ENSGALG00000013731


Gallus gallus

Features
Gene ID: ENSGALG00000013731
  
Biological name :SOCS6
  
Synonyms : SOCS6 / suppressor of cytokine signaling 6
  
Possible biological names infered from orthology : O14544 / Q9JLY0
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 93855854
Gene end: 93859057
  
Corresponding Affymetrix probe sets: Gga.1346.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000036145
NCBI entrez gene - 421020     See in Manteia.
RefSeq - NM_001127312
RefSeq - XM_015282390
RefSeq - XM_015282391
RefSeq Peptide - NP_001120784
swissprot - B2WUP2
Ensembl - ENSGALG00000013731
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 socs6aENSDARG00000058565Danio rerio
 SOCS6ENSG00000170677Homo sapiens
 Socs6ENSMUSG00000056153Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SOCS5 / suppressor of cytokine signaling 5 / O54928* / O75159*ENSGALG0000001001621
SOCS7* / O14512* / Q8VHQ2* / suppressor of cytokine signaling 7*ENSGALG0000004065819
SOCS4 / suppressor of cytokine signaling 4 / Q8WXH5* / Q91ZA6*ENSGALG0000001217918
CISH / cytokine-inducible SH2-containing protein / Q62225* / Q9NSE2*ENSGALG0000000226013
SOCS3 / suppressor of cytokine signaling 3 / O14543* / O35718*ENSGALG0000002778610
SOCS2 / suppressor of cytokine signaling 2 / O14508* / O35717*ENSGALG0000001129510
SOCS1 / suppressor of cytokine signaling 1 / O15524* / O35716*ENSGALG000000071589
SOCS1L / uncharacterized protein LOC417978 ENSGALG000000231938


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001496  SOCS box domain
 IPR028421  Suppressor of cytokine signalling 6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0010498 proteasomal protein catabolic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0050868 negative regulation of T cell activation IEA
 cellular_componentGO:0001772 immunological synapse IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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