Manteia

ENSMUSG00000037034

Mus musculus

Features

Gene ID:	ENSMUSG00000037034

Biological name :	Pax1

Synonyms :	P09084 / Paired box protein Pax-1 / Pax1

Possible biological names infered from orthology :	P15863 / paired box 1

Species:	Mus musculus

Chr. number:	2
Strand:	1
Band:	G2
Gene start:	147361925
Gene end:	147393295

Corresponding Affymetrix probe sets:	10476874 (MoGene1.0st) 1443476_at (Mouse Genome 430 2.0 Array) 1449359_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000119667 Ensembl peptide - ENSMUSP00000105594 NCBI entrez gene - 18503 See in Manteia. MGI - MGI:97485 RefSeq - NM_008780 RefSeq - XM_006498911 RefSeq Peptide - NP_032806 swissprot - A2ALK0 swissprot - P09084 Ensembl - ENSMUSG00000037034

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
pax1a	ENSDARG00000008203	Danio rerio
pax1b	ENSDARG00000073814	Danio rerio
PAX1	ENSGALG00000039040	Gallus gallus
PAX1	ENSG00000125813	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Pax9 / P47242 / Paired box protein Pax-9 / P55771* / paired box 9*	ENSMUSG00000001497	49
Pax2 / paired box 2 / Q02962*	ENSMUSG00000004231	33
Pax8 / Q00288 / Paired box protein Pax-8 / Q06710* / paired box 8*	ENSMUSG00000026976	32
Pax7 / P47239 / Paired box protein Pax-7 / P23759* / paired box 7*	ENSMUSG00000028736	31
Pax5 / Q02650 / Paired box protein Pax-5 / Q02548* / paired box 5*	ENSMUSG00000014030	31
Pax3 / P24610 / paired box 3 / P23760*	ENSMUSG00000004872	30
Pax6 / P63015 / Paired box protein Pax-6 / P26367* / paired box 6*	ENSMUSG00000027168	28
Pax4 / P32115 / paired box 4 / O43316*	ENSMUSG00000029706	21

Protein motifs (from Interpro)

Interpro ID	Name
IPR001523	Paired domain
IPR009057	Homeobox-like domain superfamily
IPR033206	Paired box protein PAX1
IPR036388	Winged helix-like DNA-binding domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001501	skeletal system development	IMP
biological_process	GO:0001756	somitogenesis	IMP
biological_process	GO:0006351	transcription, DNA-templated	IEA
biological_process	GO:0006355	regulation of transcription, DNA-templated	TAS
biological_process	GO:0006366	transcription by RNA polymerase II	IEA
biological_process	GO:0007275	multicellular organism development	IEA
biological_process	GO:0007389	pattern specification process	IMP
biological_process	GO:0008283	cell proliferation	IMP
biological_process	GO:0009887	animal organ morphogenesis	TAS
biological_process	GO:0043367	CD4-positive, alpha-beta T cell differentiation	IMP
biological_process	GO:0043374	CD8-positive, alpha-beta T cell differentiation	IMP
biological_process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA
biological_process	GO:0048538	thymus development	IGI
biological_process	GO:0060017	parathyroid gland development	IGI
biological_process	GO:0060349	bone morphogenesis	IMP
biological_process	GO:0061056	sclerotome development	IEP
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005667	transcription factor complex	TAS
molecular_function	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	IMP
molecular_function	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding	IMP
molecular_function	GO:0003677	DNA binding	IEA
molecular_function	GO:0003700	DNA-binding transcription factor activity	TAS

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000137	abnormal vertebrae morphology	"malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Prrx1^tm1Tex/Prrx1^tm1Tex,Prrx2^tm1Hubr/Prrx2^tm1Hubr Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: Not Specified Allelic Composition: Pax1^un/Pax1^un Genetic Background: Not Specified Allelic Composition: Pax1^tm1Neu/Pax1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0000139	absent transverse processes	"loss of bony protrusion of either side of the arch of a thoracic vertebrae" [J:62022, J:62023]	Show Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: Not Specified
MP:0000141	abnormal vertebral body morphology	"malformed main portion of the vertebra anterior to the vertebral canal" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]	Show Allelic Composition: Wnt3a^tm1Amc/Wnt3a^tm1Amc Genetic Background: involves: 129S1/Sv Allelic Composition: Pax1^tm2Neu/Pax1^tm2Neu Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax1^Un-s/Pax1^Un-s Genetic Background: B6.CC57BR-Pax1^Un-s Allelic Composition: kkt/kkt⁺,Pax1^un/Pax1⁺ Genetic Background: involves: C57BL/6 * CBA
MP:0000149	abnormal scapula morphology	"malformation of either or both of the large, flat bones of the back part of the shoulder" [J:13049]	Show Allelic Composition: Ptgs2^tm1Unc/Ptgs2^tm1Unc Genetic Background: D1.129P2(B6J)-Ptgs2^tm1Unc Allelic Composition: Pax1^un/Pax1^un Genetic Background: Not Specified Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0000150	abnormal rib morphology	"malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311]	Show Allelic Composition: Il4^tm1Rao/Il4^tm1Rao Genetic Background: involves: 129S6/SvEvTac * C57BL/6
MP:0000154	rib fusion	"appearance of one or more ribs as a single structure" [J:62022, J:62023]	Show Allelic Composition: Wnt3a^tm1Amc/Wnt3a^tm1Amc Genetic Background: involves: 129S1/Sv
MP:0000157	abnormal sternum morphology	"malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212]	Show Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax1^tm1Neu/Pax1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0000160	kyphosis	"forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Pax1^un/Pax1^un Genetic Background: Not Specified
MP:0000161	scoliosis	"lateral and rotational curvature of the spine" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53770, J:66943]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: Not Specified Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0000352	decreased cell proliferation	"less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Pax1^tm1.1Tlu/Pax1^tm1.1Tlu Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
MP:0000454	abnormal jaw morphology	"malformation of the bony framework of the mouth where the teeth are held" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Efnb1^tm1.1Sor/Efnb1⁺,Efnb2^tm2Sor/Efnb2⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J
MP:0000516	abnormal urinary system morphology	"structural or developmental anomaly of any of the organs involved in the production or excretion of urine " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Tcf3^tm1Cmu/Tcf3^tm1Cmu Genetic Background: either: 129P2/OlaHsd-Tcf3^tm1Cmu or (involves: 129P2/OlaHsd * FVB/N)
MP:0000564	syndactyly	"any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Efnb1^tm1.1Sor/Efnb1⁺,Efnb2^tm2Sor/Efnb2⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J
MP:0000585	kinked tail	"a sharp bend or zig-zag in the tail" [J:61295]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^un/Pax1^un Genetic Background: Not Specified Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Lasp1^{Tg(Col1a1-lacZ)1Ngma}/Lasp1^{Tg(Col1a1-lacZ)1Ngma},Pax1^un-ex/Pax1^un-ex Genetic Background: involves: C57BL/6 Allelic Composition: Pax1^tm2.1Tlu/Pax1^tm2.1Tlu Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ Allelic Composition: Pax1^m1Btlr/Pax1^m1Btlr Genetic Background: C57BL/6J-Pax1^m1Btlr
MP:0000592	short tail	"reduced length of tail compared to control " [J:55583]	Show Allelic Composition: Pax1^un/Pax1^un Genetic Background: Not Specified Allelic Composition: Pax1^Un-s/Pax1^Un-s Genetic Background: B6.CC57BR-Pax1^Un-s Allelic Composition: Pax1^tm2.1Tlu/Pax1^tm2.1Tlu Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ Allelic Composition: Pax1^Un-s/Pax1⁺ Genetic Background: CC57BR/MvY
MP:0000715	decreased thymocyte number	"fewer than expected number of precursors to T cells; these cells are lymphoid cells found in the thymus " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^un-i/Pax1⁺ Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0000733	abnormal muscle development	"anomalous differentiation of muscle tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Wnt3a^tm1Amc/Wnt3a^tm1Amc Genetic Background: involves: 129S1/Sv
MP:0000737	abnormal myotome development	"malformation of or absence of the part of the somite that develops into the musculature" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:29279]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0000929	open neural tube	"incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571]	Show Allelic Composition: Pax1^un/Pax1⁺,Tcf3^tm1Cmu/Tcf3^tm1Cmu Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
MP:0000961	abnormal dorsal root ganglia morphology	"malformed group of nerve cell bodies of each segmental nerve projecting from the spinal cord " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:60159]	Show Allelic Composition: Wnt3a^tm1Amc/Wnt3a^tm1Amc Genetic Background: involves: 129S1/Sv
MP:0001258	decreased body length	"decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]	Show Allelic Composition: Wnt3a^tm1Amc/Wnt3a^tm1Amc Genetic Background: involves: 129S1/Sv
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Pax1^tm1.1Tlu/Pax1^tm1.1Tlu Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
MP:0001392	abnormal locomotor activity	"altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ptgs2^tm1Unc/Ptgs2^tm1Unc Genetic Background: D1.129P2(B6J)-Ptgs2^tm1Unc
MP:0001924	infertility	"inability to produce live offspring" [J:47225]	Show Allelic Composition: Tcf3^tm1Cmu/Tcf3^tm1Cmu Genetic Background: either: 129P2/OlaHsd-Tcf3^tm1Cmu or (involves: 129P2/OlaHsd * FVB/N)
MP:0002111	abnormal tail morphology	"abnormal development of the tail resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Efnb1^tm1.1Sor/Efnb1⁺,Efnb2^tm2Sor/Efnb2⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: Not Specified Allelic Composition: Pax1^un/Pax1^un Genetic Background: Not Specified Allelic Composition: Pax1^Un-s/Pax1⁺ Genetic Background: CC57BR/MvY
MP:0002114	abnormal axial skeleton morphology	"abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Cryaa^tm1Ady/Cryaa⁺ Genetic Background: involves: 129
MP:0002116	abnormal craniofacial bone morphology	"abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Efnb1^tm1.1Sor/Efnb1⁺,Efnb2^tm2Sor/Efnb2⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J
MP:0002145	abnormal T lymphocyte development	"atypical production of or inability to produce mature T cells, and/or accumulation of T cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Tcf3^tm1Cmu/Tcf3^tm1Cmu Genetic Background: either: 129P2/OlaHsd-Tcf3^tm1Cmu or (involves: 129P2/OlaHsd * FVB/N)
MP:0002151	abnormal neural tube morphology/development	"anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Wnt3a^tm1Amc/Wnt3a^tm1Amc Genetic Background: involves: 129S1/Sv
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Plcb3^tm1Dwu/Plcb3^tm1Dwu Genetic Background: Not Specified Allelic Composition: Pax1^tm1.1Tlu/Pax1^tm1.1Tlu Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
MP:0002759	abnormal caudal vertebrae morphology	"malformed bony segments of the tail, usually 27-30 present" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:82849]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^un/Pax1^un Genetic Background: Not Specified Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0002825	abnormal notochord	"malformation or absence of the axial fibrocellular cord in embryos around which develops the vertebral primordia" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0002938	white spotting	"the appearance of patches of white fur" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Gt(ROSA)26Sor^tm1(DTA)Lky/Gt(ROSA)26Sor^tm1(DTA)Lky,Tg(Cd4-cre)1Cwi/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
MP:0002940	variable body spotting	"the appearance of patches of white fur at random on the coat" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Gt(ROSA)26Sor^tm1(DTA)Lky/Gt(ROSA)26Sor^tm1(DTA)Lky,Tg(Cd4-cre)1Cwi/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
MP:0003047	abnormal thoracic vertebrae morphology	"malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: B6.Cg-Pax1^un-ex Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: Not Specified Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax1^Un-s/Pax1^Un-s Genetic Background: B6.CC57BR-Pax1^Un-s Allelic Composition: kkt/kkt⁺,Pax1^un/Pax1⁺ Genetic Background: involves: C57BL/6 * CBA
MP:0003048	abnormal cervical vertebrae morphology	"malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Efnb1^tm1.1Sor/Efnb1⁺,Efnb2^tm2Sor/Efnb2⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax1^un/Pax1^un Genetic Background: B6.Cg-Pax1^un Allelic Composition: Pax1^Un-s/Pax1^Un-s Genetic Background: B6.CC57BR-Pax1^Un-s
MP:0003049	abnormal lumbar vertebrae morphology	"malformation of any or all of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: B6.Cg-Pax1^un-ex Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: Not Specified Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax1^tm1Neu/Pax1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax1^un/Pax1^un Genetic Background: B6.Cg-Pax1^un Allelic Composition: Pax1^Un-s/Pax1^Un-s Genetic Background: B6.CC57BR-Pax1^Un-s Allelic Composition: Lasp1^{Tg(Col1a1-lacZ)1Ngma}/Lasp1^{Tg(Col1a1-lacZ)1Ngma},Pax1^un-ex/Pax1^un-ex Genetic Background: involves: C57BL/6 Allelic Composition: kkt/kkt⁺,Pax1^un/Pax1⁺ Genetic Background: involves: C57BL/6 * CBA
MP:0003051	curly tail	"a loop or corkscrew-like curl in the tail" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Pax1^un/Pax1⁺,Tcf3^tm1Cmu/Tcf3^tm1Cmu Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
MP:0003054	spina bifida	"common congenital midline defect of fusion of the vertebral arch" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]	Show Allelic Composition: Wnt3a^tm1Amc/Wnt3a^tm1Amc Genetic Background: involves: 129S1/Sv Allelic Composition: Pax1^un/Pax1⁺,Tcf3^tm1Cmu/Tcf3^tm1Cmu Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
MP:0003795	abnormal bone structure		Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0003944	abnormal T cell subpopulation ratio	"deviation from the standard ratios of T cell subpopulations (e.g. double positive to single positive ratio) compared to control samples" [mberry:Melissa Berry, Genetics Resources Curator]	Show Allelic Composition: Pax1^un/Pax1⁺,Tcf3^tm1Cmu/Tcf3^tm1Cmu Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
MP:0004083	polysyndactyly	"greater than 5 digits present on an autopod with interdigital webbing also present" [rbabiuk:Randall Babiuk, Mouse Genome Informatics Curator]	Show Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: B6.Cg-Pax1^un-ex
MP:0004173	abnormal intervertebral disk morphology	"malformation of the cartilagenous and gelatinous structure found between vertebrae" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^Un-s/Pax1^Un-s Genetic Background: B6.CC57BR-Pax1^Un-s
MP:0004206	abnormal dermomyotome development	"any structural anomaly of the portion of the embryonic somite that remains after migration of the sclerotomic tissue" [J:50279, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Wnt3a^tm1Amc/Wnt3a^tm1Amc Genetic Background: involves: 129S1/Sv
MP:0004345	abnormal acromion morphology	"any structural anomaly of the lateral end of the spine of the scapula which projects as a broad flattened process and articulates with the clavicle, and forms the point of the shoulder" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: kkt/kkt⁺,Pax1^un/Pax1⁺ Genetic Background: involves: C57BL/6 * CBA
MP:0004346	absent acromion	"missing the lateral end of the spine of the scapula which projects as a broad flattened process and articulates with the clavicle, and forms the point of the shoulder" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^un/Pax1^un Genetic Background: Not Specified Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0004347	abnormal scapular spine morphology	"any structural anomaly of the trianguar ridge on the dorsal aspect of the scapula which separates the supra- from the infraspinatous fossa and where the trapezius and deltoid muscles are attached " [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0004353	abnormal deltoid tuberosity morphology	"any structural anomaly of a rough elevation at the middle of the lateral side of the shaft of the humerus to which the deltoid muscle attaches" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0004604	abnormal vertebral pedicle morphology	"any structural anomaly of the two short, thick processes, which project backward, one on either side, from the upper part of the body to the laminae" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Wnt3a^tm1Amc/Wnt3a^tm1Amc Genetic Background: involves: 129S1/Sv Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: Not Specified
MP:0004605	abnormal vertebral lamina morphology	"any structural anomaly of two broad plates directed dorsomedially from the pedicles; these fuse at the dorsal midline, and complete the dorsal wall of the vertebral foramen " [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Wnt3a^tm1Amc/Wnt3a^tm1Amc Genetic Background: involves: 129S1/Sv
MP:0004607	abnormal cervical atlas morphology	"any structural anomaly of the first (topmost, C1) cervical vertebra which supports the globe of the head" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax1^tm1Neu/Pax1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0004608	abnormal cervical axis morphology	"any structural anomaly of the second cervical vertebra (C2) which forms the pivot upon which the first cervical (atlas, C1) vertebra rotates" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0004609	vertebral fusion	"the union of one or more vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Wnt3a^tm1Amc/Wnt3a^tm1Amc Genetic Background: involves: 129S1/Sv
MP:0004624	abnormal thoracic cage	"any structural anomaly of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Lasp1^{Tg(Col1a1-lacZ)1Ngma}/Lasp1^{Tg(Col1a1-lacZ)1Ngma},Pax1^un-ex/Pax1^un-ex Genetic Background: involves: C57BL/6
MP:0004625	abnormal rib attachment	"any anomaly in the in the normal joining of the ribs to the vertebral column or to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: B6.Cg-Pax1^un-ex Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax1^un/Pax1^un Genetic Background: B6.Cg-Pax1^un Allelic Composition: Pax1^Un-s/Pax1^Un-s Genetic Background: B6.CC57BR-Pax1^Un-s
MP:0004626	vertebral compression	"appearance of vertebrae that are flattened laterally along the whole length such that they appear pressed together and take up less rostrocaudal space " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: Not Specified Allelic Composition: Lasp1^{Tg(Col1a1-lacZ)1Ngma}/Lasp1^{Tg(Col1a1-lacZ)1Ngma},Pax1^un-ex/Pax1^un-ex Genetic Background: involves: C57BL/6
MP:0004652	small caudal vertebrae	"reduced size of the bony segments of the coccyx or tail; there are usually 27-30 present in rodents and only 3-5 fused vertebrae in human" [MESH:National Library of Medicine_Medical Subject Headings]	Show Allelic Composition: Pax1^un/Pax1^un Genetic Background: Not Specified
MP:0004658	abnormal ventral tubercle of atlas	"any structural anomaly of the conical ventral projection on the arch of the atlas" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax1^tm1Neu/Pax1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0004667	vertebral body hypoplasia	"underdevelopment or reduced size, usually due to a reduced number of cells, of the main cylindrical portion of the vertebra ventral to the vertebral canal" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0004668	absent vertebral body	"absence of the main cylindrical portion of the vertebra ventral to the vertebral canal" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Prrx1^tm1Tex/Prrx1^tm1Tex,Prrx2^tm1Hubr/Prrx2^tm1Hubr Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: Not Specified Allelic Composition: Pax1^Un-s/Pax1^Un-s Genetic Background: B6.CC57BR-Pax1^Un-s
MP:0004670	small vertebral body	"decreased size of the main cylindrical portion of the vertebra ventral to the vertebral canal" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Pax1^tm2Neu/Pax1^tm2Neu Genetic Background: involves: 129S1/Sv * C57BL/6
MP:0004683	absent intervertebral disk	"absence of the cartilaginous and gelatinous structure found between vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Prrx1^tm1Tex/Prrx1^tm1Tex,Prrx2^tm1Hubr/Prrx2^tm1Hubr Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB Allelic Composition: Foxc2^tm1Miu/Foxc2^tm1Miu,Pax1^tm2Neu/Pax1^tm2Neu Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: Not Specified Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Pax1^Un-s/Pax1^Un-s Genetic Background: B6.CC57BR-Pax1^Un-s
MP:0004687	split vertebrae	"any vertebrae or vertebral section that is cleft into two parts " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: Not Specified
MP:0004703	abnormal vertebral column	"any structural anomaly of the complete structure forming the rostral-caudal axis of the skeleton formed from the alternating segments of vertebra and intervertebral discs which support the spinal cord" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: B6.Cg-Pax1^un-ex Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: Not Specified Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0004704	short vertebral column	"decreased rostral-caudal length of the complete structure forming the rostral-caudal axis of the skeleton formed from the alternating segments of vertebra and intervertebral discs which support the spinal cord" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Foxc2^tm1Miu/Foxc2^tm1Miu,Pax1^tm2Neu/Pax1^tm2Neu Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6
MP:0004787	abnormal dorsal aorta morphology	"any structural anomaly of the paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation" [ISBN:0-914294-08-3 "Gray s Anatomy"]	Show Allelic Composition: Foxc2^tm1Miu/Foxc2^tm1Miu,Pax1^tm2Neu/Pax1^tm2Neu Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6
MP:0005089	decreased double-negative T cell count	"reduced numbers of the subset of T cells found in the thymus that express neither CD4 nor CD8 " [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0005090	increased double-negative T cells count	"greater than expected numbers of the subset of T cells found in the thymus that express neither CD4 nor CD8" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0005092	decreased double-positive T cell count	"less than the expected number of the subset of T cells found in the thymus that express both CD4 and CD8" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0005225	abnormal vertebrae development	"anomalous formation of the vertebrae from the sclerotome" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Wnt3a^tm1Amc/Wnt3a^tm1Amc Genetic Background: involves: 129S1/Sv Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^un/Pax1^un Genetic Background: Not Specified
MP:0005226	abnormal vertebral arch development	"anomalous formation of the posterior projection from the body of a vertebra that encloses the vertebral foramen " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0005229	abnormal intervertebral disk development	"anomalous fromation of the cartilagenous and gelatinous structure found between vertebrae" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Pax1^un/Pax1^un Genetic Background: Not Specified
MP:0005296	abnormal humerus morphology	"malformation of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0005297	spina bifida occulta	"common congenital midline defect of fusion of the vertebral arch without protrusion of the spinal cord or meninges" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Gt(ROSA)26Sor^tm1(DTA)Lky/Gt(ROSA)26Sor^tm1(DTA)Lky,Tg(Cd4-cre)1Cwi/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
MP:0005508	abnormal skeleton morphology	"malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pax1^tm2Neu/Pax1^tm2Neu Genetic Background: involves: 129S1/Sv * C57BL/6
MP:0006029	abnormal sclerotome	"malformation of the one or more of the masses of mesodermal tissue that is derived from the somites and is adjacent to the notochord that give rise to the ribs and vertebrae" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99]	Show Allelic Composition: Wnt3a^tm1Amc/Wnt3a^tm1Amc Genetic Background: involves: 129S1/Sv
MP:0006295	absent sclerotome	"absence of the group of mesenchymal cells that emerge from the ventromedial part of a somite and migrate toward the notochord to give rise to the ribs and vertebrae" [J:60303, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0008075	decreased CD4-positive T cell number	"reduced number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^un-i/Pax1⁺ Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0008079	decreased CD8-positive T cell number	"reduction in the number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^un-i/Pax1⁺ Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0008149	abnormal rib-vertebral column attachment	"any anomaly in the in the normal joining of the ribs to the vertebral column" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Prrx1^tm1Tex/Prrx1^tm1Tex,Prrx2^tm1Hubr/Prrx2^tm1Hubr Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB Allelic Composition: Foxc2^tm1Miu/Foxc2^tm1Miu,Pax1^tm2Neu/Pax1^tm2Neu Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 Allelic Composition: Pax1^un-ex/Pax1^un-ex Genetic Background: Not Specified
MP:0009037	abnormal subarachnoid space development	"anomaly in the formation of the space between the arachnoid and dura mater that is traversed by fibrous trabeculae and contains cerebrospinal fluid" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Foxc2^tm1Miu/Foxc2^tm1Miu,Pax1^tm2Neu/Pax1^tm2Neu Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6
MP:0009929	meningomyelocele	"hernial protrusion of the spinal cord and its meninges through an opening or defect in the vertebral column" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Foxc2^tm1Miu/Foxc2^tm1Miu,Pax1^tm2Neu/Pax1^tm2Neu Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6
MP:0010082	sternebra fusion	"appearance of one or more sternebrae as a single structure" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0010701	fusion of atlas and odontoid process	"the large protuberance that projects upward from the cervical axis (C2), around which the cervical atlas normally rotates, is instead fused to elements of the atlas; the odontoid process may or may not remain attached to the axis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Foxc2^tm1Miu/Foxc2^tm1Miu,Pax1^tm2Neu/Pax1^tm2Neu Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Pax1^tm1Neu/Pax1^tm1Neu Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0011086	partial postnatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Pax1^un/Pax1⁺,Tcf3^tm1Cmu/Tcf3^tm1Cmu Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
MP:0011090	partial perinatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]	Show Allelic Composition: Foxc2^tm1Miu/Foxc2^tm1Miu,Pax1^tm2Neu/Pax1^tm2Neu Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6
MP:0011400	complete lethality	"all individuals of a given genotype in a population die before the end of the normal lifespan but time(s) of death are unspecified" [MGI:llw2]	Show Allelic Composition: Pax1^Un-s/Pax1⁺ Genetic Background: CC57BR/MvY
MP:0013176	abnormal tail position or orientation	" tail is displaced from the normal location and/or does not orient in a typical pattern" [MGI:anna]	Show Allelic Composition: Pax1^un-i/Pax1^un-i Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0013179	wavy tail	"undulations or a sinusoidal shape of the tail" [MGI:anna]	Show Allelic Composition: Pax1^Un-s/Pax1⁺ Genetic Background: CC57BR/MvY

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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