ENSGALG00000014991


Gallus gallus

Features
Gene ID: ENSGALG00000014991
  
Biological name :HDAC2
  
Synonyms : HDAC2 / histone deacetylase 2
  
Possible biological names infered from orthology : Q92769
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 64980431
Gene end: 65002757
  
Corresponding Affymetrix probe sets: Gga.2951.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044336
Ensembl peptide - ENSGALP00000061892
Ensembl peptide - ENSGALP00000061752
Ensembl peptide - ENSGALP00000057637
Ensembl peptide - ENSGALP00000044581
Ensembl peptide - ENSGALP00000024133
NCBI entrez gene - 395635     See in Manteia.
RefSeq - NM_204831
RefSeq - XM_015284494
RefSeq Peptide - NP_990162
swissprot - A0A1D5NVG1
swissprot - A0A1L1RSV7
swissprot - F1NM39
swissprot - A0A1L1RSH1
swissprot - A0A1D5NW46
Ensembl - ENSGALG00000014991
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HDAC2ENSG00000196591Homo sapiens
 Hdac2ENSMUSG00000019777Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HDAC1 / P56517 / Histone deacetylase 1 / O09106* / Q13547* / Gm10093*ENSGALG0000000329777
HDAC3 / histone deacetylase 3 / O15379*ENSGALG0000000263450
HDAC8 / histone deacetylase 8 / Q8VH37* / Q9BY41*ENSGALG0000000482532
HDAC11 / histone deacetylase 11 / Q91WA3* / Q96DB2*ENSGALG0000000509217


Protein motifs (from Interpro)
Interpro ID Name
 IPR000286  Histone deacetylase family
 IPR003084  Histone deacetylase
 IPR023801  Histone deacetylase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006344 maintenance of chromatin silencing IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010870 positive regulation of receptor biosynthetic process IEA
 biological_processGO:0016575 histone deacetylation IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0045862 positive regulation of proteolysis IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0070932 histone H3 deacetylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016580 Sin3 complex IEA
 cellular_componentGO:0016581 NuRD complex IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0035098 ESC/E(Z) complex IEA
 molecular_functionGO:0001103 RNA polymerase II repressing transcription factor binding IEA
 molecular_functionGO:0004407 histone deacetylase activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) IEA
 molecular_functionGO:0033558 protein deacetylase activity IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051059 NF-kappaB binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of chromatin organization proteins
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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