Manteia

ID	Phenotype	Definition	Genetic BG
MP:0000097	short maxilla	"reduced length of the upper jaw bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370]	Show Allelic Composition: Hoxa3^tm1Mrc/Hoxa3^tm1Mrc,Hoxb3^tm1Mrc/Hoxb3^tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J Allelic Composition: Pax7^tm2Pgr/Pax7^tm2Pgr Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S2/SvPas)
MP:0000428	abnormal craniofacial morphology	"anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Gt(ROSA)26Sor^{tm4(EWSR1/ATF1)Mrc}/Gt(ROSA)26Sor⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0000448	pointed snout	"nose tapers to a small tip, sharper angle than wild type " [J:18378]	Show Allelic Composition: Hoxa3^tm1Mrc/Hoxa3^tm1Mrc,Hoxb3^tm1Mrc/Hoxb3^tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J Allelic Composition: Pax7^tm2Pgr/Pax7^tm2Pgr Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S2/SvPas)
MP:0000457	maxilla hypoplasia	"arrested growth or atrophy of the upper bony framework of the mouth where the superior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637]	Show Allelic Composition: Pax3^tm1Mrc/Pax3⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0000496	abnormal small intestine morphology	"structural or developmental anomalies of the intestinum tenue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pax7^tm2Pgr/Pax7^tm2Pgr Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S2/SvPas)
MP:0000729	abnormal myogenesis	"anomaly in embryonic formation of muscle cells or fibers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺,Pax7^tm1.1Fan/Pax7^{tm2.1(cre/ERT2)Fan} Genetic Background: involves: 129 * C57BL/6 * SJL
MP:0000733	abnormal muscle development	"anomalous differentiation of muscle tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Gt(ROSA)26Sor^tm2(SS18)Mrc/Gt(ROSA)26Sor^tm2(SS18)Mrc,Pax7^tm1(cre)Mrc/Pax7^tm1(cre)Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0000734	muscle hypoplasia	"underdevelopment or atrophy of muscle" [J:15108]	Show Allelic Composition: Pax3^tm1Mrc/Pax3⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0000737	abnormal myotome development	"malformation of or absence of the part of the somite that develops into the musculature" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:29279]	Show Allelic Composition: Pax3^tm1Buck/Pax3^tm1Buck,Pax7^tm2Pgr/Pax7^tm2Pgr Genetic Background: either: (involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ) or (involves: 129P2/OlaHsd * 129S2/SvPas)
MP:0000747	muscle weakness	"loss of muscle strength" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Hoxa3^tm1Mrc/Hoxa3^tm1Mrc,Hoxb3^tm1Mrc/Hoxb3^tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
MP:0000750	abnormal muscle regeneration	"inability or defects in ability to repair muscle after injuries" [J:42574]	Show Allelic Composition: Hoxa3^tm1Mrc/Hoxa3^tm1Mrc,Hoxb3^tm1Mrc/Hoxb3^tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J Allelic Composition: Pax7^tm2Pgr/Pax7^tm2Pgr Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S2/SvPas * C57BL/6) Allelic Composition: Pax7^tm1.2Fan/Pax7^tm1.2Fan Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺,Pax7^tm1.1Fan/Pax7^{tm2.1(cre/ERT2)Fan} Genetic Background: involves: 129 * C57BL/6 * SJL Allelic Composition: Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺,Gt(ROSA)26Sor^tm1(DTA)Mrc/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 Allelic Composition: Pax7^{tm1.1(HBEGF)Mal}/Pax7⁺ Genetic Background: involves: C57BL/6 Allelic Composition: Pax7^{tm1.1(HBEGF)Mal}/Pax7⁺,Tg(Pax7-EGFP)#Tajb/0 Genetic Background: involves: C57BL/6 * SJL/J Allelic Composition: Six1^tm2.1Mair/Six1^tm2.1Mair,Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6Cr * C57BL/6NTac Allelic Composition: Pax7^tm1.1Thbr/Pax7^{tm2.1(cre/ERT2)Fan} Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0000751	myopathy	"any abnormal condition or disease of the skeletal muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:42574]	Show Allelic Composition: Gt(ROSA)26Sor^{tm4(EWSR1/ATF1)Mrc}/Gt(ROSA)26Sor⁺,Myf5^tm1(cre)Mrc/Myf5⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0000759	abnormal skeletal muscle morphology	"anomalous structure of any of the striated muscle fibers connected at either or both extremeties with the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pax7^tm1.1Thbr/Pax7^{tm2.1(cre/ERT2)Fan} Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0000761	thin diaphragm muscle	"reduced thickness of the diaphragm muscle" [MGI:CLS, J:60159]	Show Allelic Composition: Hoxa3^tm1Mrc/Hoxa3^tm1Mrc,Hoxb3^tm1Mrc/Hoxb3^tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Pax3^tm1Mrc/Pax3⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Eef2^tm1.1Lepp/Eef2⁺ Genetic Background: involves: C57BL/6 Allelic Composition: Pax7^tm1.1Thbr/Pax7^tm1.1Thbr,Myf5^tm3(cre)Sor/Myf5⁺ Genetic Background: involves: 129S4/SvJaeSor
MP:0001393	ataxia	"inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]	Show Allelic Composition: Galc^twi/Galc^twi Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CE/J
MP:0001732	postnatal growth retardation	"slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Hoxa3^tm1Mrc/Hoxa3^tm1Mrc,Hoxb3^tm1Mrc/Hoxb3^tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J Allelic Composition: Pax3^tm1Mrc/Pax3⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax7^tm2Pgr/Pax7^tm2Pgr Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S2/SvPas)
MP:0002020	increased tumor incidence	"greater than average number of tumors, usually a specific type" [MGI:cls, J:34193]	Show Allelic Composition: Kras^tm4Tyj/Kras⁺,Pax7^{tm2.1(cre/ERT2)Fan}/Pax7⁺,Trp53^tm1Brn/Trp53^tm1Brn Genetic Background: involves: 129/Sv * 129P2/OlaHsd * 129X1/SvJ * C57BL/6
MP:0002032	sarcoma	"connective tissue neoplasm associated with the proliferation of mesodermal cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877]	Show Allelic Composition: Kras^tm4Tyj/Kras⁺,Pax7^{tm2.1(cre/ERT2)Fan}/Pax7⁺,Trp53^tm1Brn/Trp53^tm1Brn Genetic Background: involves: 129/Sv * 129P2/OlaHsd * 129X1/SvJ * C57BL/6 Allelic Composition: Cdkn2a^tm1Cjs/Cdkn2a^tm1Cjs,Pax7^tm1Pgr/Pax7^tm1Pgr,Tg(CKMM-tTA)A3Rhvh/0,Tg(tetO-Hgf,-EGFP)24Tcre/0 Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * FVB Allelic Composition: Cdkn2a^tm1Cjs/Cdkn2a^tm1Cjs,Pax7^tm1Pgr/Pax7⁺,Tg(CKMM-tTA)A3Rhvh/0,Tg(tetO-Hgf,-EGFP)24Tcre/0 Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * FVB
MP:0002036	rhabdomyosarcoma	"malignant tumor derived from skeletal (striated) muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58877]	Show Allelic Composition: Cdkn2a^tm1Cjs/Cdkn2a⁺,Tg(CKMM-tTA)A3Rhvh/0,Tg(tetO-Hgf,-EGFP)24Tcre/0 Genetic Background: involves: 129X1/SvJ * FVB Allelic Composition: Cdkn2a^tm1Cjs/Cdkn2a^tm1Cjs,Pax7^tm1Pgr/Pax7⁺,Tg(CKMM-tTA)A3Rhvh/0,Tg(tetO-Hgf,-EGFP)24Tcre/0 Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * FVB
MP:0002083	premature death	"death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Hoxa3^tm1Mrc/Hoxa3^tm1Mrc,Hoxb3^tm1Mrc/Hoxb3^tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J Allelic Composition: Pax3^tm1Mrc/Pax3⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax7^{tm1.1(HBEGF)Mal}/Pax7^{tm1.1(HBEGF)Mal} Genetic Background: involves: C57BL/6
MP:0002106	abnormal muscle physiology	"anomolous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Aicda^tm1Hon/Aicda^tm1Hon,Bcl6^tm1.1Jwan/Bcl6^tm1.1Jwan Genetic Background: involves: 129S6/SvEvTac * C57BL/6NCrlj * CBA/JNCrlj
MP:0002108	abnormal muscle morphology	"abnormal development of muscle tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Adgrf5^tm1Shiro/Adgrf5^tm1Shiro Genetic Background: B6.Cg-Adgrf5^tm1Shiro
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pax3^tm1Mrc/Pax3⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax7^{tm1(cre/Esr1)Cklr}/Pax7^{tm1(cre/Esr1)Cklr} Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Gt(ROSA)26Sor^{tm1.1(DUX4)Plj}/Gt(ROSA)26Sor⁺,Pax7^{tm1(cre/ERT2)Gaka}/? Genetic Background:* involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl
MP:0002233	abnormal nose morphology	"any structural anomaly of the organ that is specialized for smell and is part of the respiratory system " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pax3^tm1Mrc/Pax3⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0002820	abnormal premaxilla morphology	"malformation or absence of the anterior and inner portion of the maxilla" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:76662]	Show Allelic Composition: Pax3^tm1Mrc/Pax3⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0003833	decreased number of satellite cells	"less than the normal number of unfused cells in muscle that play a role in muscle regeneration" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Pax3^tm1Mrc/Pax3⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax7^tm2Pgr/Pax7^tm2Pgr Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S2/SvPas * C57BL/6) Allelic Composition: Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺,Gt(ROSA)26Sor^tm1(DTA)Mrc/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 Allelic Composition: Pax7^{tm1.1(HBEGF)Mal}/Pax7⁺,Tg(Pax7-EGFP)#Tajb/0 Genetic Background: involves: C57BL/6 * SJL/J Allelic Composition: Pax7^tm1.1Thbr/Pax7^tm1.1Thbr,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: BALB/cJ Allelic Composition: Pax7^tm1.1Thbr/Pax7^{tm2.1(cre/ERT2)Fan} Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax7^tm1.1Thbr/Pax7^tm1.1Thbr,Myf5^tm1(cre)Mrc/Myf5⁺ Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ Allelic Composition: Myf5^tm1(cre)Mrc/Myf5⁺,Myod1^tm1Jae/Myod1^tm1Jae,Pax7^tm1.1Thbr/Pax7^tm1.1Thbr Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ Allelic Composition: Pax7^tm1.1Thbr/Pax7^tm1.1Thbr,Myf5^tm3(cre)Sor/Myf5⁺ Genetic Background: involves: 129S4/SvJaeSor
MP:0003852	skeletal muscle necrosis	"pathological cell death in the skeletal muscle, usually due to irreversible damage" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Pax7^tm1.1Thbr/Pax7^{tm2.1(cre/ERT2)Fan} Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0004477	turbinate hypoplasia	"underdevelopment or reduced size, usually due to a reduced number of cells, in the small curved bones that extends horizontally along the lateral wall of the nasal passage" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Pax3^tm1Mrc/Pax3⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0004510	myositis	"inflammation of skeletal muscle; local accumulation of fluid, plasma proteins, and leukocytes in the striated muscle" [MESH:C05.651.594]	Show Allelic Composition: Pax7^{tm1.1(HBEGF)Mal}/Pax7⁺ Genetic Background: involves: C57BL/6
MP:0004726	abnormal nasal capsule morphology	"any structural abnormality in the cartilage around the developing nasal cavity of the embryo" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Hoxa3^tm1Mrc/Hoxa3^tm1Mrc,Hoxb3^tm1Mrc/Hoxb3^tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J Allelic Composition: Pax7^tm2Pgr/Pax7^tm2Pgr Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S2/SvPas)
MP:0004819	decreased skeletal muscle mass	"reduction in the physical bulk, or total amount of matter contained within skeletal muscle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax3^tm1Mrc/Pax3⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax7^{tm1.1(HBEGF)Mal}/Pax7⁺ Genetic Background: involves: C57BL/6
MP:0005150	cachexia	"general weight loss and wasting occurring in the course of chronic disease" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Eef2^tm1.1Lepp/Eef2⁺ Genetic Background: involves: C57BL/6
MP:0005247	abnormal extraocular muscle morphology	"structural anomaly of any of the striated muscles that move the eye and include: superior rectus, inferrior rectus, medial rectus, lateral rectus, superior oblique, inferior oblique, retractor bulbi" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Myf5^tm2Tajb/Myf5^tm2Tajb,Myf6^tm1Tajb/Myf6^tm1Tajb Genetic Background: involves: 129S2/SvPas
MP:0006283	medulloblastoma	"a solid, cancerous tumor originating in the cerebellum of the brain and of primitive neuroectodermal origin " [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Galc^twi/Galc^twi Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CE/J Allelic Composition: Ptch1^tm1Cklr/Ptch1⁺,Trp53^tm1Brn/?,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
MP:0008052	abnormal serous gland morphology	"any structural anomaly of glands that secrete watery albuminous material that often contains enzymes" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Hoxa3^tm1Mrc/Hoxa3^tm1Mrc,Hoxb3^tm1Mrc/Hoxb3^tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J Allelic Composition: Pax7^tm2Pgr/Pax7^tm2Pgr Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S2/SvPas)
MP:0009398	abnormal skeletal muscle fiber size	"anomaly in the size of the large multinucleated cells that make up the skeletal muscles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax7^{tm1.1(rtTA)Sjl}/Pax7^{tm1.1(rtTA)Sjl} Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0009402	decreased skeletal muscle fiber diameter	"decreased width of the cross-sectional distance that extends from one lateral edge of a skeletal muscle fiber, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Hoxa3^tm1Mrc/Hoxa3^tm1Mrc,Hoxb3^tm1Mrc/Hoxb3^tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J Allelic Composition: Pax3^tm1Mrc/Pax3⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax7^tm1.1Thbr/Pax7^tm1.1Thbr,Myf5^tm3(cre)Sor/Myf5⁺ Genetic Background: involves: 129S4/SvJaeSor
MP:0009406	decreased skeletal muscle fiber number	"decreased number of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax7^tm1.1Thbr/Pax7^tm1.1Thbr,Myf5^tm3(cre)Sor/Myf5⁺ Genetic Background: involves: 129S4/SvJaeSor
MP:0009407	increased skeletal muscle fiber density	"increase in the number of skeletal muscle fibers in a given cross-sectional area of a skeletal muscle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax3^tm1Mrc/Pax3⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0009410	abnormal skeletal muscle satellite cell proliferation	"anomaly in the ability of unfused cells in skeltal muscle to undergo expansion by cell division, usually triggered by injury or disease" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax7^tm1.1Thbr/Pax7^{tm2.1(cre/ERT2)Fan} Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Pax7^tm1.1Thbr/Pax7^tm1.1Thbr Genetic Background: Not Specified
MP:0009419	skeletal muscle fibrosis	"formation of fibrous tissue within skeletal muscle as a result of repair or a reactive process" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Pax7^tm1.2Fan/Pax7^tm1.2Fan Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺,Gt(ROSA)26Sor^tm1(DTA)Mrc/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 Allelic Composition: Six1^tm2.1Mair/Six1^tm2.1Mair,Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6Cr * C57BL/6NTac Allelic Composition: Pax7^tm1.1Thbr/Pax7^{tm2.1(cre/ERT2)Fan} Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0009703	decreased birth body size	"reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax7^{tm1.1(HBEGF)Mal}/Pax7^{tm1.1(HBEGF)Mal} Genetic Background: involves: C57BL/6
MP:0010053	decreased grip strength	"reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]	Show Allelic Composition: Nphp1^{tm1.1(KOMP)Vlcg}/Nphp1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Nphp1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0010238	increased skeletal muscle weight	"greater than average skeletal muscle weight" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax7^{tm1.1(rtTA)Sjl}/Pax7^{tm1.1(rtTA)Sjl} Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0010239	decreased skeletal muscle weight	"less than average skeletal muscle weight" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Eef2^tm1.1Lepp/Eef2⁺ Genetic Background: involves: C57BL/6
MP:0010240	decreased skeletal muscle size	"less than average dimensions of one or more of the muscles of the skeleton" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax7^tm1.1Thbr/Pax7^{tm2.1(cre/ERT2)Fan} Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0011086	partial postnatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Hoxa3^tm1Mrc/Hoxa3^tm1Mrc,Hoxb3^tm1Mrc/Hoxb3^tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J Allelic Composition: Pax7^tm2Pgr/Pax7^tm2Pgr Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S2/SvPas) Allelic Composition: Pax7^{tm1.1(rtTA)Sjl}/Pax7^{tm1.1(rtTA)Sjl} Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0011091	complete prenatal lethality	"death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]	Show Allelic Composition: Pax3^tm1Buck/Pax3^tm1Buck,Pax7^tm2Pgr/Pax7^tm2Pgr Genetic Background: either: (involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ) or (involves: 129P2/OlaHsd * 129S2/SvPas)
MP:0011099	complete lethality throughout fetal growth and development	"death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]	Show Allelic Composition: Gt(ROSA)26Sor^{tm3(SS18/EGFP)Mrc}/Gt(ROSA)26Sor^{tm3(SS18/EGFP)Mrc},Myf6^tm1(cre)Mrc/Myf6^tm1(cre)Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Gt(ROSA)26Sor^{tm3(SS18/EGFP)Mrc}/Gt(ROSA)26Sor^{tm3(SS18/EGFP)Mrc},Pax7^tm1(cre)Mrc/Pax7^tm1(cre)Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Gt(ROSA)26Sor^{tm4(EWSR1/ATF1)Mrc}/Gt(ROSA)26Sor⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0011110	partial preweaning lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Nampt^{tm1.1(KOMP)Vlcg}/Nampt^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Nampt^{tm1.1(KOMP)Vlcg}/Ucd
MP:0012185	abnormal muscle precursor cell morphology	"any structural anomaly of cells that will develop into muscle cells" [MGI:mnk]	Show Allelic Composition: Atp6ap2^tm1.1Ics/Y Genetic Background: involves: C57BL/6 * C57BL/6N Allelic Composition: Kdm6a^tm1.1Kaig/Y,Pax7^{tm2.1(cre/ERT2)Fan}/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0013239	impaired skeletal muscle regeneration	"reduced ability to repair skeletal muscle after injury or disease" [MGI:csmith]	Show Allelic Composition: Mamstr^tm1.1Eno/Mamstr^tm1.1Eno,Pax7^{tm2.1(cre/ERT2)Fan}/Pax7⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Pax7^tm1.1Thbr/Pax7^tm1.1Thbr,Myf5^tm3(cre)Sor/Myf5⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Kdm6a^tm1.1Kaig/Kdm6a^tm1.1Kaig,Pax7^{tm2.1(cre/ERT2)Fan}/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}/Gt(ROSA)26Sor⁺,Kdm6a^tm1.1Kaig/Y,Pax7^{tm2.1(cre/ERT2)Fan}/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Kdm6a^tm1.1Kaig/Y,Pax7^{tm2.1(cre/ERT2)Fan}/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0030056	lacrimal bone hypoplasia	"underdevelopment or reduced size, usually due to a reduced number of cells, of the thin plate that forms part of the medial wall of the orbit behind the frontal process of the maxilla" [MGI:anna]	Show Allelic Composition: Pax3^tm1Mrc/Pax3⁺,Pax7^tm1(cre)Mrc/Pax7⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr

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