ENSGALG00000010747


Gallus gallus

Features
Gene ID: ENSGALG00000010747
  
Biological name :FBLN5
  
Synonyms : FBLN5 / fibulin 5
  
Possible biological names infered from orthology : Q9UBX5 / Q9WVH9
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 44523932
Gene end: 44565644
  
Corresponding Affymetrix probe sets: Gga.10096.1.S1_at (Chicken Array)   Gga.13086.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017464
Ensembl peptide - ENSGALP00000060971
NCBI entrez gene - 423413     See in Manteia.
RefSeq - NM_001277474
RefSeq Peptide - NP_001264403
swissprot - E1C1G8
swissprot - A0A1L1RQ98
Ensembl - ENSGALG00000010747
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbln5ENSDARG00000039273Danio rerio
 FBLN5ENSG00000140092Homo sapiens
 Fbln5ENSMUSG00000021186Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EFEMP1 / EGF containing fibulin extracellular matrix protein 1 / Q12805* / Q8BPB5* / EGF-containing fibulin-like extracellular matrix protein 1 *ENSGALG0000003790145
FBLN1 / fibulin-1 precursor / P23142* / Q08879* / fibulin 1* / Mus musculus fibulin 1 (Fbln1), transcript variant 2, mRNA.*ENSGALG0000001423336
ENSGALG0000003771130
FBN1 / fibrillin 1 / P35555* / Q61554* / Fibrillin-1 Asprosin*ENSGALG0000000496028
ENSGALG0000003762527
FBN2 / fibrillin 2 / P35556* / Q61555* / Fibrillin-2 Fibrillin-2 C-terminal peptide*ENSGALG0000001468626
LTBP2 / latent transforming growth factor beta binding protein 2 / Q14767*ENSGALG0000001025823
LTBP1 / latent-transforming growth factor beta-binding protein 1 precursor / Q14766* / Q8CG19* / latent transforming growth factor beta binding protein 1*ENSGALG0000001044823
ENSGALG000000051202


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR026823  Complement Clr-like EGF domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0034394 protein localization to cell surface IEA
 biological_processGO:0046903 secretion IEA
 biological_processGO:0048251 elastic fiber assembly IEA
 biological_processGO:2000121 regulation of removal of superoxide radicals IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 cellular_componentGO:0071953 elastic fiber IEA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Elastic fibre formation
Molecules associated with elastic fibres


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004040 MFAP3 / microfibril-associated glycoprotein 3 precursor / P55082* / microfibril associated protein 3*  / complex / reaction
 ENSGALG00000028295 MFAP1 / microfibril associated protein 1 / Mfap1b* / P55081* / C0HKD9* / Mfap1a* / C0HKD8* / Microfibrillar-associated protein 1A *  / reaction / complex






 

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