ENSGALG00000034584


Gallus gallus

Features
Gene ID: ENSGALG00000034584
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : NEDD4L / neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase / Q96PU5
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 613361
Gene end: 742150
  
Corresponding Affymetrix probe sets: Gga.2944.1.S1_s_at (Chicken Array)   Gga.2944.2.S1_a_at (Chicken Array)   Gga.63.1.S1_s_at (Chicken Array)   GgaAffx.21499.1.S1_at (Chicken Array)   GgaAffx.25682.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045309
Ensembl peptide - ENSGALP00000063853
Ensembl peptide - ENSGALP00000058428
Ensembl peptide - ENSGALP00000055519
NCBI entrez gene - 374119     See in Manteia.
RefSeq - XM_424462
RefSeq - XM_015277389
RefSeq - XM_015277390
RefSeq - XM_015277391
RefSeq - XM_015277392
RefSeq - XM_004948994
RefSeq - XM_004948995
RefSeq - XM_004948996
RefSeq - XM_004948997
RefSeq - XM_004948998
RefSeq - XM_004949000
swissprot - A0A1L1RYC9
swissprot - A0A1D5PZL4
swissprot - A0A1D5PRJ2
swissprot - A0A1D5NY54
Ensembl - ENSGALG00000034584
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nedd4lENSDARG00000060006Danio rerio
 NEDD4LENSG00000049759Homo sapiens
 Nedd4lENSMUSG00000024589Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NEDD4L* / Q96PU5* / neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase*ENSGALG0000003135592
NEDD4 / neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase / P46934* / P46935* / neural precursor cell expressed, developmentally down-regulated 4*ENSGALG0000000434759
ITCH / itchy E3 ubiquitin protein ligase / Q8C863* / Q96J02* / E3 ubiquitin-protein ligase Itchy *ENSGALG0000004047434
WWP1 / WW domain containing E3 ubiquitin protein ligase 1 / Q8BZZ3* / Q9H0M0*ENSGALG0000004179534
WWP2 / NEDD4-like E3 ubiquitin-protein ligase WWP2 / O00308* / Q9DBH0* / WW domain containing E3 ubiquitin protein ligase 2*ENSGALG0000000069933
HECW2 / HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 / Q6I6G8* / Q9P2P5* / E3 ubiquitin-protein ligase HECW2 *ENSGALG0000000794433
HECW1 / HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 / Q76N89* / Q8K4P8* / E3 ubiquitin-protein ligase HECW1 *ENSGALG0000003719332
SMURF1 / SMAD specific E3 ubiquitin protein ligase 1 / Q9CUN6* / Q9HCE7* / E3 ubiquitin-protein ligase SMURF1 *ENSGALG0000000465530
SMURF2 / SMAD specific E3 ubiquitin protein ligase 2 / A2A5Z6* / Q9HAU4* / E3 ubiquitin-protein ligase SMURF2 *ENSGALG0000000356630
HACE1 / E1C656 / E3 ubiquitin-protein ligase HACE1 / Q3U0D9* / Q8IYU2* / HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1*ENSGALG0000001541523


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000569  HECT domain
 IPR001202  WW domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Stimuli-sensing channels
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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