ENSGALG00000013626


Gallus gallus

Features
Gene ID: ENSGALG00000013626
  
Biological name :GMNN
  
Synonyms : geminin / GMNN
  
Possible biological names infered from orthology : geminin, DNA replication inhibitor / O75496 / O88513
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 90523233
Gene end: 90528650
  
Corresponding Affymetrix probe sets: GgaAffx.12241.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000041542
Ensembl peptide - ENSGALP00000058739
Ensembl peptide - ENSGALP00000055703
Ensembl peptide - ENSGALP00000022130
NCBI entrez gene - 421004     See in Manteia.
RefSeq - NM_001031010
RefSeq - XM_015282385
RefSeq - XM_015282386
RefSeq Peptide - NP_001026181
swissprot - A0A1L1RJ16
swissprot - A0A1D5PS24
swissprot - F1NW42
Ensembl - ENSGALG00000013626
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gmnnENSDARG00000035957Danio rerio
 GMNNENSG00000112312Homo sapiens
 GmnnENSMUSG00000006715Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR022786  Geminin/Multicilin
 IPR029697  Geminin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006275 regulation of DNA replication IEA
 biological_processGO:0008156 negative regulation of DNA replication IEA
 biological_processGO:0009887 animal organ morphogenesis IEA
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0035563 positive regulation of chromatin binding IEA
 biological_processGO:0045786 negative regulation of cell cycle IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0065003 protein-containing complex assembly IEA
 biological_processGO:0071163 DNA replication preinitiation complex assembly IEA
 biological_processGO:1902596 negative regulation of DNA replication origin binding IMP
 biological_processGO:2000104 negative regulation of DNA-dependent DNA replication IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0070491 repressing transcription factor binding IEA


Pathways (from Reactome)
Pathway description
CDT1 association with the CDC6:ORC:origin complex
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction / complex
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction / complex






 

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