ENSGALG00000014686


Gallus gallus

Features
Gene ID: ENSGALG00000014686
  
Biological name :FBN2
  
Synonyms : FBN2 / fibrillin 2
  
Possible biological names infered from orthology : Fibrillin-2 Fibrillin-2 C-terminal peptide / P35556 / Q61555
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 56764456
Gene end: 56924146
  
Corresponding Affymetrix probe sets: Gga.200.1.S1_at (Chicken Array)   Gga.200.2.S1_a_at (Chicken Array)   GgaAffx.11274.1.S1_at (Chicken Array)   GgaAffx.24486.1.S1_at (Chicken Array)   GgaAffx.24486.1.S1_s_at (Chicken Array)   GgaAffx.9303.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000023620
Ensembl peptide - ENSGALP00000055460
Ensembl peptide - ENSGALP00000049101
NCBI entrez gene - 374203     See in Manteia.
RefSeq - XM_004949379
RefSeq - XM_424715
swissprot - E1C3A6
swissprot - A0A1D5PRD6
swissprot - A0A1D5P8Q2
Ensembl - ENSGALG00000014686
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbn2aENSDARG00000051896Danio rerio
 FBN2ENSG00000138829Homo sapiens
 Fbn2ENSMUSG00000024598Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000003762574
FBN1 / fibrillin 1 / P35555* / Q61554* / Fibrillin-1 Asprosin*ENSGALG0000000496068
LTBP2 / latent transforming growth factor beta binding protein 2 / Q14767*ENSGALG0000001025817
LTBP1 / latent-transforming growth factor beta-binding protein 1 precursor / Q14766* / Q8CG19* / latent transforming growth factor beta binding protein 1*ENSGALG0000001044815
FBLN1 / fibulin-1 precursor / P23142* / Q08879* / fibulin 1* / Mus musculus fibulin 1 (Fbln1), transcript variant 2, mRNA.*ENSGALG000000142338
ENSGALG000000377115
FBLN5 / fibulin 5 / Q9UBX5* / Q9WVH9*ENSGALG000000107475
ENSGALG000000051204
EFEMP1 / EGF containing fibulin extracellular matrix protein 1 / Q12805* / Q8BPB5* / EGF-containing fibulin-like extracellular matrix protein 1 *ENSGALG000000379014


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR017878  TB domain
 IPR018097  EGF-like calcium-binding, conserved site
 IPR026823  Complement Clr-like EGF domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030326 embryonic limb morphogenesis IEA
 biological_processGO:0030501 positive regulation of bone mineralization IEA
 biological_processGO:0035108 limb morphogenesis IEA
 biological_processGO:0035583 sequestering of TGFbeta in extracellular matrix IEA
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0045669 positive regulation of osteoblast differentiation IEA
 biological_processGO:0048048 embryonic eye morphogenesis IEA
 biological_processGO:0060346 bone trabecula formation IEA
 biological_processGO:0090287 regulation of cellular response to growth factor stimulus IBA
 cellular_componentGO:0001527 microfibril IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0031012 extracellular matrix IBA
 molecular_functionGO:0005201 extracellular matrix structural constituent IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix
Elastic fibre formation
Molecules associated with elastic fibres


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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