition in which the transparent anterior portion of the fibrous coat of the eye is joined to the transparent biconvex cellular refractive structure lying between the iris and vitreous humor of the eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey Allelic Composition: Pax6^132-14Neu/Pax6⁺ Genetic Background: involves: 101 * C3H Allelic Composition: Pax6^tm1Pgr/Pax6⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^Leca1/Pax6^Leca1 Genetic Background: involves: BALB/cAnN * C3H/HeN Allelic Composition: Pax6^Leca2/Pax6^Leca2 Genetic Background: involves: BALB/cAnN * C3H/HeN Allelic Composition: Pax6^Leca3/Pax6^Leca3 Genetic Background: involves: BALB/cAnN * C3H/HeN Allelic Composition: Pax6^Leca4/Pax6^Leca4 Genetic Background: involves: BALB/cAnN * C3H/HeN Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^ADD4802/Pax6⁺ Genetic Background: involves: C3H * T STOCK Allelic Composition: Pax6^132-14Neu/Pax6⁺ Genetic Background: C3.Cg-Pax6^132-14Neu Allelic Composition: Pax6^132-14Neu/Pax6^132-14Neu Genetic Background: C3.Cg-Pax6^132-14Neu Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: involves: 102 * C3H
MP:0001312	abnormal cornea morphology	"malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Pax6^Sey-H/Pax6⁺ Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: Pax6^132-14Neu/Pax6⁺ Genetic Background: C3.Cg-Pax6^132-14Neu Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: C.Cg-Pax6^Sey Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0001314	corneal opacity	"complete or partial clouding of the cornea" [jte:Janan T. Eppig , Mouse Genome Informatics, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Pax6^Coop/Pax6^Coop Genetic Background: C3.D2-Pax6^Coop Allelic Composition: Pax6^1Jrt/Pax6⁺ Genetic Background: C3.B6-Pax6^1Jrt Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^ADD4802/Pax6⁺ Genetic Background: involves: C3H * T STOCK Allelic Composition: Pax6^Mhdaaey18/Pax6⁺ Genetic Background: C3HeB/FeJ-Pax6^Mhdaaey18 Allelic Composition: Pax6^Mhdaaey11/Pax6^Mhdaaey11 Genetic Background: C3HeB/FeJ-Pax6^Mhdaaey11 Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: involves: 102 * C3H
MP:0001317	abnormal pupil morphology	"structural anomaly of the central circular aperture of the iris through which light rays enter the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Pax6^tm1Gfs/Pax6^tm1Gfs Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Pax6^6Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^2Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^5Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^8Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^9Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^10Neu/Pax6⁺ Genetic Background: involves: 102 * C3H
MP:0001319	irregularly shaped pupil	"shape defects in the aperture of the iris through which light rays enter the eye, usually circular " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^4Neu/Pax6⁺ Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^7Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0001322	abnormal iris morphology	"structural anomaly of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Pax6^Coop/Pax6^Coop Genetic Background: C3.D2-Pax6^Coop Allelic Composition: Pax6^tm1Gfs/Pax6^tm1Gfs Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Pax6^tm1Gfs/Pax6⁺ Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Pax6^1Jrt/Pax6⁺ Genetic Background: C3.B6-Pax6^1Jrt Allelic Composition: Pax6^4Neu/Pax6⁺ Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^7Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(CAG-EGFP,-Pax6,-lacZ)1Stoy/0,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(CAG-EGFP,-Pax65a,-lacZ)1Stoy/0,Tg(Dct-cre)1Apdn/0 Genetic Background:* involves: 129S1/Sv * 129X1/SvJ
MP:0001325	abnormal retina morphology	"structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey Allelic Composition: Pax6^tm1Gfs/Pax6^tm1Gfs Genetic Background: involves: 129S7/SvEvBrd
MP:0001330	abnormal optic nerve morphology	"malformation, misprojection or atrophy in the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
MP:0001346	abnormal lacrimal gland morphology	"malformation of the glands that secrete tears" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]	Show Allelic Composition: Cxcr4^tm1Qma/Cxcr4^tm1Qma Genetic Background: involves: 129X1/SvJ * C57BL/6
MP:0001559	hyperglycemia	"abnormally high concentration of glucose in the blood; generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Htr1a^tm1Rhn/Htr1a^tm1Rhn Genetic Background: involves: 129S1/Sv Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: FVB * NMRI
MP:0001698	reduced embryo size	"smaller proportions of embryo compared to littermates" [J:61790]	Show Allelic Composition: Pax6^Sey/Pax6^Sey-H Genetic Background: involves: 101/H * C3H/HeH * C57BL/10
MP:0001732	postnatal growth retardation	"slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Htr1a^tm1Rhn/Htr1a^tm1Rhn Genetic Background: involves: 129S1/Sv Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: FVB * NMRI
MP:0001923	reduced female fertility	"reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: Pax6^Sey-H/Pax6⁺ Genetic Background: involves: 101/H * C3H/HeH
MP:0001944	abnormal pancreas morphology	"malformation of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [il:Ira Lu , Mouse Genome Informatics Curator]	Show Allelic Composition: Il6st^tm1Ern/Il6st⁺,Smad3^tm1Par/Smad3⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0001953	respiratory failure	"cessation of or failure to commence breathing" [MGI:cls, J:60159]	Show
MP:0002001	blindness	"loss of the sense of sight" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pax6^Aey80/Pax6⁺ Genetic Background: C3HeB/FeJ-Pax6^Aey80
MP:0002020	increased tumor incidence	"greater than average number of tumors, usually a specific type" [MGI:cls, J:34193]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
MP:0002083	premature death	"death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
MP:0002092	abnormal eye morphology	"abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pax2^Opdc/Pax2⁺ Genetic Background: involves: BALB/cAnN * C3H/HeN Allelic Composition: Pax6^Leca2/Pax6^Leca2 Genetic Background: involves: BALB/cAnN * C3H/HeN Allelic Composition: Pax6^Leca3/Pax6^Leca3 Genetic Background: involves: BALB/cAnN * C3H/HeN Allelic Composition: Pax6^Leca4/Pax6^Leca4 Genetic Background: involves: BALB/cAnN * C3H/HeN Allelic Composition: Pax6^tm1.1Ued/Pax6^tm1.1Ued Genetic Background: involves: 129P2/OlaHsd * FVB/N * ICR Allelic Composition: Pax6^Aey80/Pax6⁺ Genetic Background: C3HeB/FeJ-Pax6^Aey80
MP:0002116	abnormal craniofacial bone morphology	"abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Efemp1^tm1Lmar/Efemp1⁺ Genetic Background: involves: 129X1/SvJ * BALB/c Allelic Composition: Pax6^Sey/Pax6^Sey-Neu,Tg(Hbb-b1)83Clo/0 Genetic Background: involves: 102 * C3H * C57BL * CBA/Ca * CD-1 * SJL Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: CBACa.Cg-Pax6^Sey Allelic Composition: Pax6^Sey-Neu/Pax6^Sey-Neu Genetic Background: CBACa.Cg-Pax6^Sey-Neu
MP:0002152	abnormal brain morphology	"anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]	Show Allelic Composition: Emx2^tm1Sia/Emx2^tm1Sia,Otx1^tm1Sia/Otx1^tm1Sia Genetic Background: involves: C57BL/6 * CBA
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mir96^Dmdo/Mir96⁺ Genetic Background: C3HeB/FeJ-Mir96^Dmdo
MP:0002199	abnormal brain commissure morphology	"absent or defective structure in a bundle of nerve fibers connecting the two brain hemispheres" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Emx2^tm1Sia/Emx2^tm1Sia,Pax6^Sey/Pax6^Sey Genetic Background: involves: C57BL/6 * CBA
MP:0002206	abnormal CNS synaptic transmission	"defect in the communication from a neuron to a target across a synapse in the central nervous system" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Ercc2^{tm2(ERCC2)Jhjh}/Ercc2^{tm2(ERCC2)Jhjh},Xpa^tm1Hvs/Xpa^tm1Hvs Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0002233	abnormal nose morphology	"any structural anomaly of the organ that is specialized for smell and is part of the respiratory system " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show
MP:0002237	abnormal nasal cavity morphology	"any structural anomaly of the portion of the respiratory tract that extends from the nares to the pharynx; the nasal cavity is lined with ciliated mucosa" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pycard^tm1Nnz/Pycard^tm1Nnz Genetic Background: involves: 129 * C57BL/6
MP:0002404	intestinal adenoma	"benign tumors of the small and large intestine" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
MP:0002546	mydriasis	"dilation of one or both pupils" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pax6^tm1Gfs/Pax6^tm1Gfs Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Pax6^tm1Gfs/Pax6⁺ Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0002575	increased circulating ketone body level	"greater than the normal amount of acetoacetate, 3-hydroxybutyrate and acteone in the blood; produced by fatty acid and carbohydrate metabolism and seen in conditions such as starvation and diabetes mellitus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator, J:71968]	Show Allelic Composition: Htr1a^tm1Rhn/Htr1a^tm1Rhn Genetic Background: involves: 129S1/Sv Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: FVB * NMRI
MP:0002697	abnormal eye size	"anomalous bulk of the organ of vision" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Pax6^Aey80/Pax6⁺ Genetic Background: C3HeB/FeJ-Pax6^Aey80
MP:0002699	abnormal vitreous body	"anomalies of the transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pax6^132-14Neu/Pax6^132-14Neu Genetic Background: C3.Cg-Pax6^132-14Neu Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0002700	opacity of vitreous body	"milky or cloudy eyeball that is impervious to light" [J:30249]	Show Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0002727	decreased circulating insulin level	"less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]	Show Allelic Composition: Htr1a^tm1Rhn/Htr1a^tm1Rhn Genetic Background: involves: 129S1/Sv Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: FVB * NMRI
MP:0002840	abnormal lens fibers morphology	"structural anomaly of the elongated cells of the crystalline lens of the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^tm1Lan/Pax6^tm1Lan Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N Allelic Composition: Pax6^tm1.2Xzh/Pax6^tm1.2Xzh Genetic Background: B6.129S6-Pax6^tm1.2Xzh
MP:0002938	white spotting	"the appearance of patches of white fur" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pax6^Coop/Pax6⁺ Genetic Background: C3.D2-Pax6^Coop Allelic Composition: Pax6^Sey-3H/Pax6⁺ Genetic Background: Not Specified
MP:0002984	retina hypoplasia	"less than normal number of cells in the thin layer of neural tissue lining the back of the eyeball which contains visual receptors" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:80994]	Show Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Rax-cre)1Zkoz/0 Genetic Background: Not Specified
MP:0003077	abnormal cell cycle	"failure to progress or abnormal progression through the stages of of the cell cycle" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91266]	Show Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Rax-cre)1Zkoz/0 Genetic Background: Not Specified
MP:0003078	aphakia	"absence of the crystalline lens of the eye" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Chek1^tm1Sje/Chek1^tm1Sje,Trp53^tm1Brd/Trp53^tm1Brd Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Pax6^tm1.1Zkoz/Pax6^Sey-Neu,Tg(Rax-cre)1Zkoz/0 Genetic Background: involves: 102/El * C3H/Rl
MP:0003093	abnormal anterior stroma morphology	"structural anomaly of the anterior segment of the lamellated connective tissue layer of the cornea" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, J:81616, MeSH:National Library of Medicine - Medical Subject Headings, 2003]	Show Allelic Composition: Pax6^Sey-Neu/Pax6⁺ Genetic Background: involves: 102 * C3H
MP:0003115	abnormal respiratory system development	"aberrant differentiation of pulmonary tissues" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: involves: Swiss
MP:0003232	abnormal forebrain development	"anomaly in the formation or patterning of the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [J:93081, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Il2rg^tm1Cgn/Y Genetic Background: involves: 129 * CB20 Allelic Composition: Pax6^Mhdaaey18/Pax6^Mhdaaey18 Genetic Background: involves: C3HeB/FeJ
MP:0003237	abnormal lens epithelium morphology	"malformation in the one or more of the layers of epithelial cells in the lens" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93301]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^tm1Gfs/Pax6^tm1Gfs Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Pax6^tm1Lan/Pax6^tm1Lan Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Sox2^tm1.1Lan/Sox2^tm1.1Lan,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0003339	decreased number of pancreatic beta cells	"fewer than normal number of the cells of the pancreas that secrete insulin" [ncbi:Matthew Mailman, NCBI request, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Htr1a^tm1Rhn/Htr1a^tm1Rhn Genetic Background: involves: 129S1/Sv Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: FVB * NMRI Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Pdx1-cre)6Cvw/0 Genetic Background: involves: FVB * NMRI
MP:0003425	abnormal optic vesicle formation	"anomalous formation of the hollow outgrowth from the lateral aspects of the embryonic forebrain from which the retina and optic nerve develop" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94391]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: involves: Swiss Allelic Composition: Pax6^tm1Pgr/Pax6^tm2Pgr,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB * NMRI
MP:0003451	absent olfactory bulb	"absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Pax6^tm1Pgr/Pax6^tm1Pgr Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: B10.Cg-Pax6^Sey
MP:0003635	abnormal synaptic transmission	"defect in the communication from a neuron to a target across a synapse " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show
MP:0003687	abnormal intraocular muscle morphology	"malformation of the smooth muscles within the eye" [smb:Susan M Bello, Mouse Genome Informatics Curator, ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0003727	abnormal retinal layer morphology	"malformation in any of the layers that make up the retina" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Rax-cre)1Zkoz/0 Genetic Background: Not Specified
MP:0003728	abnormal photoreceptor layer	"malformation/anomalous structure of the photoreceptor layer" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0003743	abnormal facial morphology	"anomalous structure or development of the face" [ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Pax6^tm1.1Ued/Pax6^tm1.1Ued Genetic Background: involves: 129P2/OlaHsd * FVB/N * ICR
MP:0003793	abnormal submandibular gland morphology	"any structural malformation of either of the large major salivary glands situated beneath the mandible" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0003935	abnormal craniofacial development	"anomaly in the process of forming the face and/or cranium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pax6^4Neu/Pax6^4Neu Genetic Background: either: (involves: 102 * C3H) or (involves: C3H)
MP:0003953	abnormal hormone level	"aberrant tissue or circulating concentration of any substance, usually a peptide or steroid, that has a specific metabolic regulatory effect on the activity or behavior of cells expressing a receptor for the hormone" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Kit^tm1Alf/Kit⁺ Genetic Background: involves: 129S2/SvPas Allelic Composition: Pax6^m1Lsli/Pax6⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0004045	abnormal cell cycle checkpoint function	"anomaly in the amount of time spent at the points in the cell cycle (end of G1 phase, end of G2 phase, and during metaphase) which prevent the cell from progressing to the next phase when conditions are unfavorable" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Rax-cre)1Zkoz/0 Genetic Background: Not Specified
MP:0004046	abnormal mitosis	"anomaly in the process of cell division including both division of the nucleus (karyokinesis) and the cytoplasm (cytokinesis) " [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Rax-cre)1Zkoz/0 Genetic Background: Not Specified
MP:0004098	abnormal granule neuron	"any structural anomaly of the small neurons of the granule cell layer that send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Foxc2^tm1Miu/Foxc2^tm1Miu Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: involves: ICR
MP:0004100	abnormal spinal cord interneuron morphology	"malformation or absence of neurons that exclusively interact with other neurons in the spinal cord" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pax6^tm1Pgr/Pax6^tm1Pgr Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0004171	abnormal pallium development	"anomaly in the progression of the formation of the roof region of the telencephalon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Kit^tm1Alf/Kit⁺ Genetic Background: involves: 129S2/SvPas
MP:0004200	reduced fetal size	"smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey
MP:0004221	abnormal iridocorneal angle	"any structural abnormality of the acute angle occurring between the iris and the cornea at the periphery of the anterior chamber of the eye" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^tm1Pgr/Pax6⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: C.Cg-Pax6^Sey Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
MP:0004224	absent trabecular meshwork	"absence of the pore-like structure surrounding the entire circumference of the anterior chamber through which aqueous humor circulates" [MESH:A09.371.060.932, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
MP:0004226	absent Schlemm s canal	"absence of the vascular structure encircling the anterior chamber of the eye, through which the aqueous humor is returned to the blood circulation" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
MP:0004269	abnormal optic cup morphology	"any structural anomaly of double walled stuctured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^tm1Pgr/Pax6^tm2Pgr,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB * NMRI Allelic Composition: Pax6^Sey/Pax6⁺ Genetic Background: involves: C57BL/6 Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Rax-cre)1Zkoz/0 Genetic Background: Not Specified Allelic Composition: Pax6^tm1.1Zkoz/Pax6^Sey-Neu,Tg(Rax-cre)1Zkoz/0 Genetic Background: involves: 102/El * C3H/Rl Allelic Composition: Pax6^Sey-Neu/Pax6^tm1.1Zkoz Genetic Background: involves: 102/El * C3H/Rl
MP:0004274	abnormal embryonic/fetal subventricular zone morphology	"any structural anomaly in the transient proliferative population of neurons that expands exponentially during late prenatal development; it is a continuous germinal zone distinct from the ventricular zone that surrounds the brain ventricles" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:12637172]	Show Allelic Composition: Il2rg^tm1Cgn/Y Genetic Background: involves: 129 * CB20 Allelic Composition: Pax6^Mhdaaey18/Pax6^Mhdaaey18 Genetic Background: involves: C3HeB/FeJ Allelic Composition: Emx2^tm1Sia/Emx2^tm1Sia,Pax6^Sey/Pax6^Sey Genetic Background: involves: C57BL/6 * CBA
MP:0004275	abnormal postnatal subventricular zone morphology	"any structural anomaly of the mitotically active layer of cells surrounding the brain ventricles in the adult that consists of migrating neuroblasts, astrocytes and transitory amplifying progenitor cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:12637172]	Show Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: involves: 102 * C3H
MP:0004538	abnormal maxillary shelf	"any structural anomaly of the outgrowth of the maxilla that normally fuses with palatine shelf to form secondary (hard) palate" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^Sey/Pax6^Sey-H Genetic Background: involves: 101/H * C3H/HeH * C57BL/10
MP:0004726	abnormal nasal capsule morphology	"any structural abnormality in the cartilage around the developing nasal cavity of the embryo" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Efemp1^tm1Lmar/Efemp1⁺ Genetic Background: involves: 129X1/SvJ * BALB/c Allelic Composition: Pax6^Sey/Pax6^Sey-Neu,Tg(Hbb-b1)83Clo/0 Genetic Background: involves: 102 * C3H * C57BL * CBA/Ca * CD-1 * SJL Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: CBACa.Cg-Pax6^Sey Allelic Composition: Pax6^Sey-Neu/Pax6^Sey-Neu Genetic Background: CBACa.Cg-Pax6^Sey-Neu
MP:0004761	susceptibility to induced pancreatitis	"more likely than normal to develop an inflammatory response, or an increased inflammatory response in the pancreatic tissue after experimental manipulation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:hdene "Howard Dene, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
MP:0004811	abnormal neuron physiology	"anomalous function of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:National Library of Medicine_Medical Subject Headings]	Show Allelic Composition: Pax6^tm1Pgr/Pax6^tm1Pgr Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0004948	abnormal neuronal precursor proliferation	"any anomaly in the ability of a neuroblast population to undergo rapid expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^{tm2(Pax6_i5a,Pax2)Xzh}/Pax6^{tm2(Pax6_i5a,Pax2)Xzh} Genetic Background: involves: 129S6/SvEvTac Allelic Composition: Pax6^{tm2.1(Pax6_i5a,Pax2)Xzh}/Pax6^{tm2.1(Pax6_i5a,Pax2)Xzh} Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
MP:0004979	abnormal neuronal precursor cell number	"deviation from the normal count of the neuroblast embryonic cells that develop into nerve cells or neurons" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ins2^Akita/? Genetic Background: involves: C57BL/6NSlc
MP:0005099	abnormal ciliary body morphology	"structural anomaly of the thickened portion of the vascular tunic, which lies between the choroid and the iris" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(CAG-EGFP,-Pax6,-lacZ)1Stoy/0,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0005120	decreased circulating growth hormone level	"less than the expected blood concentration of the hormone that promotes body growth, fat mobilization, and inhibition of glucose utilization" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0005128	decreased adrenocorticotropin level	"decreased concentration of adrenocorticotropic hormone " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Il6st^tm1Ern/Il6st⁺,Smad3^tm1Par/Smad3⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0005172	lack of eye pigmentation	"visual organs are devoid of coloring pigment in relation to control animals, usually resulting in a red or pink color" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500]	Show Allelic Composition: Chek1^tm1Sje/Chek1^tm1Sje,Trp53^tm1Brd/Trp53^tm1Brd Genetic Background: involves: 129S7/SvEvBrd
MP:0005193	abnormal anterior eye segment morphology	"anomalous structure of any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0005201	abnormal retinal pigment epithelium morphology	"anomaly in the epithelial layer of the retina composed of cells containing pigment granules " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey Allelic Composition: Pax6^Sey/Pax6⁺ Genetic Background: B10.Cg-Pax6^Sey Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Mitf^mi-vga9/Mitf⁺,Pax6^Sey-Neu/Pax6⁺ Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Mitf^mi-vga9/Mitf^mi-vga9,Pax6^Sey-Neu/Pax6^Sey-Neu Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Mitf^mi-vga9/Mitf^mi-vga9,Pax6^Sey-Neu/Pax6⁺ Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Mitf^tm3.1Arnh/Mitf^tm3.1Arnh,Pax6^Sey-Neu/Pax6⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6N
MP:0005205	abnormal eye anterior chamber	"anomaly of the space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^Sey-Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^tm1Pgr/Pax6⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^132-14Neu/Pax6^132-14Neu Genetic Background: C3.Cg-Pax6^132-14Neu
MP:0005208	abnormal iris stroma morphology	"structural anomaly of the lamellated connective tissue of the iris" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
MP:0005236	abnormal olfactory nerve morphology	"anomalous structure of the first cranial nerve, which conveys the sense of smell" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0005241	abnormal retinal ganglion layer morphology	"anomalous structure of the innermost nuclear layer of the retina, which projects axons through the optic nerve to the brain " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pax6^1Jrt/Pax6⁺ Genetic Background: C3.B6-Pax6^1Jrt
MP:0005253	abnormal eye physiology	"anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Rax-cre)1Zkoz/0 Genetic Background: Not Specified
MP:0005258	ocular hypertension	"abnormal elevation of the intraocular pressure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
MP:0005261	aniridia	"abnormality in which there is only a rudimentary iris, due to the failure of optic cup growth" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey Allelic Composition: Pax6^tm1Gfs/Pax6^tm1Gfs Genetic Background: involves: 129S7/SvEvBrd
MP:0005262	coloboma	"anomaly in which some of the structures of the eye are absent due to incomplete fusion of the fetal intraocular fissure during gestation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey Allelic Composition: Pax6^Sey-H/Pax6⁺ Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: Pax6^132-14Neu/Pax6^132-14Neu Genetic Background: C3.Cg-Pax6^132-14Neu Allelic Composition: Pax6^Sey-Dey/Pax6^Sey Genetic Background: involves: C3H/HeJ Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: involves: C3H/HeJ Allelic Composition: Pax6^tm1.2Xzh/Pax6^tm1.2Xzh Genetic Background: B6.129S6-Pax6^tm1.2Xzh
MP:0005293	impaired glucose tolerance	"less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Il6st^tm1Ern/Il6st⁺,Smad3^tm1Par/Smad3⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0005300	abnormal corneal stroma morphology	"structural anomaly of the lamellated connective tissue of the cornea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pax6^Sey-Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^tm1Gfs/Pax6^tm1Gfs Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Pax6^132-14Neu/Pax6⁺ Genetic Background: C3.Cg-Pax6^132-14Neu Allelic Composition: Pax6^132-14Neu/Pax6^132-14Neu Genetic Background: C3.Cg-Pax6^132-14Neu Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: B6EiC3Sn a/A-Pax6^Sey-Dey/J Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
MP:0005301	abnormal corneal endothelium morphology	"anomalous structure of the single layer of large flattened cells that cover the surface of the cornea" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pax6^132-14Neu/Pax6⁺ Genetic Background: C3.Cg-Pax6^132-14Neu Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: C.Cg-Pax6^Sey
MP:0005408	hypopigmentation	"dilution of the pigment in the body" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey
MP:0005542	corneal vascularization	"formation of blood vessels in the cornea, which normally lacks vessels" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pax6^Sey-Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: C.Cg-Pax6^Sey
MP:0005545	abnormal lens development	"aberrant formation of the transparent structure of the eye responsible for focusing light rays" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey Allelic Composition: Pax6^Sey-Neu/Pax6⁺ Genetic Background: C3.Cg-Pax6^Sey-Neu Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0006000	abnormal corneal epithelium	"malformation in the one or more of the layers of epithelial cells covering the front of the cornea" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^Sey-Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: B6EiC3Sn a/A-Pax6^Sey-Dey/J
MP:0006071	abnormal retinal progenitor morphology	"anomoly in the proliferation or differentiation of the cells that give rise to the various cells of the retina" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92622:]	Show Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Rax-cre)1Zkoz/0 Genetic Background: Not Specified
MP:0006095	absent amacrine cells	"absence or loss of the amacrine cells, which constitute one of the three types of interneurons found in the inner nuclear layer of the mature retina" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:74753]	Show Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Rax-cre)1Zkoz/0 Genetic Background: Not Specified
MP:0006104	abnormal tectum morphology	"any structural alterations or malfunction of the rostral part of the midbrain roof" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator, J:65762]	Show Allelic Composition: Emx2^tm1Sia/Emx2^tm1Sia,Pax6^Sey/Pax6^Sey Genetic Background: involves: C57BL/6 * CBA
MP:0006219	optic nerve degeneration	"retrogressive pathologic change of the optic nerve" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
MP:0006221	optic nerve hypoplasia	"less than the normal number of fibers in the optic nerve" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
MP:0006226	iris hypoplasia	"less than the normal number of cells in the iris" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey Allelic Composition: Pax6^Sey-Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^tm1Gfs/Pax6^tm1Gfs Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Pax6^tm1Gfs/Pax6⁺ Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(CAG-EGFP,-Pax6,-lacZ)1Stoy/0,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(CAG-EGFP,-Pax65a,-lacZ)1Stoy/0,Tg(Dct-cre)1Apdn/0 Genetic Background:* involves: 129S1/Sv * 129X1/SvJ
MP:0006243	abnormal pupil dilation reaction to light	"the pupil fails to constrict fully when exposed to bright light" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0006254	thin cerebral cortex	"decreased depth of the mantle covering the surface of the cerebral hemispheres" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:84683]	Show
MP:0006293	absent olfactory placodes	"absence of the paired ectodermal placodes that come to lie in the bottom of the olfactory pits as the pits are deepened by the growth of the surrounding medial and lateral nasal processes " [J:71787, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: involves: Swiss Allelic Composition: Pax6^Sey-Dey/Pax6^Sey Genetic Background: involves: C3H/HeJ
MP:0006369	supernumerary incisors	"more than a pair, top and/or bottom, of the long pointed teeth that are the most anterior and prominent in the jaw" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Efemp1^tm1Lmar/Efemp1⁺ Genetic Background: involves: 129X1/SvJ * BALB/c Allelic Composition: Pax6^Sey/Pax6^Sey-Neu,Tg(Hbb-b1)83Clo/0 Genetic Background: involves: 102 * C3H * C57BL * CBA/Ca * CD-1 * SJL
MP:0008128	abnormal brain internal capsule morphology	"any structural anomaly of the area of white matter in the brain that lies between the lenticular and caudate nuclei, and contains a group of myelinated ascending and descending axonal fiber tracts that connects the cerebral cortex to the brain stem and spinal cord" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^tm1Ued/Pax6^tm1Ued,Tg(Six3-cre)69Frty/0 Genetic Background: involves: 129P2/OlaHsd * ICR
MP:0008439	abnormal cortical plate morphology	"any strucutral anomaly of the outer neural tube region in which post-mitotic neuroblasts migrate along radial glia to form the adult cortical layers" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:1812236]	Show Allelic Composition: Pax6^{tm2.1(Pax6_i5a,Pax2)Xzh}/Pax6^{tm2.1(Pax6_i5a,Pax2)Xzh} Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
MP:0008441	thin cortical plate	"reduced thickness of the outer neural tube region in which post-mitotic neuroblasts migrate along radial glia to form the adult cortical layers" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:1812236]	Show Allelic Composition: Il2rg^tm1Cgn/Y Genetic Background: involves: 129 * CB20 Allelic Composition: Pax6^Mhdaaey18/Pax6^Mhdaaey18 Genetic Background: involves: C3HeB/FeJ Allelic Composition: Pax6^{tm2(Pax6_i5a,Pax2)Xzh}/Pax6^{tm2(Pax6_i5a,Pax2)Xzh} Genetic Background: involves: 129S6/SvEvTac
MP:0008458	abnormal cortical ventricular zone morphology	"any structural anomaly of a transient region of the developing cerebral cortex that contains migrating neurons, radial glial cells, and a large population of cycling multipotent neural stem cells that generate newborn neurons" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: involves: 102 * C3H
MP:0008521	abnormal Bowman membrane	"any structural anomaly of the layer of acellular matrix that lies beneath the corneal epithelium and above the corneal stroma, consists of randomly arranged collagen fibers in a condensed bed of intercellular substance, and provides stability and strength to the cornea" [MESH:A09.371.060.217.113]	Show Allelic Composition: Pax6^Sey-Neu/Pax6⁺ Genetic Background: involves: 102 * C3H
MP:0008547	abnormal neocortex morphology	"any structural anomaly of the larger part of the mammalian cerebral cortex, distinguished from the allocortex by being composed of a larger number of nerve cells arranged in six layers" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A08.186.211.730.885.213.420]	Show Allelic Composition: Ins2^Akita/? Genetic Background: involves: C57BL/6NSlc
MP:0008789	abnormal olfactory epithelium morphology	"any structural anomaly in the epithelial cells that line the interior of the nose" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0008794	increased lens epithelium apopotosis	"increase in the number of lens epithelial cells undergoing programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Sox2^tm1.1Lan/Sox2^tm1.1Lan,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
MP:0008934	absent choroid plexus	"absence of the fringe of the tela choroidea of the brain ventricles" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Emx2^tm1Sia/Emx2^tm1Sia,Pax6^Sey/Pax6^Sey Genetic Background: involves: C57BL/6 * CBA
MP:0008946	abnormal neuron number	"anomaly in the number of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:A08.663]	Show Allelic Composition: Ins2^Akita/? Genetic Background: involves: C57BL/6NSlc Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Smarcc2^tm1.1Stoy/Smarcc2^tm1.1Stoy,Emx1^tm1(cre)Krj/Emx1⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6
MP:0009174	absent pancreatic beta cells	"absence of the cells of the pancreas that secrete insulin" [MESH:A03.734.414.131]	Show Allelic Composition: Kit^tm1Alf/Kit⁺ Genetic Background: involves: 129S2/SvPas
MP:0009177	decreased pancreatic alpha cell number	"reduction in the number of the cells of the pancreas that secrete glucagon" [MESH:A03.734.414.065]	Show Allelic Composition: Pax6^tm1Pgr/Pax6^tm2Pgr,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB * NMRI Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: FVB * NMRI Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Pdx1-cre)6Cvw/0 Genetic Background: involves: FVB * NMRI
MP:0009178	absent pancreatic alpha cells	"absence of the cells of the pancreas that secrete glucagon" [MESH:A03.734.414.065]	Show Allelic Composition: Pax6^tm1Pgr/Pax6^tm1Pgr Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI Allelic Composition: Pax6^Sey-Neu/Pax6^Sey-Neu Genetic Background: involves: 102 * C3H * CD-1
MP:0009254	disorganized pancreatic islets	"derangement of the normal pattern of the hormone-producing cells within an islet; normally, the beta cells occupy the central portion of the islet and are surrounded by a corona of alpha and delta cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^tm1Pgr/Pax6^tm1Pgr Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI
MP:0009265	delayed eyelid fusion	"later than average time of the joining of the upper and lower thin folds of skin and muscle that cover the exposed portion of the eye" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0009522	submandibular gland hypoplasia	"underdevelopment or reduced size of either of the large major salivary glands situated beneath the mandible, usually due to reduced cell number" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0009637	abnormal pretectal region morphology	"any structural anomaly of a narrow, transversely oriented rostral zone of the mesencephalic tectum, bounded caudally by the superior colliculus, rostrally by the habenular trigone, and laterally by the pulvinar thalami; the pretectal area contains several nuclei that receive fibers from the optic tract; it has bilateral efferent connections with the Edinger-Westphal nucleus of the oculomotor nuclear complex by way of which it mediates the pupillary light reflex" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Emx2^tm1Sia/Emx2^tm1Sia,Pax6^Sey/Pax6^Sey Genetic Background: involves: C57BL/6 * CBA
MP:0009703	decreased birth body size	"reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^Coop/Pax6⁺ Genetic Background: C3.D2-Pax6^Coop Allelic Composition: Pax6^Sey-3H/Pax6⁺ Genetic Background: Not Specified
MP:0009725	absent lens vesicle	"absence of the ectodermal invagination that forms opposite the optic cup in the primordium of the lens of the eye" [ISBN:0-12-402035-6 "Kaufman, MH The Atlas of Mouse Development", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: involves: Swiss Allelic Composition: Pax6^Sey-Dey/Pax6^Sey Genetic Background: involves: C3H/HeJ Allelic Composition: Pax6^tm1.1Zkoz/Pax6^Sey-Neu,Tg(Rax-cre)1Zkoz/0 Genetic Background: involves: 102/El * C3H/Rl
MP:0009772	abnormal retinal development	"anomaly in any of the steps during embryogenesis that produce the nerve layer lining in the back of the eye which senses light, and creates impulses that travel through the optic nerve to the brain" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^{tm2(Pax6_i5a,Pax2)Xzh}/Pax6^{tm2(Pax6_i5a,Pax2)Xzh} Genetic Background: involves: 129S6/SvEvTac Allelic Composition: Pax6^{tm2.1(Pax6_i5a,Pax2)Xzh}/Pax6^{tm2.1(Pax6_i5a,Pax2)Xzh} Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Rax-cre)1Zkoz/0 Genetic Background: Not Specified Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Pax6-cre,GFP)2Pgr/0 Genetic Background: Not Specified
MP:0009859	eye opacity	"changes in the eye grossly observed as a milky or cloudy appearance that may be progressive and persistent throughout life" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: involves: 102 * C3H
MP:0009902	abnormal lateral nasal prominence morphology	"any structural anomaly of the lateral area of the two branches of a horseshoe-shaped mesenchymal swelling in the future nasal region of the embryo; it separates the olfactory pit from the developing eye and the ala of the nose/snout develops from it" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Pax6^4Neu/Pax6^4Neu Genetic Background: either: (involves: 102 * C3H) or (involves: C3H)
MP:0009903	abnormal medial nasal prominence morphology	"any structural anomaly of the central area of the two limbs of a horseshoe-shaped mesenchymal swelling that lie medial to the olfactory placode or pit in the future nasal region of the embryo; it joins with the ipsilateral maxillary prominence in the formation of half of the upper jaw, and the nasal tip and philtrum of the upper lip develop from it" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Pax6^4Neu/Pax6^4Neu Genetic Background: either: (involves: 102 * C3H) or (involves: C3H)
MP:0009937	abnormal neuron differentiation	"abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: involves: C57BL/6J * DBA/2J Allelic Composition: Pax6^Mhdaaey18/Pax6^Mhdaaey18 Genetic Background: involves: C3HeB/FeJ Allelic Composition: Gli2^tm1Alj/Gli2^tm1Alj,Pax6^Sey/Pax6^Sey Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0010259	anterior polar cataracts	"a lens opacity, usually disk-shaped, that is limited to an area in the anterior pole of the lens capsular region" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]	Show Allelic Composition: Pax6^6Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^4Neu/Pax6⁺ Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^7Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^2Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^5Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^132-14Neu/Pax6⁺ Genetic Background: C3.Cg-Pax6^132-14Neu
MP:0010292	increased alimentary system tumor incidence	"greater than the expected number of tumors originating in the alimentary system in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
MP:0010301	increased stomach tumor incidence	"greater than the expected number of neoplasms in the gastric tissue usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
MP:0010713	corneal-lenticular stalk	"persistent central adhesion between the lens and the cornea" [PMID:18653562]	Show Allelic Composition: Pax6^Mhdaaey18/Pax6⁺ Genetic Background: C3HeB/FeJ-Pax6^Mhdaaey18 Allelic Composition: Pax6^Mhdaaey11/Pax6^Mhdaaey11 Genetic Background: C3HeB/FeJ-Pax6^Mhdaaey11 Allelic Composition: Pax6^tm1.2Xzh/Pax6^tm1.2Xzh Genetic Background: B6.129S6-Pax6^tm1.2Xzh Allelic Composition: Pax6^Aey80/Pax6⁺ Genetic Background: C3HeB/FeJ-Pax6^Aey80 Allelic Composition: Pax6^{tm2.1(Pax6_i5a,Pax2)Xzh}/Pax6⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
MP:0011085	complete postnatal lethality	"premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Pax6^4Neu/Pax6^4Neu Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^tm1Pgr/Pax6^tm2Pgr,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB * NMRI Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: FVB * NMRI Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Pdx1-cre)6Cvw/0 Genetic Background: involves: FVB * NMRI
MP:0011086	partial postnatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Pax6^Coop/Pax6⁺ Genetic Background: C3.D2-Pax6^Coop Allelic Composition: Pax6^Sey-3H/Pax6⁺ Genetic Background: Not Specified
MP:0011087	complete neonatal lethality	"death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: Pax6^tm1Pgr/Pax6^tm1Pgr Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI Allelic Composition: Pax6^Mhdaaey18/Pax6^Mhdaaey18 Genetic Background: involves: C3HeB/FeJ Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: involves: C57BL/6
MP:0011088	partial neonatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]	Show Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey
MP:0011089	complete perinatal lethality	"death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]	Show Allelic Composition: Pax6^Aey80/Pax6^Aey80 Genetic Background: C3HeB/FeJ-Pax6^Aey80
MP:0011090	partial perinatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]	Show Allelic Composition: Pax6^Coop/Pax6⁺ Genetic Background: C3.D2-Pax6^Coop Allelic Composition: Pax6^Sey-3H/Pax6⁺ Genetic Background: Not Specified Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: B10.Cg-Pax6^Sey
MP:0011091	complete prenatal lethality	"death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]	Show Allelic Composition: Pax6^Coop/Pax6^Coop Genetic Background: C3.D2-Pax6^Coop
MP:0011092	complete embryonic lethality	"death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]	Show Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: C3H/HeJ-Pax6^Sey-Dey
MP:0011096	complete embryonic lethality before somite formation	"death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]	Show Allelic Composition: Pax6^Sey-3H/Pax6⁺ Genetic Background: Not Specified
MP:0011101	partial prenatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]	Show Allelic Composition: Pax6^Sey-Dey/Pax6⁺ Genetic Background: involves: C3H/HeJ
MP:0011102	partial embryonic lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]	Show Allelic Composition: Pax6^Coop/Pax6⁺ Genetic Background: C3.D2-Pax6^Coop
MP:0011104	partial embryonic lethality before implantation	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]	Show Allelic Composition: Pax6^Coop/Pax6⁺ Genetic Background: C3.D2-Pax6^Coop
MP:0011481	anterior iris synechia	"adhesion of the iris to the cornea" [MGI:anna]	Show Allelic Composition: Pax6^Sey-Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^tm1Pgr/Pax6⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^1Jrt/Pax6⁺ Genetic Background: C3.B6-Pax6^1Jrt Allelic Composition: Pax6^6Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^3Neu/Pax6⁺ Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^4Neu/Pax6⁺ Genetic Background: either: (involves: 102 * C3H) or (involves: C3H) Allelic Composition: Pax6^7Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^2Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^5Neu/Pax6⁺ Genetic Background: involves: 102 * C3H Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: C.Cg-Pax6^Sey Allelic Composition: Pax6^tm2Pgr/Pax6⁺,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
MP:0011932	abnormal endocrine pancreas development		Show Allelic Composition: Pax6^Sey-H/Pax6⁺ Genetic Background: involves: 101/H * C3H/HeH
MP:0011965	decreased total retina thickness	"decreased width of the retina through the center plane" [MGI:csmith]	Show Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Rax-cre)1Zkoz/0 Genetic Background: Not Specified
MP:0012168	abnormal optic placode morphology	"any structural anomaly of the paired thickenings of surface ectoderm that become invaginated to form the embryonic lens vesicles" [MGI:anna]	Show Allelic Composition: Pax6^tm1Lan/Pax6^tm1Lan Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm1Lan/Pax6⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax6^tm1.1Zkoz/Pax6^Sey-Neu,Tg(Rax-cre)1Zkoz/0 Genetic Background: involves: 102/El * C3H/Rl
MP:0012170	absent optic placodes	"absence of the paired thickenings of surface ectoderm that normally become invaginated to form the embryonic lens vesicles" [MGI:anna]	Show Allelic Composition: Pax6^tm1Pgr/Pax6^tm2Pgr,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB * NMRI
MP:0012517	absent diencephalon	"absence or loss of the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex" [MGI:anna]	Show Allelic Composition: Emx2^tm1Sia/Emx2^tm1Sia,Pax6^Sey/Pax6^Sey Genetic Background: involves: C57BL/6 * CBA
MP:0013742	absent ciliary body	"absence of the thickened portion of the vascular tunic, which lies between the choroid and the iris" [ISBN:0-683-40008-8, MGI:Anna]	Show Allelic Composition: Pax6^tm2Pgr/Pax6^tm2Pgr,Tg(Dct-cre)1Apdn/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0013791	absent external nares	"absence or failure to form both of the anterior openings to the nasal cavity" [MGI:Anna]	Show Allelic Composition: Pax6^Coop/Pax6^Coop Genetic Background: C3.D2-Pax6^Coop
MP:0020527	small thalamus	"decreased size of the thalamus" [MGI:smb]	Show
MP:0030005	increased retinal apoptosis	"increase in the number of cells in the retina undergoing programmed cell death" [MGI:anna]	Show Allelic Composition: Pax6^tm1.1Zkoz/Pax6^tm1.1Zkoz,Tg(Rax-cre)1Zkoz/0 Genetic Background: Not Specified
MP:0030060	absent nasal pit	"absence of one or both of a pair of depressions formed in the developing face that give rise to the rostral portion of the nasal meatus; the nasal pits indent the frontonasal process and divide it into a medial and two lateral nasal processes" [MGI:anna]	Show Allelic Composition: Pax6^Sey/Pax6^Sey Genetic Background: B10.Cg-Pax6^Sey
MP:0030313	abnormal face development	"any anomaly in the process in which the anatomical structures of the face are generated and organized" [GO:0060325]	Show Allelic Composition: Pax6^Sey/Pax6^Sey-H Genetic Background: involves: 101/H * C3H/HeH * C57BL/10

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr

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