ENSGALG00000037193


Gallus gallus

Features
Gene ID: ENSGALG00000037193
  
Biological name :HECW1
  
Synonyms : HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 / HECW1
  
Possible biological names infered from orthology : E3 ubiquitin-protein ligase HECW1 / Q76N89 / Q8K4P8
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 51429079
Gene end: 51660281
  
Corresponding Affymetrix probe sets: GgaAffx.20797.1.S1_at (Chicken Array)   GgaAffx.7819.1.S1_s_at (Chicken Array)   GgaAffx.7819.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046221
Ensembl peptide - ENSGALP00000050897
Ensembl peptide - ENSGALP00000047326
NCBI entrez gene - 420774     See in Manteia.
RefSeq - XM_418870
RefSeq - XM_015281619
RefSeq - XM_015281620
RefSeq - XM_015281621
RefSeq - XM_015281615
RefSeq - XM_015281616
RefSeq - XM_015281617
swissprot - A0A1D5PDQ2
swissprot - A0A1D5P3S1
swissprot - A0A1D5P0P3
Ensembl - ENSGALG00000037193
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hecw1bENSDARG00000004291Danio rerio
 si:ch211-188f17.1ENSDARG00000100958Danio rerio
 HECW1ENSG00000002746Homo sapiens
 Hecw1ENSMUSG00000021301Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HECW2 / HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 / Q6I6G8* / Q9P2P5* / E3 ubiquitin-protein ligase HECW2 *ENSGALG0000000794455
NEDD4L* / Q96PU5* / neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase*ENSGALG0000003458420
ITCH / itchy E3 ubiquitin protein ligase / Q8C863* / Q96J02* / E3 ubiquitin-protein ligase Itchy *ENSGALG0000004047419
NEDD4L* / Q96PU5* / neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase*ENSGALG0000003135519
NEDD4 / neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase / P46934* / P46935* / neural precursor cell expressed, developmentally down-regulated 4*ENSGALG0000000434718
WWP1 / WW domain containing E3 ubiquitin protein ligase 1 / Q8BZZ3* / Q9H0M0*ENSGALG0000004179518
WWP2 / NEDD4-like E3 ubiquitin-protein ligase WWP2 / O00308* / Q9DBH0* / WW domain containing E3 ubiquitin protein ligase 2*ENSGALG0000000069918
SMURF2 / SMAD specific E3 ubiquitin protein ligase 2 / A2A5Z6* / Q9HAU4* / E3 ubiquitin-protein ligase SMURF2 *ENSGALG0000000356616
SMURF1 / SMAD specific E3 ubiquitin protein ligase 1 / Q9CUN6* / Q9HCE7* / E3 ubiquitin-protein ligase SMURF1 *ENSGALG0000000465516
HACE1 / E1C656 / E3 ubiquitin-protein ligase HACE1 / Q3U0D9* / Q8IYU2* / HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1*ENSGALG0000001541514


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000569  HECT domain
 IPR001202  WW domain
 IPR032348  E3 ubiquitin-protein ligase HECW1/2, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Degradation of DVL


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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