ENSGALG00000012135


Gallus gallus

Features
Gene ID: ENSGALG00000012135
  
Biological name :ATF4
  
Synonyms : activating transcription factor 4 / ATF4
  
Possible biological names infered from orthology : Cyclic AMP-dependent transcription factor ATF-4 / P18848 / Q06507
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 50633582
Gene end: 50636513
  
Corresponding Affymetrix probe sets: Gga.19718.1.A1_s_at (Chicken Array)   Gga.19718.1.S1_s_at (Chicken Array)   Gga.3457.1.S1_at (Chicken Array)   Gga.3457.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000064669
Ensembl peptide - ENSGALP00000037099
NCBI entrez gene - 395693     See in Manteia.
RefSeq - NM_204880
RefSeq Peptide - NP_990211
swissprot - Q9W610
swissprot - A0A1L1S0M5
Ensembl - ENSGALG00000012135
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atf4aENSDARG00000111939Danio rerio
 atf4bENSDARG00000038141Danio rerio
 ATF4ENSG00000128272Homo sapiens
 Atf4ENSMUSG00000042406Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004827  Basic-leucine zipper domain
 IPR029811  cAMP-dependent transcription factor ATF-4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006094 gluconeogenesis IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0032922 circadian regulation of gene expression IEA
 biological_processGO:0034198 cellular response to amino acid starvation IEA
 biological_processGO:0034976 response to endoplasmic reticulum stress IEA
 biological_processGO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress IEA
 biological_processGO:0036499 PERK-mediated unfolded protein response IEA
 biological_processGO:0042149 cellular response to glucose starvation IEA
 biological_processGO:0042789 mRNA transcription by RNA polymerase II IEA
 biological_processGO:0043525 positive regulation of neuron apoptotic process IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045943 positive regulation of transcription by RNA polymerase I IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IEA
 biological_processGO:1903204 negative regulation of oxidative stress-induced neuron death IEA
 biological_processGO:1903351 cellular response to dopamine IEA
 biological_processGO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0034399 nuclear periphery IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:1990037 Lewy body core IEA
 cellular_componentGO:1990589 ATF4-CREB1 transcription factor complex IEA
 cellular_componentGO:1990590 ATF1-ATF4 transcription factor complex IEA
 cellular_componentGO:1990617 CHOP-ATF4 complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0043522 leucine zipper domain binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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