ENSGALG00000015415


Gallus gallus

Features
Gene ID: ENSGALG00000015415
  
Biological name :HACE1
  
Synonyms : E1C656 / E3 ubiquitin-protein ligase HACE1 / HACE1
  
Possible biological names infered from orthology : HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 / Q3U0D9 / Q8IYU2
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 69217077
Gene end: 69261301
  
Corresponding Affymetrix probe sets: GgaAffx.9822.1.S1_at (Chicken Array)   GgaAffx.9822.2.S1_at (Chicken Array)   GgaAffx.9822.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000060303
Ensembl peptide - ENSGALP00000024819
NCBI entrez gene - 421788     See in Manteia.
RefSeq - XM_015284531
RefSeq - NM_001278155
RefSeq - XM_015284529
RefSeq - XM_015284530
RefSeq Peptide - NP_001265084
swissprot - E1C656
Ensembl - ENSGALG00000015415
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hace1ENSDARG00000062280Danio rerio
 HACE1ENSG00000085382Homo sapiens
 Hace1ENSMUSG00000038822Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NEDD4L* / Q96PU5* / neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase*ENSGALG0000003458424
HECW1 / HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 / Q76N89* / Q8K4P8* / E3 ubiquitin-protein ligase HECW1 *ENSGALG0000003719323
NEDD4L* / Q96PU5* / neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase*ENSGALG0000003135523
WWP1 / WW domain containing E3 ubiquitin protein ligase 1 / Q8BZZ3* / Q9H0M0*ENSGALG0000004179523
HECW2 / HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 / Q6I6G8* / Q9P2P5* / E3 ubiquitin-protein ligase HECW2 *ENSGALG0000000794423
WWP2 / NEDD4-like E3 ubiquitin-protein ligase WWP2 / O00308* / Q9DBH0* / WW domain containing E3 ubiquitin protein ligase 2*ENSGALG0000000069922
SMURF1 / SMAD specific E3 ubiquitin protein ligase 1 / Q9CUN6* / Q9HCE7* / E3 ubiquitin-protein ligase SMURF1 *ENSGALG0000000465522
NEDD4 / neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase / P46934* / P46935* / neural precursor cell expressed, developmentally down-regulated 4*ENSGALG0000000434722
ITCH / itchy E3 ubiquitin protein ligase / Q8C863* / Q96J02* / E3 ubiquitin-protein ligase Itchy *ENSGALG0000004047422
SMURF2 / SMAD specific E3 ubiquitin protein ligase 2 / A2A5Z6* / Q9HAU4* / E3 ubiquitin-protein ligase SMURF2 *ENSGALG0000000356621


Protein motifs (from Interpro)
Interpro ID Name
 IPR000569  HECT domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process ISS
 biological_processGO:0007030 Golgi organization ISS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016567 protein ubiquitination ISS
 biological_processGO:0030334 regulation of cell migration ISS
 biological_processGO:0061025 membrane fusion ISS
 biological_processGO:0070936 protein K48-linked ubiquitination ISS
 cellular_componentGO:0000139 Golgi membrane ISS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017137 Rab GTPase binding ISS
 molecular_functionGO:0048365 Rac GTPase binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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