ENSGALG00000037901


Gallus gallus

Features
Gene ID: ENSGALG00000037901
  
Biological name :EFEMP1
  
Synonyms : EFEMP1 / EGF containing fibulin extracellular matrix protein 1
  
Possible biological names infered from orthology : EGF-containing fibulin-like extracellular matrix protein 1 / Q12805 / Q8BPB5
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 242964
Gene end: 294071
  
Corresponding Affymetrix probe sets: Gga.5255.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047135
NCBI entrez gene - 428543     See in Manteia.
RefSeq - XM_426097
swissprot - A0A1D5P380
Ensembl - ENSGALG00000037901
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU570800.1ENSDARG00000059121Danio rerio
 si:ch73-173h19.3ENSDARG00000104210Danio rerio
 EFEMP1ENSG00000115380Homo sapiens
 Efemp1ENSMUSG00000020467Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FBLN5 / fibulin 5 / Q9UBX5* / Q9WVH9*ENSGALG0000001074745
FBLN1 / fibulin-1 precursor / P23142* / Q08879* / fibulin 1* / Mus musculus fibulin 1 (Fbln1), transcript variant 2, mRNA.*ENSGALG0000001423333
ENSGALG0000003771128
FBN1 / fibrillin 1 / P35555* / Q61554* / Fibrillin-1 Asprosin*ENSGALG0000000496025
FBN2 / fibrillin 2 / P35556* / Q61555* / Fibrillin-2 Fibrillin-2 C-terminal peptide*ENSGALG0000001468625
ENSGALG0000003762524
LTBP2 / latent transforming growth factor beta binding protein 2 / Q14767*ENSGALG0000001025822
LTBP1 / latent-transforming growth factor beta-binding protein 1 precursor / Q14766* / Q8CG19* / latent transforming growth factor beta binding protein 1*ENSGALG0000001044821
ENSGALG000000051201


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR026823  Complement Clr-like EGF domain
 IPR032973  EGF-containing fibulin-like extracellular matrix protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0032331 negative regulation of chondrocyte differentiation IEA
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0048048 embryonic eye morphogenesis IEA
 biological_processGO:0048050 post-embryonic eye morphogenesis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005006 epidermal growth factor-activated receptor activity IEA
 molecular_functionGO:0005154 epidermal growth factor receptor binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Molecules associated with elastic fibres


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004040 MFAP3 / microfibril-associated glycoprotein 3 precursor / P55082* / microfibril associated protein 3*  / complex / reaction
 ENSGALG00000028295 MFAP1 / microfibril associated protein 1 / Mfap1b* / P55081* / C0HKD9* / Mfap1a* / C0HKD8* / Microfibrillar-associated protein 1A *  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr